Results 231 to 240 of about 762,836 (292)

Altered Pathogen Spectrum of Spontaneous Bacterial Peritonitis in Patients Treated With Proton Pump Inhibitors

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 11, Page 1487-1494, June 2026.
This multicenter, observational study reveals distinct alterations in the microbial spectrum of spontaneous bacterial peritonitis (SBP) associated with proton pump inhibitor use. These results are especially relevant for guiding empiric antibiotic therapy of SBP.
Philip Kitchen, Sarah L. Schütte, Tammo L. Tergast, Benjamin Maasoumy, Leonie Braun, Ulrich vor dem Esche, Georg Häcker, Marcus M. Mücke, Marlene Reincke, Michael Schultheiss, Robert Thimme, Siegbert Rieg, Dominik Bettinger, Lukas Sturm   +13 more
wiley   +1 more source

Management of Gram‐Negative Bloodstream Infections With Oral Antibiotics in Solid Organ Transplant Recipients

Clinical Transplantation, Volume 40, Issue 6, June 2026.
ABSTRACT Background Transitioning from intravenous (IV) to oral antibiotics upon clinical stability in gram‐negative rod (GNR) bloodstream infections (BSI) in immunocompetent patients is effective, with comparable clinical success rates as IV therapy. Studies have historically excluded solid organ transplant (SOT) recipients.
Olubusola Fowowe, Taylor Morrisette, Aaron Hamby, Krutika Mediwala Hornback, Kelsey Coffman, Lindsay Deloney, Rodericks Fobbs, Alexandra Mills, Courtney Harris, Rachel Burgoon   +9 more
wiley   +1 more source

Effects of Nacubactam and Its Metabolites on QTc Interval: A Pooled Analysis of Two Randomized Phase 1 Studies

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Nacubactam is a β‐lactamase inhibitor. Early‐phase studies with 1000/2000/4000/8000 mg nacubactam monotherapy were not powered to assess proarrhythmic risk. Therefore, this analysis pooled electrocardiogram data from two placebo‐controlled studies to quantify potential effects of nacubactam on cardiac repolarization.
Jun Morita, Sue McKendrick, Yuji Kumagai
wiley   +1 more source

β-Lactamase-Producing <i>Haemophilus influenzae</i> Pneumonia in a 1-Month-Old Infant With Respiratory Syncytial Virus Bronchiolitis. [PDF]

J Gen Fam Med
Zensho K, Nojima N, Hino R, Isse N.
europepmc   +1 more source

Exploring the Antimicrobial Efficacy of Mesenchymal Stem Cell Secretome Against Klebsiella pneumoniae in Urinary Tract Infections

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Antimicrobial resistance (AMR) has become a global health crisis, with Klebsiella pneumoniae (K. pneumoniae) emerging as a major driver of AMR and a leading cause of urinary tract infections (UTIs). Mesenchymal stem cell (MSC)‐derived secretomes have gained attention for their antimicrobial properties.
Leen Ali, Elie Salem Sokhn, Charbel Khalil, Fatima A. Saleh   +3 more
wiley   +1 more source

Characterization of the novel class A β-Lactamase gene bla_KOB-1 in an Enterobacter isolate. [PDF]

BMC Microbiol
Zhao J, Yue Q, Lu J, Song C, Zhang Y, Liu C, Bao Q, Xu T, Zhang H, Zhang X.   +9 more
europepmc   +1 more source

S1‐Leitlinie Infizierte Zehenzwischenraum‐Intertrigo (sogenannter „gramnegativer Fußinfekt“)

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 6, Page 832-845, June 2026.
Zusammenfassung Die infizierte Zehenzwischenraum‐Intertrigo bezeichnet eine exsudative, mazerierende oberflächliche Mischinfektion der Zehenzwischenräume, bei der gramnegative Bakterien (vor allem Pseudomonas aeruginosa, Enterobacterales) hervorstechen, aber regelmäßig auch grampositive Erreger (Staphylococcus [S.] aureus, koagulasenegative ...
Christoph Zeyen, Dietrich Abeck, Karsten Becker, Joachim Dissemond, Birgit Kahle, Hans Peter Lorenzen, Bettina Löffler, Andreas Maier‐Hasselmann, Till Mittank‐Weidner, Alexander Nast, Cord Sunderkötter   +10 more
wiley   +1 more source

<i>In vitro</i> activity of the novel β-lactamase inhibitor nacubactam against a nationwide collection of carbapenem-resistant Enterobacterales in Japan. [PDF]

JAC Antimicrob Resist
Yanagihara K, Tateda K, Doi Y, Takahashi S, Ohge H, Itahashi K, Okade H, Mikamo H.   +7 more
europepmc   +1 more source

S1 Guideline on Infected Interdigital Intertrigo (also called Gram‐Negative Toe Web Infection)

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 6, Page 832-843, June 2026.
Summary Infected interdigital intertrigo is an exudative, macerating, mixed infection of the toe webs in which gram‐negative bacteria (Pseudomonas aeruginosa and Enterobacterales) seem prevalent, but in which gram‐positive pathogens (Staphylococcus [S.] aureus, streptococci, enterococci) and fungi (dermatophytes, yeasts) also occur.
Christoph Zeyen, Dietrich Abeck, Karsten Becker, Joachim Dissemond, Birgit Kahle, Hans Peter Lorenzen, Bettina Löffler, Andreas Maier‐Hasselmann, Till Mittank‐Weidner, Alexander Nast, Cord Sunderkötter   +10 more
wiley   +1 more source