Results 171 to 180 of about 1,471,936 (197)

In-vitro activity of newly-developed β-lactamase inhibitors avibactam, relebactam and vaborbactam in combination with anti-pseudomonal β-lactam antibiotics against AmpC-overproducing clinical Pseudomonas aeruginosa isolates. [PDF]

Eur J Clin Microbiol Infect Dis
Le Terrier C, Raro OHF, Saad AM, Nordmann P, Poirel L.   +4 more
europepmc   +1 more source

Hydroxyhexylitaconic acids as potent IMP-type metallo-β-lactamase inhibitors for controlling carbapenem resistance in <i>Enterobacterales</i>. [PDF]

Microbiol Spectr
Wachino J-i, Jin W, Norizuki C, Kimura K, Tsuji M, Kurosaki H, Arakawa Y.   +6 more
europepmc   +1 more source

Antimicrobial and Diagnostic Stewardship of the Novel β-Lactam/β-Lactamase Inhibitors for Infections Due to Carbapenem-Resistant Enterobacterales Species and Pseudomonas aeruginosa. [PDF]

Antibiotics (Basel)
Ferous S, Anastassopoulou C, Pitiriga V, Vrioni G, Tsakris A.   +4 more
europepmc   +1 more source

Assessment of the activity and mechanisms of resistance to cefiderocol and combinations of β-lactams and the novel β-lactamase inhibitors avibactam, taniborbactam, zidebactam, nacubactam, xeruborbactam, and ANT3310 in emerging double-carbapenemase-producing Enterobacterales. [PDF]

Antimicrob Agents Chemother
Blanco-Martín T, López-Hernández I, Aracil B, González-Pinto L, Aja-Macaya P, Alonso-García I, Rodríguez-Pallares S, Sánchez-Peña L, Outeda-García M, Pérez-Vázquez M, Vázquez-Ucha JC, Beceiro A, Pascual Á, Bou G, López-Cerero L, Oteo-Iglesias J, Arca-Suárez J, GEMARA-SEIMC/CIBERINFEC Study Group on the activity and resistance mechanisms to new β-lactams and β-lactamase inhibitors (PROTECT).   +17 more
europepmc   +1 more source

Development and Validation of a Capillary Zone Electrophoresis-Tandem Mass Spectrometry Method for Simultaneous Quantification of Eight β-Lactam Antibiotics and Two β-Lactamase Inhibitors in Plasma Samples. [PDF]

Pharmaceuticals (Basel)
Cizmarova I, Mikus P, Svidrnoch M, Piestansky J.   +3 more
europepmc   +1 more source

Multigram-scale chemoenzymatic synthesis of diverse aminopolycarboxylic acids as potential metallo-β-lactamase inhibitors.

Org Biomol Chem
Bhat MF, Prats Luján A, Saifuddin M, Fodran P, Poelarends GJ.   +4 more
europepmc   +1 more source

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An Extensive Review on β-lactamase Enzymes and their Inhibitors

Current Medicinal Chemistry, 2023
Pritish Varadwaj, Akhilesh Tiwari
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β-Lactam Antibiotics and β-Lactamase Enzymes Inhibitors, Part 2: Our Limited Resources

Pharmaceuticals, 2022
Silvana Alfei, Anna Maria Schito
exaly