Results 31 to 40 of about 935,518 (288)

Contributions of β-lactamase substrate specificity and outer membrane permeability to the antibiotic sheltering of β-lactam-susceptible bacteria [PDF]

RSC Chemical Biology
The use of β-lactam antibiotics is threatened by antibiotic resistant bacteria that produce β-lactamases. These enzymes not only protect the bacteria that produce them but also shelter other bacteria in the same environment that would otherwise be ...
Montserrat Mora-Ochomogo, Mitchell A. Jeffs, Josephine L. Liu, Christopher T. Lohans   +3 more
doaj   +1 more source

Hinge-shift mechanism as a protein design principle for the evolution of β-lactamases from substrate promiscuity to specificity

Nature Communications, 2021
TEM-1 β-lactamase evolved from ancestral enzymes that degraded a variety of β-lactam antibiotics with moderate efficiency and degrades β-lactam antibiotics with a strong preference for penicillins.
Tushar Modi, Valeria A. Risso, Sergio Martinez-Rodriguez, Jose A. Gavira, Mubark D. Mebrat, Wade D. Van Horn, Jose M. Sanchez-Ruiz, S. Banu Ozkan   +7 more
doaj   +1 more source

In Vitro Susceptibility of Aztreonam-Vaborbactam, Aztreonam-Relebactam and Aztreonam-Avibactam Associations against Metallo-β-Lactamase-Producing Gram-Negative Bacteria

Antibiotics, 2023
Background: Despite the availability of new options (ceftazidime-avibactam, imipenem-relebactam, meropenem-vaborbactam and cefiderocol), it is still very difficult to treat infections caused by metallo-β-lactamase (MBLs)-producers resistant to aztreonam.
Cécile Emeraud, Sandrine Bernabeu, Laurent Dortet   +2 more
doaj   +1 more source

Image_1_Exploring broilers and native fowls of Andaman and Nicobar Islands as a source of β-lactamase-producing Enterobacteriaceae even with limited anthropogenic activities and docking-based identification of catalytic domains in novel β-lactamase variants.JPEG

, 2023
ObjectivesThe present study was conducted to detect the occurrence of β-lactamase and biofilm-producing Escherichia coli, Salmonella, and Klebsiella in broilers and native fowl reared in the Andaman and Nicobar Islands, India.
Sneha Bhowmick (14330862), Tapan Kumar Dutta (14330880), Abhishek D. Singh (14330871), Siddhartha Narayan Joardar (14330874), Ananda Tiwari (7422383), Indranil Samanta (14330883), Surajit Pal (14330865), Kunal Batabyal (14330877), Jai Sunder (10119897), Samiran Bandyopadhyay (12880697), T. Sujatha (10119894), Tousif Mondal (14330868), Arun Kumar De (10119885)   +12 more
core   +1 more source

Image_9_Exploring broilers and native fowls of Andaman and Nicobar Islands as a source of β-lactamase-producing Enterobacteriaceae even with limited anthropogenic activities and docking-based identification of catalytic domains in novel β-lactamase variants.JPEG

, 2023
ObjectivesThe present study was conducted to detect the occurrence of β-lactamase and biofilm-producing Escherichia coli, Salmonella, and Klebsiella in broilers and native fowl reared in the Andaman and Nicobar Islands, India.
Sneha Bhowmick (14330862), Tapan Kumar Dutta (14330880), Abhishek D. Singh (14330871), Siddhartha Narayan Joardar (14330874), Ananda Tiwari (7422383), Indranil Samanta (14330883), Surajit Pal (14330865), Kunal Batabyal (14330877), Jai Sunder (10119897), Samiran Bandyopadhyay (12880697), T. Sujatha (10119894), Tousif Mondal (14330868), Arun Kumar De (10119885)   +12 more
core   +1 more source

Detection of cfxA2, cfxA3, and cfxA6 genes in beta-lactamase producing oral anaerobes

Journal of Applied Oral Science, 2016
Purpose The aim of this study was to identify β-lactamase-producing oral anaerobic bacteria and screen them for the presence of cfxA and BlaTEM genes that are responsible for β-lactamase production and resistance to β-lactam antibiotics.
Buhle BINTA, Mrudula PATEL
doaj   +1 more source

Molecular Docking Approach of Viscosin as Antibacterial for Methicillin-resistant Staphylococcus Aureus Via β-Lactamase Inhibitor Mechanism

Clinical and Research Journal in Internal Medicine, 2021
Background: β-lactamase is an enzyme that plays a role in the occurrence of antibiotic resistance against Methicillin-resistant Staphylococcus aureus (MRSA) bacteria. Viscosin is a lipopeptide biosurfactant produced by the Pseudomonas group bacteria.
Mokhamad Fahmi Rizki Syaban, Nabila Erina Erwan, Muhammad Rafif Raihan Syamsuddin, Fatimah Az Zahra, Faradilah Lukmana Sabila   +4 more
openaire   +1 more source

Image_6_Exploring broilers and native fowls of Andaman and Nicobar Islands as a source of β-lactamase-producing Enterobacteriaceae even with limited anthropogenic activities and docking-based identification of catalytic domains in novel β-lactamase variants.JPEG

, 2023
ObjectivesThe present study was conducted to detect the occurrence of β-lactamase and biofilm-producing Escherichia coli, Salmonella, and Klebsiella in broilers and native fowl reared in the Andaman and Nicobar Islands, India.
Sneha Bhowmick (14330862), Tapan Kumar Dutta (14330880), Abhishek D. Singh (14330871), Siddhartha Narayan Joardar (14330874), Ananda Tiwari (7422383), Indranil Samanta (14330883), Surajit Pal (14330865), Kunal Batabyal (14330877), Jai Sunder (10119897), Samiran Bandyopadhyay (12880697), T. Sujatha (10119894), Tousif Mondal (14330868), Arun Kumar De (10119885)   +12 more
core   +1 more source

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Periodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis, Daniel Belstrøm, Sigrun Eick, Ulvi K. Gursoy, Anders Johansson, Eija Könönen   +5 more
wiley   +1 more source

Nucleotide sequence of the gene encoding the active-site serine β-lactamase fromStreptomyces cacaoi [PDF]

FEMS Microbiology Letters, 1988
Abstract The gene encoding the extracellular active-site serine β-lactamase of Streptomyces cacaoi previously cloned into Streptomyces lividans , has the information for the synthesis of a 303 amino-acid precursor. The β-lactamase as excreted by the host S.
Mauro V. Lenzini, Hiroshi Ishihara, Jean Dusart, Hiroshi Ogawara, Bernard Joris, Jozef Beeumen, Jean-Marie Frère, Jean-Marie Ghuysen   +7 more
openaire   +1 more source