Cryptic Binding Pockets in PDC‑3 β‑Lactamase Modulate Resistance Profiles. [PDF]
Chen S +6 more
europepmc +1 more source
A Semester-Long Laboratory in Molecular Biology and Biochemistry Focusing on the Discovery of Novel β-Lactamase Inhibitors From Streptomyces. [PDF]
Gordon MT +3 more
europepmc +1 more source
ABSTRACT Introduction Klebsiella pneumoniae is a pathogen associated with healthcare‐acquired infections and antimicrobial resistance (AMR) to beta‐lactams and carbapenems. Although wild animals are not typically exposed to antibiotics, they can harbour resistant strains. The European hedgehog (Erinaceus europaeus) is increasingly found in urban areas,
Biel Garcias +5 more
wiley +1 more source
First identification and molecular characterization of CTX-M-15 extended-spectrum β-lactamase and OXA-9 β-lactamase in <i>Haemophilus influenzae</i> in the Iberian Peninsula. [PDF]
González-Díaz A +7 more
europepmc +1 more source
Approved zinc‐binding drugs and newly synthesized HisPyr ligands were evaluated as adjuvants to meropenem against metallo‐β‐lactamase‐producing Klebsiella pneumoniae. Chlorpropamide and D‐penicillamine restored meropenem activity against the VIM‐1‐producing strain, while computational analyses supported interactions with the enzyme's binuclear zinc ...
Chiara Ragusa +6 more
wiley +1 more source
Chemical Composition, Antioxidant Activity, and β-Lactamase Inhibitory Potential of Essential Oil from <i>Micromelum falcatum</i> (Lour.) Tanaka. [PDF]
Zhang Y, Li Z, Du Z, Wang Z, Liu X.
europepmc +1 more source
Reduced catalytic activity of KPC β-lactamase can increase ceftazidime resistance. [PDF]
Birgy A +7 more
europepmc +1 more source
Characterization of the intrinsic AmpC β-lactamase of Escherichia marmotae and its impact on decreased susceptibility to cefiderocol and resistance to broad-spectrum cephalosporins. [PDF]
Freire S +5 more
europepmc +1 more source
Retrospective evaluation of the effectiveness of flomoxef against infections with extended-spectrum β-lactamase-producing <i>Enterobacterales</i>. [PDF]
Koizumi R +4 more
europepmc +1 more source

