Results 121 to 130 of about 74,405 (237)

Prevalence of Streptococcus mitis in the bacterial plaques associated with gingivitis and its sensitivity to β-lactam antibiotics

open access: yesمجله دانشکده دندانپزشکی اصفهان, 2010
Introduction: Bacterial plaque is the most common etiology of oral conditions such as dental caries, gingivitis and periodontal disease. One of the most common periodontal diseases is gingivitis.
M Azadeh   +3 more
doaj  

Reusing health records from farm animal practices at scale: A potential complementary method of surveillance

open access: yesVeterinary Record, EarlyView.
Abstract Background Disease in primary care frequently represents a surveillance blind spot, particularly for diseases affecting farm animals. Methods Electronic health records (EHRs) were collected from four farm animal veterinary practices in Wales (February 2024‒January 2025) as part of a pilot study.
Beverley Hopkins   +8 more
wiley   +1 more source

In vitro and in vivo evaluation of cephalosporins for the treatment of Lyme disease. [PDF]

open access: yes, 2018
BackgroundLyme disease accounts for >90% of all vector-borne disease cases in the United States and affect ~300,000 persons annually in North America.
Ambati, Aditya   +9 more
core  

Asp-120 Locates Zn2 for Optimal Metallo-β-lactamase Activity [PDF]

open access: yes, 2007
Metallo-β-lactamases are zinc-dependent hydrolases that inactivate β-lactam antibiotics, rendering bacteria resistant to them. Asp-120 is fully conserved in all metallo-β-lactamases and is central to catalysis.
Bennett, Brian   +5 more
core   +1 more source

Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy

open access: yesAllergy, EarlyView.
DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane   +12 more
wiley   +1 more source

Successful Application of the Mast Cell Activation Test in Immediate Hypersensitivity to Amoxicillin

open access: yesAllergy, EarlyView.
This study included 28 amoxicillin‐allergic patients and 11 healthy exposed controls. Mast cells were differentiated from CD34+ progenitors over 8 weeks using cytokine cocktails. The mast cell activation test involved sensitization with patient or control sera and stimulation with free amoxicillin or G4/G5‐AXO dendrimers with successfully activated ...
Jose A. Céspedes   +11 more
wiley   +1 more source

Trapping and Characterization of a Reaction Intermediate in Carbapenem Hydrolysis by \u3cem\u3eB. cereus\u3c/em\u3e Metallo-β-lactamase [PDF]

open access: yes, 2008
Metallo-β-lactamases hydrolyze most β-lactam antibiotics. The lack of a successful inhibitor for them is related to the previous failure to characterize a reaction intermediate with a clinically useful substrate.
Tioni, Mariana F.   +9 more
core   +1 more source

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey   +10 more
wiley   +1 more source

New ionic liquids and salts derived from β-Lactam antibiotics [PDF]

open access: yes, 2010
In recent years ionic liquids (ILs) have been increasing the popularity and the number of applications. Ionic liquids were used mainly as solvent in organic synthesis, but in recent years they are also used in analytical chemistry, separation chemistry ...
Branco, Luís   +6 more
core  

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