Results 61 to 70 of about 2,747,637 (331)

Activated microglia release β-galactosidase that promotes inflammatory neurodegeneration. [PDF]

, 2023
Beta (β)-galactosidase is a lysosomal enzyme that removes terminal galactose residues from glycolipids and glycoproteins. It is upregulated in, and used as a marker for, senescent cells.

core   +2 more sources

Senescence Associated β-galactosidase Staining

Bio-Protocol, 2012
Detection of senescent cells using a cytochemical assay was first described in 1995 (Dimri et al., 1995). The identification of senescent cells is based on an increased level of lysosomal β-galactosidase activity (Kurz et al., 2000).
Michael Eccles, Caiyun Li
doaj   +1 more source

EXTRACTION AND CHARACTERIZATION OF Î’-GALACTOSIDASE ENZYME FROM ZIZIPHUS SPINA-CHRISTI FOR FOOD APPLICATIONS

International Journal of Advanced Research
Galactosidaseis an industrially important enzymewitha number of applications in dairy, fermentation, and food industries. The study was carried out to extract and characterize the galactosidase enzymefromZiziphusspina-christi,a therapeutic herb. The enzyme was studied for pH, temperature sensitivity, and heavy metal effects on enzyme activity.
Omar Almuharib, Anmar Nazar Hasan
openaire   +1 more source

Isolation of Carbohydrate Hydrolyzing Enzymes from Red Kidney Beans [PDF]

Journal of Agricultural Chemistry and Biotechnology
Humans and other monogastric animals lack certain glycosidase enzymes that are widely present in plant seeds and animal tissues. This   study aimed to extract glycosidase enzymes from red kidney bean seeds.
Nancy Taha
doaj   +1 more source

Invited review: Properties of β-galactosidases derived from Lactobacillaceae species and their capacity for galacto-oligosaccharide production

Journal of Dairy Science, 2023
: β-galactosidase (enzymatic class 3.2.1.23) is one of the dairy industry's most important and widely used enzymes. The enzyme is part of a large family known to catalyze hydrolysis and transglycosylation reactions.
Silvette Ruiz-Ramírez, Rafael Jiménez-Flores   +1 more
doaj   +1 more source

Atomic resolution cryo-EM structure of β-galactosidase

Structure, 2018
SUMMARY The advent of direct electron detectors has enabled the routine use of single particle cryo-EM approaches to determine structures of a variety of protein complexes at near-atomic resolution.
A. Bartesaghi, Cecilia Aguerrebere, V. Falconieri, S. Banerjee, L. Earl, Xing Zhu, N. Grigorieff, J. Milne, G. Sapiro, Xiong-Wu Wu, S. Subramaniam   +10 more
semanticscholar   +1 more source

β-Galactosidase

, 2017
β-galactosidase is used as a reporter for the quantitative analysis of gene expression. It is also used as a histochemical marker. This introduction briefly reviews the enzymatic reactions catalyzed by β-galactosidase and methods for assaying β ...
Pradeep D. Uchil, Priti Kumar, Arvindhan Nagarajan   +2 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Multiplexed detection and differentiation of bacterial enzymes and bacteria by color-encoded sensor hydrogels

Bioactive Materials, 2021
We report on the fabrication and characterization of color-encoded chitosan hydrogels for the rapid, sensitive and specific detection of bacterial enzymes as well as the selective detection of a set of tested bacteria through characteristic enzyme ...
Zhiyuan Jia, Mareike Müller, Tony Le Gall, Martijn Riool, Max Müller, Sebastian A.J. Zaat, Tristan Montier, Holger Schönherr   +7 more
doaj   +1 more source

MOESM1 of Combined 13C-assisted metabolomics and metabolic flux analysis reveals the impacts of glutamate on the central metabolism of high β-galactosidase-producing Pichia pastoris

, 2016
Additional file 1. Stoichiometric and carbon atom transition model for P. pastoris.
Liu, Ping, Huang, Mingzhi, Guo, Menglei, Qian, Jiangchao, Lin, Weilu, Chu, Ju, Zhuang, Yingping, Zhang, Siliang   +7 more
openaire   +1 more source