Results 111 to 120 of about 86,850 (260)

In silico identification of auxiliary factors genes required for β-lactam resistance

, 2023
Staphylococcus aureus is a type of bacteria commonly found on the skin and in the nasal passages of healthy individuals. However, it can also cause a range of infections in clinical settings. One of the most concerning aspects of S. aureus is its ability
Astudillo Skliarova, Igor Eduardo
core  

Duplex Recombinase Polymerase Amplification‐Lateral Flow Assay for Rapid Visual Detection of Critical Antibiotic Resistance Genes in Escherichia coli and Klebsiella pneumoniae From Positive Blood Cultures

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a pair of duplex RPA‐LFA assays for the simultaneous detection of critical resistance genes, blaCTX‐M/mcr‐1 and blaoxa‐48‐like/blaNDM, from hemoculture samples. Under optimized conditions, duplex RPA was performed at 37°C–38°C for 25 min, followed by LFA for 10–15 min.
Variya Nemidkanam, Pattamaporn Deechart, Nuntaree Chaichanawongsaroj   +2 more
wiley   +1 more source

Comprehensive analysis of β-lactam resistant non-typhoidal Salmonella Isolates: Phenotypic and genotypic insights from clinical samples in Japan

Journal of Global Antimicrobial Resistance
Objective: This study examines β-lactam-resistant non-typhoidal Salmonella isolates using phenotypic and genotypic analyses to elucidate resistance mechanisms and epidemiological characteristics. Methods: A total of 1663 clinical Salmonella spp. isolates
Hazim O. Khalifa, Shizuo Kayama, Hazem Ramadan, Liansheng Yu, Wataru Hayashi, Yo Sugawara, Sayaka Uchino Kondo, Farah Al Marzooq, Tetsuya Matsumoto, Motoyuki Sugai   +9 more
doaj   +1 more source

Evolutionary pathways towards β-lactam resistance in Haemophilus influenzae [PDF]

Antimicrobial resistance is among the greatest global health threats, causing over 1.2 million deaths annually, with projections of 10 million by 2050 if not effectively addressed.
Petersen, Sabine
core  

On‐site pilot‐scale advanced oxidation pretreatment of hospital wastewater: assessment of pharmaceuticals, pathogens, antibiotic resistance genes and acute ecotoxicity

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos, Iosifina Gounaki, Spyros Dokianakis, Georgios Gkotsis, Maria‐Christina Nika, Eleni Aleiferi, Athanasios S Stasinakis, Nikos Katsarakis, Nikolaos S Thomaidis, Thrassyvoulos Manios, Michalis S Fountoulakis, Danae Venieri   +11 more
wiley   +1 more source

Tunicamycin and β-Lactams with Five Membered Ring Structures Have Stronger Synergistic Effects Against Gram-Positive Bacteria

Zoonoses
The prevalence of antimicrobial resistance is increasing among gram-positive bacteria, particularly the resistance of methicillin-resistant Staphylococcus aureus (MRSA) to β-lactam antibiotics. Checkerboard minimum inhibitory concentration (MIC) assays,
Xueyangyang Bai, Jinjing Xue, Fei He, Xiaotong Yang, Houru Liu, Kuan Gu, Qianghua Lv, Yonglin Zhou   +7 more
doaj   +1 more source

Streamlining antibiotic use in community acquired pneumonia: A quality improvement initiative

Journal of Hospital Medicine, EarlyView.
Abstract Background Evidence suggests a 3‐day total duration and early transition to oral therapy is safe in hospitalized patients with community acquired pneumonia (CAP)—though such care is not standard in the United States. To implement these evidence‐based practices, a multidisciplinary group led by a hospitalist and antimicrobial stewardship ...
Claire E. Ciarkowski, Karen Howard, Hannah Imlay, Chaorong Wu, Christy L. Hopkins, Valerie M. Vaughn, Emily S. Spivak   +6 more
wiley   +1 more source

Role of β-Lactamase Inhibitors as Potentiators in Antimicrobial Chemotherapy Targeting Gram-Negative Bacteria

Antibiotics
Since the discovery of penicillin, β-lactam antibiotics have commonly been used to treat bacterial infections. Unfortunately, at the same time, pathogens can develop resistance to β-lactam antibiotics such as penicillins, cephalosporins, monobactams, and
Song Zhang, Xinyu Liao, Tian Ding, Juhee Ahn   +3 more
doaj   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

Journal of Raman Spectroscopy, EarlyView.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira, Adriano Moraes da Silva, Marcos Tadeu T. Pacheco, Landulfo Silveira Jr.   +3 more
wiley   +1 more source

Direct interaction between MreB and the RodA‐PBP2 complex organizes lateral cell wall synthesis in Escherichia coli

mLife, EarlyView.
Abstract The elongasome, or the Rod complex, orchestrates lateral peptidoglycan (PG) synthesis in many rod‐shaped bacteria. It consists of the actin‐like protein MreB, the PG synthase RodA‐PBP2 complex, as well as MreCD and RodZ. Although the loss or disruption of any elongasome component results in a loss of rod shape, previous studies found that a ...
Rui Zhan, Han Gong, Ying Li, Xiangdong Chen, Joe Lutkenhaus, Shishen Du   +5 more
wiley   +1 more source