Results 221 to 230 of about 143,975 (276)

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl, Mies Bethäuser, Daniela Nürnberger, Stefan Oswald, Andreas Moritz, Melanie Hamann, Joachim Geyer   +6 more
wiley   +1 more source

A β-galactosidase activated near-infrared fluorescent probe for tracking cellular senescence in vitro and in vivo. [PDF]

Smart Mol
Su T, Shen R, Tu D, Han X, Luo X, Yu F.
europepmc   +1 more source

Rhizobial motility preference in root colonization of Medicago truncatula

New Phytologist, EarlyView.
Summary Tunnel‐like infection thread (IT) structures support root colonization by symbiotic nitrogen‐fixing rhizobia bacteria in most legume species. These tip‐grown structures are key to directing rhizobia from root hairs to developing nodules, where they are hosted to fix nitrogen.
Anaïs Delers, Anne Bennion, Ambre Guillory, Lisa Frances, Elizaveta Krol, Fanny Bonnafous, Laurena Medioni, Javier Serrania, Rémi Peyraud, Joëlle Fournier, Fernanda de Carvalho‐Niebel, Anke Becker   +11 more
wiley   +1 more source

Corrigendum: Infection of a β-galactosidase-deficient mouse strain with Theiler's murine encephalomyelitis virus reveals limited immunological dysregulations in this lysosomal storage disease. [PDF]

Front Immunol
Wannemacher R, Stegmann F, Eikelberg D, Bühler M, Li D, Kohale SK, Asawapattanakul T, Ebbecke T, Raulf MK, Baumgärtner W, Lepenies B, Gerhauser I.   +11 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

Safety evaluation of the food enzyme β-galactosidase from the non-genetically modified <i>Kluyveromyces lactis</i> strain LAC-01. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Sramkova M, Van Loveren H, Vernis L, Lunardi S, Andryszkiewicz M, Marini E, Liu Y.   +17 more
europepmc   +1 more source

The Jasmonate‐Responsive SmMPK3–SmWRKY33 Module Positively Regulates Tanshinone Biosynthesis in Salvia miltiorrhiza

Plant Biotechnology Journal, EarlyView.
ABSTRACT Tanshinones, the major bioactive diterpenes in Salvia miltiorrhiza Bunge, are widely used to treat cardiovascular and cerebrovascular diseases. While jasmonates (JAs) are known to modulate tanshinones accumulation, the molecular link between JA signalling and tanshinone biosynthesis remains unclear.
Renjun Qu, Shiwei Wang, Xinxin Wang, Jiaming Peng, Juan Guo, Guanghong Cui, Tong Chen, Meilan Chen, Shuangshuang Zhao, Ye Shen   +9 more
wiley   +1 more source

Enhancing β-Galactosidase Performance for Galactooligosaccharides Preparation via Strategic Glucose Re-Tunneling. [PDF]

Int J Mol Sci
Zhao J, Niu D, Liu J, Jin Z, Mchunu NP, Singh S, Wang Z.   +6 more
europepmc   +1 more source

The Rhus chinensis Genome Provides Insights Into Tannin, Flavonoid Biosynthesis, and Glandular Trichome Development

Plant Biotechnology Journal, EarlyView.
ABSTRACT The “salt tree”, Rhus chinensis, holds significant economic and medicinal value due to its ability to produce Galla chinensis (Chinese gall/gallnut), a plant‐derived medicinal material used in both traditional Chinese and modern medicine that is rich in tannins and flavonoids. It is also renowned for its remarkable stress tolerance.
Zhaogeng Lu, Helin Zou, Jiawen Cui, Tongfei Wang, Lingyu Ma, Shixiong Ren, Yiwei Cao, Xi Zhang, Zixi Chen, Hongyan Bao, Ling Zhu, Yaning Cui, Ruili Li, Xiuyan Yang, Qikun Zhang, Zhili Wang, Wangxiang Zhang, Li Wang, Jinxing Lin, Biao Jin   +19 more
wiley   +1 more source

Lysis of Escherichia coli by colicin Ib contributes to bacterial cross-feeding by releasing active β-galactosidase. [PDF]

ISME J
Lerminiaux NA, Kaufman JM, Schnell LJ, Workman SD, Suchan DM, Kröger C, Ingalls BP, Cameron ADS.   +7 more
europepmc   +1 more source