Hypericin enhances β-lactam antibiotics activity by inhibiting sarA expression in methicillin-resistant Staphylococcus aureus [PDF]
Acta Pharmaceutica Sinica B, 2019 Bacteremia is a life-threating syndrome often caused by methicillin-resistant Staphylococcus aureus (MRSA). Thus, there is an urgent need to develop novel approaches to successfully treat this infection.
Genzhu Wang +8 more
doaj +4 more sources
Antibiotics, 2023 Methicillin-resistant Staphylococcus aureus (MRSA), a global health concern, has prompted research into antibiotic adjuvants as a potential solution. Although our group previously reported the enhancing effects of gallic acid (GA) and methyl gallate (MG)
Pimsumon Jiamboonsri +2 more
doaj +2 more sources
Effect of β-Lactamase inhibitors on in vitro activity of β-Lactam antibiotics against Burkholderia cepacia complex species [PDF]
Antimicrobial Resistance and Infection Control, 2016 Background Bacteria belonging to the Burkholderia cepacia complex (Bcc) are an important cause of chronic respiratory tract infections in cystic fibrosis patients.
Annelien Everaert, Tom Coenye
doaj +4 more sources
Structural Insights for β-Lactam Antibiotics. [PDF]
Biomol Ther (Seoul), 2023 Antibiotic resistance has emerged as a global threat to modern healthcare systems and has nullified many commonly used antibiotics. β-Lactam antibiotics are among the most successful and occupy approximately two-thirds of the prescription antibiotic ...
Kim D +11 more
europepmc +2 more sources
Combatting Pseudomonas aeruginosa with β-Lactam Antibiotics: A Revived Weapon? [PDF]
AntibioticsPseudomonas aeruginosa is a significant threat to public health as an aggressive, opportunistic pathogen. The use of β-lactam antibiotics such as penicillins, cephalosporins, monobactams, and carbapenems remains a front-line treatment against P ...
Dylan W. Zhao, Christopher T. Lohans
doaj +2 more sources
The state and consideration for skin test of β-lactam antibiotics in pediatrics [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 β-lactam antibiotics are the most frequently used drugs and the most common drugs that cause allergic reactions in pediatrics. The occurrence of some allergic reactions can be predicted by skin testing, especially severe adverse reactions such as ...
Chunhui Gao +3 more
doaj +2 more sources
Conjugation of Polycationic Peptides Extends the Efficacy Spectrum of β‐Lactam Antibiotics [PDF]
Advanced ScienceAntibiotic‐resistant enterococci represent a significant global health challenge. Unfortunately, most β‐lactam antibiotics are not applicable for enterococcal infections due to intrinsic resistance.
Julia Werner +20 more
doaj +2 more sources
Pharmacokinetics of β-Lactam Antibiotics: Clues from the Past To Help Discover Long-Acting Oral Drugs in the Future [PDF]
ACS Infectious Diseases, 2018 β-Lactams represent perhaps the most important class of antibiotics yet discovered. However, despite many years of active research, none of the currently approved drugs in this class combine oral activity with long duration of action. Recent developments
Paul W Smith +6 more
semanticscholar +5 more sources
Effect of β-lactam antibiotics on the gut microbiota of term neonates [PDF]
Annals of Clinical Microbiology and Antimicrobialsβ-Lactam antibiotics are a class of antibiotics commonly used to treat bacterial infections. However, the effects of β-lactam antibiotics on term neonatal intestinal flora have not been fully elucidated. Hospitalized full-term newborns receiving β-lactam
Hongdan Gu +9 more
doaj +2 more sources
Novel β-lactam antibiotics versus other antibiotics for treatment of complicated urinary tract infections: a systematic review and meta-analysis [PDF]
Frontiers in PharmacologyBackgroundNovel β-lactam antibiotics as well as other kinds of antibiotics have been used to treat complicated urinary tract infections (cUTIs); however, their efficacy and safety remain controversial.ObjectiveWe conducted a systematic review with meta ...
Xiang hua Quan +5 more
doaj +2 more sources