Various Extracts of Some Medicinal Plants as Inhibitors for Beta-lactamase Activity
The inhibitory effect of acetone, ethanol, and aqueous extracts of ten medicinal plants on β-lactamase from Staphylococcus sciuri and Klebsiella pneumoniae was investigated in vitro by starch-iodine agar plate method.
Huda S. A. Al-Hayanni, Hamed El-Shora
doaj +1 more source
Distribution of β-lactamase genes of Klebsiella pneumoniae isolates in Zhejiang province, China, and regulation of gene expression [PDF]
Klebsiella pneumoniae is a common causative agent of nosocomial infections with a high level of resistance toward β-lactam antibiotics. Our previous study showed that TEM-1 and SHV-11 are the predominant β-lactamase-encoding genes of K ...
Zhao Jin-Fang +5 more
doaj +1 more source
Virulence of non-β-lactamase-mediated ampicilin-resistantHaemophilus influenzae [PDF]
We questioned whether strains of ampicillin-resistant, non-β-lactamase-producing (AmpR NBLP) Haemophilus influenae with lower affinity penicillin-binding proteins (PBPs) might have altered virulence. The virulence of resistant transformant strains and the susceptible recipient was compared using infant rats. Following intraperitoneal inoculation, there
Lorry G. Rubin +3 more
openaire +1 more source
LXA-1: a new plasmid-mediated β-lactamase giving low-level resistance [PDF]
LXA-1, a novel plasmid-mediated β-lactamase, was observed in clinical isolates of Klebsiella oxytoca, Klebsiella pneumoniae, Citrobacter freundii and Enterobacter cloacae. All the strains additionally produced TEM-1 β-lactamase. LXA-1 had an Mr of 24 000 and a pI of 6.7.
Youjun Yang, G.A. Jacoby, D.M. Livermore
openaire +1 more source
Fluorescent Mesoporous Nanoparticles for β‐Lactamase Screening Assays
We present a sensitive and rapid screening method for the determination of β‐lactamase activity of antibiotic‐resistant bacteria, by designing a pH‐sensitive fluorescent dye‐doped mesoporous silica nanoparticle encapsulated with penicillin G as a ...
Srikrishna Tummala +4 more
doaj +1 more source
PREVALENCE OF Β- LACTAMASE PRODUCING STAPHYLOCOCCUS AUREUS IN SLAUGHTERED [PDF]
Fifty liver and lung samples (25 for each) were examend for the presence of Staphylococcus aureus . The rate of S. aureus isolates were 60 and 56% in livers and lungs respectively. Identification of S.
Adnan M. AL- Rodhan
doaj +1 more source
Prevalence of 16S rRNA methylase genes among β-lactamase-producing Enterobacteriaceae clinical isolates in Saudi Arabia [PDF]
Background: Co production of 16S rRNA methylases gene and β-Lactamase gene among Enterobacteriaceae isolates conferring resistance to both therapeutic options has serious implications for clinicians worldwide.
Yazeed A. Al Sheikh +4 more
doaj +1 more source
The Mechanisms of Catalysis by Metallo β-Lactamases [PDF]
Class B β-lactamases or metallo-β-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of β-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins.
Michael I. Page +3 more
core +1 more source
β-lactam antibiotics are the most widely used antimicrobial agents since the discovery of benzylpenicillin in the 1920s. Unfortunately, these life-saving antibiotics are vulnerable to inactivation by continuously evolving β-lactamase enzymes that are ...
Nousheen Parvaiz +4 more
doaj +1 more source
High colonization rates of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli [PDF]
BACKGROUND International travel contributes to the worldwide spread of multidrug resistant Gram-negative bacteria. Rates of travel-related faecal colonization with extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae vary for different ...
Battegay, Manuel +25 more
core +1 more source

