Results 171 to 180 of about 37,330 (229)

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Management of Gram‐Negative Bloodstream Infections With Oral Antibiotics in Solid Organ Transplant Recipients

Clinical Transplantation, Volume 40, Issue 6, June 2026.
ABSTRACT Background Transitioning from intravenous (IV) to oral antibiotics upon clinical stability in gram‐negative rod (GNR) bloodstream infections (BSI) in immunocompetent patients is effective, with comparable clinical success rates as IV therapy. Studies have historically excluded solid organ transplant (SOT) recipients.
Olubusola Fowowe, Taylor Morrisette, Aaron Hamby, Krutika Mediwala Hornback, Kelsey Coffman, Lindsay Deloney, Rodericks Fobbs, Alexandra Mills, Courtney Harris, Rachel Burgoon   +9 more
wiley   +1 more source

Integrating Siderophore Substructures in Thiol-Based Metallo-β-Lactamase Inhibitors. [PDF]

Molecules, 2023
Rotter MJ, Zentgraf S, Weizel L, Frank D, Burgers LD, Brunst S, Fürst R, Proschak A, Wichelhaus TA, Proschak E.   +9 more
europepmc   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Effects of Nacubactam and Its Metabolites on QTc Interval: A Pooled Analysis of Two Randomized Phase 1 Studies

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Nacubactam is a β‐lactamase inhibitor. Early‐phase studies with 1000/2000/4000/8000 mg nacubactam monotherapy were not powered to assess proarrhythmic risk. Therefore, this analysis pooled electrocardiogram data from two placebo‐controlled studies to quantify potential effects of nacubactam on cardiac repolarization.
Jun Morita, Sue McKendrick, Yuji Kumagai
wiley   +1 more source

Navigating the complexities of drug development for metallo-β-lactamase inhibitors. [PDF]

RSC Med Chem
Reddy N, Balieiro AM, Silva JRA, Gouws CA, Mutshembele A, Arvidsson PI, Kruger HG, Govender T, Naicker T.   +8 more
europepmc   +1 more source

Synthesis and biological evaluation of novel β-lactam-metallo β-lactamase inhibitors. [PDF]

RSC Adv, 2023
Shungube M, Hlophe AK, Girdhari L, Sabe VT, Peters BB, Reddy N, Omolabi KF, Chetty L, Arumugam T, Chuturgoon A, Kruger HG, Arvidsson PI, Qin HL, Naicker T, Govender T.   +14 more
europepmc   +1 more source

Exploring the Antimicrobial Efficacy of Mesenchymal Stem Cell Secretome Against Klebsiella pneumoniae in Urinary Tract Infections

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Antimicrobial resistance (AMR) has become a global health crisis, with Klebsiella pneumoniae (K. pneumoniae) emerging as a major driver of AMR and a leading cause of urinary tract infections (UTIs). Mesenchymal stem cell (MSC)‐derived secretomes have gained attention for their antimicrobial properties.
Leen Ali, Elie Salem Sokhn, Charbel Khalil, Fatima A. Saleh   +3 more
wiley   +1 more source

Resistance to novel β-lactam/β-lactamase inhibitors among carbapenem-resistant <i>Pseudomonas aeruginosa</i> and clinical implications in the prospective observational <i>Pseudomonas</i> study. [PDF]

Antimicrob Agents Chemother
Gottesdiener LS, Li Y, Greenwood-Quaintance KE, Komarow L, Arias CA, Cober E, Herc ES, Kaye KS, Huskins WC, Figueroa J, Vilchez S, Fries BC, Leroi M, McCarty TP, Rioseco ML, Munita JM, Stryjewski ME, Reyes J, Chen L, Kreiswirth BN, Hill C, Baum K, Villegas MV, Paterson DL, Bonomo RA, Chambers HF, Fowler VG, Patel R, Doi Y, van Duin D, Satlin MJ, Antibacterial Resistance Leadership Group.   +31 more
europepmc   +1 more source

S1 Guideline on Infected Interdigital Intertrigo (also called Gram‐Negative Toe Web Infection)

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 6, Page 832-843, June 2026.
Summary Infected interdigital intertrigo is an exudative, macerating, mixed infection of the toe webs in which gram‐negative bacteria (Pseudomonas aeruginosa and Enterobacterales) seem prevalent, but in which gram‐positive pathogens (Staphylococcus [S.] aureus, streptococci, enterococci) and fungi (dermatophytes, yeasts) also occur.
Christoph Zeyen, Dietrich Abeck, Karsten Becker, Joachim Dissemond, Birgit Kahle, Hans Peter Lorenzen, Bettina Löffler, Andreas Maier‐Hasselmann, Till Mittank‐Weidner, Alexander Nast, Cord Sunderkötter   +10 more
wiley   +1 more source