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Various Extracts of Some Medicinal Plants as Inhibitors for Beta-lactamase Activity

open access: yesمجلة بغداد للعلوم, 2021
The inhibitory effect of acetone, ethanol, and aqueous extracts of ten medicinal plants on β-lactamase from Staphylococcus sciuri and Klebsiella pneumoniae was investigated in vitro by starch-iodine agar plate method.
Huda S. A. Al-Hayanni, Hamed El-Shora
doaj   +1 more source

Distribution of β-lactamase genes of Klebsiella pneumoniae isolates in Zhejiang province, China, and regulation of gene expression [PDF]

open access: yesArchives of Biological Sciences, 2017
Klebsiella pneumoniae is a common causative agent of nosocomial infections with a high level of resistance toward β-lactam antibiotics. Our previous study showed that TEM-1 and SHV-11 are the predominant β-lactamase-encoding genes of K ...
Zhao Jin-Fang   +5 more
doaj   +1 more source

Virulence of non-β-lactamase-mediated ampicilin-resistantHaemophilus influenzae [PDF]

open access: yesFEMS Microbiology Letters, 1991
We questioned whether strains of ampicillin-resistant, non-β-lactamase-producing (AmpR NBLP) Haemophilus influenae with lower affinity penicillin-binding proteins (PBPs) might have altered virulence. The virulence of resistant transformant strains and the susceptible recipient was compared using infant rats. Following intraperitoneal inoculation, there
Lorry G. Rubin   +3 more
openaire   +1 more source

LXA-1: a new plasmid-mediated β-lactamase giving low-level resistance [PDF]

open access: yesFEMS Microbiology Letters, 1988
LXA-1, a novel plasmid-mediated β-lactamase, was observed in clinical isolates of Klebsiella oxytoca, Klebsiella pneumoniae, Citrobacter freundii and Enterobacter cloacae. All the strains additionally produced TEM-1 β-lactamase. LXA-1 had an Mr of 24 000 and a pI of 6.7.
Youjun Yang, G.A. Jacoby, D.M. Livermore
openaire   +1 more source

Fluorescent Mesoporous Nanoparticles for β‐Lactamase Screening Assays

open access: yesChemistryOpen, 2020
We present a sensitive and rapid screening method for the determination of β‐lactamase activity of antibiotic‐resistant bacteria, by designing a pH‐sensitive fluorescent dye‐doped mesoporous silica nanoparticle encapsulated with penicillin G as a ...
Srikrishna Tummala   +4 more
doaj   +1 more source

PREVALENCE OF Β- LACTAMASE PRODUCING STAPHYLOCOCCUS AUREUS IN SLAUGHTERED [PDF]

open access: yesBasrah Journal of Veterinary Research, 2008
Fifty liver and lung samples (25 for each) were examend for the presence of Staphylococcus aureus . The rate of S. aureus isolates were 60 and 56% in livers and lungs respectively. Identification of S.
Adnan M. AL- Rodhan
doaj   +1 more source

Prevalence of 16S rRNA methylase genes among β-lactamase-producing Enterobacteriaceae clinical isolates in Saudi Arabia [PDF]

open access: yesLibyan Journal of Medicine, 2014
Background: Co production of 16S rRNA methylases gene and β-Lactamase gene among Enterobacteriaceae isolates conferring resistance to both therapeutic options has serious implications for clinicians worldwide.
Yazeed A. Al Sheikh   +4 more
doaj   +1 more source

The Mechanisms of Catalysis by Metallo β-Lactamases [PDF]

open access: yes, 2008
Class B β-lactamases or metallo-β-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of β-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins.
Michael I. Page   +3 more
core   +1 more source

Discovery of beta-lactamase CMY-10 inhibitors for combination therapy against multi-drug resistant Enterobacteriaceae.

open access: yesPLoS ONE, 2021
β-lactam antibiotics are the most widely used antimicrobial agents since the discovery of benzylpenicillin in the 1920s. Unfortunately, these life-saving antibiotics are vulnerable to inactivation by continuously evolving β-lactamase enzymes that are ...
Nousheen Parvaiz   +4 more
doaj   +1 more source

High colonization rates of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli [PDF]

open access: yes, 2014
BACKGROUND International travel contributes to the worldwide spread of multidrug resistant Gram-negative bacteria. Rates of travel-related faecal colonization with extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae vary for different ...
Battegay, Manuel   +25 more
core   +1 more source

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