Results 151 to 160 of about 37,330 (229)

The in vitro effect of new combinations of carbapenem-β-lactamase inhibitors for Mycobacterium abscessus. [PDF]

Antimicrob Agents Chemother, 2023
Fröberg G, Ahmed A, Chryssanthou E, Davies Forsman L.   +3 more
europepmc   +1 more source

Detection and Characterization of ESBL‐Producing and Carbapenem‐Resistant Klebsiella pneumoniae in Ornamental Birds and Their Surrounding Environments

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Multidrug‐resistant ESBL‐ and carbapenem‐resistant Klebsiella pneumoniae were identified from ornamental birds, their handlers and surrounding environments, carrying key virulence and resistant genes, highlighting potential One Health transmission risks between animals, humans and the associated environments.
Md Abdullah Evna Hasan, Md. Liton Rana, Md Saiful Islam, Sadia Afrin Punom, Md. Tabeer Hossain Antor, Diruba Akter Jany, Naeem Ahammed Ibrahim Fahim, S M Abu Sama Al Faruquee, Md. Raisul Islam, Zuhayr Bakhtiyar, Anindita Ash Prome, Md. Monirul Islam, Saifur Rahman, Mohammad Ferdousur Rahman Khan, Md. Tanvir Rahman   +14 more
wiley   +1 more source

Structural and Kinetic Basis for the Rational Design of Next-Generation β-Lactamase Inhibitors. [PDF]

J Med Chem
Chen S, Yu M, Xu M, Decherchi S, Taracila MA, Hujer AM, Bethel CR, Bonomo RA, Haider S.   +8 more
europepmc   +1 more source

Genome‐Guided Discovery of Vaccine Targets for a Multi‐Epitope Construct Against Multidrug‐Resistant Enterobacter cloacae

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Multidrug‐resistance (MDR) Enterobacter cloacae was targeted using a genome wide immunoinformatics approach. Conserved and surface exposed outer membrane protien A (OmpA) was identified as the prime vaccine target following proteome screening, antigenicity, allergenicity, and homology analysis.
Maha A. Aljumaa, Fakhria A. Al‐Joufi, Ghulam Nabi, Mengue Ngadena Yolande Sandrine   +3 more
wiley   +1 more source

Nanjing Consensus II on Washed Microbiota Transplantation: Statements From the CHINAGUT Conference

Microbiota Medicine Research, Volume 1, Issue 2, Page 45-62, June 2026.
ABSTRACT The new method of fecal microbiota transplantation, based on automatic facilities and washing processes, was coined as washed microbiota transplantation (WMT). The first recommendations on WMT were released as Nanjing Consensus report by the fecal microbiota transplantation (FMT)‐standardization Study Group in 2019.
Faming Zhang, Sunny Hei Wong, Gaochen Lu, Zheshun Pi, Ting Zhang, Hon Ho Yu, Nan Bu, Xiong Chen, Bota Cui, Dafa Ding, Hainv Gao, Suyu He, Xingxiang He, Shengjuan Hu, Jia Hu, Yunlian Hu, Xiaomeng Jiang, Jiang Jin, Jingnan Li, Pan Li, Juan Liao, Weiwei Liao, Jiang Liu, Ling Liu, Yaping Liu, Yanyan Liu, Yu Liu, Muhan Lv, Xiangjun Meng, Yongzhan Nie, Qian Ren, Lixuan Sang, Yang Sun, Xiaowen Tang, Liangjing Wang, Wei Wang, Xin Wang, Yanling Wei, Quan Wen, Lihao Wu, Xia Wu, Fang Xiao, Lijing Xiong, Shaoqi Yang, Song Yang, Guoliang Ye, Yue Zeng, Huihong Zhai, Xiaoqian Zhang, Yu Zhang, Kun Zhao, Li Zhou, Li Zhu, Kaichun Wu   +53 more
wiley   +1 more source

Development of Water-Trapping Pyrrole-2-carboxylic Acids as Broad-Spectrum Metallo-β-lactamase Inhibitors. [PDF]

J Med Chem
Singha M, Wilson LA, C M Moura EC, Trush MM, Calvopina K, Kaur G, Zaborskytė G, Kalniņš T, Panduwawala T, Bowen MJ, Beech MJ, Brem J, McHugh PJ, Suna E, Walsh TR, Schofield CJ, Farley AJM.   +16 more
europepmc   +1 more source

Liquid Chromatography‐Electrospray Ionization‐Tandem Mass Spectrometry Profiling, Antioxidant, Antibacterial, and Antidiabetic Properties of Fagonia cretica L.: Insights From In Vitro and In Silico Approaches

ChemistryOpen, Volume 15, Issue 6, June 2026.
Fagonia cretica L.: Phytochemical investigation and exploration of bioactivity through in vitro and in silico approaches. This study provides an integrative evaluation of the aqueous extract of Fagonia cretica L., a species long employed in traditional medicine but insufficiently characterized through systematic experimental and computational ...
Neghmouche Nacer Salah, Elhafnaoui Lanez, Mohammed Larbi Benamor, Ouafa Zouari Ahmed, Yahia Bekkar, Moussa Senigra, Lazhar Bechki, Stefania Garzoli, Touhami Lanez   +8 more
wiley   +1 more source

Design, Synthesis, and Evaluation of β‑Lactamase Inhibitors as Potential Therapeutics for Antimicrobial Resistance. [PDF]

ACS Omega
Batool S, Farid R, Azam SS, Hassan A.
europepmc   +1 more source

Functional dynamics of water in New Delhi metallo‐β‐lactamase catalysis

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Water plays a critical role in the hydrolysis of antibiotics by New Delhi metallo‐β‐lactamases (NDMs). The reaction proceeds through a nucleophilic attack on the β‐lactam ring, followed by cleavage of the C–N bond and formation of an anionic nitrogen intermediate. This intermediate is then protonated by a water molecule diffusing from the bulk
Palanisamy Kandhan, Chuanye Xiong, Timothy Palzkill, Peng Tao   +3 more
wiley   +1 more source

Data-driven design and screening of novel <i>Klebsiella pneumoniae</i> carbapenemase-2 β-lactamase inhibitors using a generative CLM. [PDF]

RSC Adv
Tariq SS, Haleem MS, Uddin R.
europepmc   +1 more source