Effect of β-Lactamase inhibitors on in vitro activity of β-Lactam antibiotics against Burkholderia cepacia complex species [PDF]
Antimicrobial Resistance and Infection Control, 2016 Background Bacteria belonging to the Burkholderia cepacia complex (Bcc) are an important cause of chronic respiratory tract infections in cystic fibrosis patients.
Annelien Everaert, Tom Coenye
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PREVALENCE OF Β- LACTAMASE PRODUCING STAPHYLOCOCCUS AUREUS IN SLAUGHTERED [PDF]
Basrah Journal of Veterinary Research, 2008 Fifty liver and lung samples (25 for each) were examend for the presence of Staphylococcus aureus . The rate of S. aureus isolates were 60 and 56% in livers and lungs respectively. Identification of S.
Adnan M. AL- Rodhan
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Identification and characterization of a novel β-lactamase TLE-2, encoded by plasmid pUK702 [PDF]
FEMS Microbiology Letters, 1987 A novel plasmid-mediated β-lactamase has been identified in a Klebsiella pneumoniae strain, carried by a plasmid pUK702. The pUK702 plasmid encodes TEM-1 and SHV-1 β-lactamase enzymes in addition to the novel enzyme. The novel enzyme has an Mr of 19 000 and a pI of 6.5. The enzyme is TEM-like in substrate profile and has been designated TLE-2 (TEM-like
Alison J. Reid +3 more
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Fluorescent Mesoporous Nanoparticles for β‐Lactamase Screening Assays
ChemistryOpen, 2020 We present a sensitive and rapid screening method for the determination of β‐lactamase activity of antibiotic‐resistant bacteria, by designing a pH‐sensitive fluorescent dye‐doped mesoporous silica nanoparticle encapsulated with penicillin G as a ...
Srikrishna Tummala +4 more
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Prevalence of 16S rRNA methylase genes among β-lactamase-producing Enterobacteriaceae clinical isolates in Saudi Arabia [PDF]
Libyan Journal of Medicine, 2014 Background: Co production of 16S rRNA methylases gene and β-Lactamase gene among Enterobacteriaceae isolates conferring resistance to both therapeutic options has serious implications for clinicians worldwide.
Yazeed A. Al Sheikh +4 more
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PLoS ONE, 2021 β-lactam antibiotics are the most widely used antimicrobial agents since the discovery of benzylpenicillin in the 1920s. Unfortunately, these life-saving antibiotics are vulnerable to inactivation by continuously evolving β-lactamase enzymes that are ...
Nousheen Parvaiz +4 more
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Isolation and preliminary characterization of β-lactamase excretory mutants ofEscherichia coliK-12 [PDF]
FEMS Microbiology Letters, 1984 Abstract Escherichia coli exc mutants able to release the plasmid pBR322-encoded β-lactamase (EC 3.5.2.6) into the extracellular medium have been isolated using a new in situ plate assay. A preliminary characterization of the exc mutants was carried out: the presence of exc mutations was associated with a specific or pleiotropic pattern of ...
Nicole Fognini-Lefebvre +1 more
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Deactivation of TEM-1 beta-Lactamase investigated by isothermal batch and non-isothermal continuous enzyme membrane reactor methods [PDF]
, 2009 The thermal deactivation of TEM-1 β-lactamase was examined using two experimental techniques: a series of isothermal batch assays and a single, continuous, non-isothermal assay in an enzyme membrane reactor (EMR).
Bommarius, Andreas S. +2 more
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Rapid optical determination of β-lactamase and antibiotic activity [PDF]
, 2014 Background: The absence of rapid tests evaluating antibiotic susceptibility results in the empirical prescription of antibiotics. This can lead to treatment failures due to escalating antibiotic resistance, and also furthers the emergence of drug ...
Hasan, Tayyaba +4 more
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A zinc finger protein array for the visual detection of specific DNA sequences for diagnostic applications. [PDF]
, 2010 The visual detection of specific double-stranded DNA sequences possesses great potential for the development of diagnostics. Zinc finger domains provide a powerful scaffold for creating custom DNA-binding proteins that recognize specific DNA sequences ...
Kim, Moon-Soo +4 more
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