Results 141 to 150 of about 37,330 (229)

When First‐Line Therapies Fail: Surgical Site Infections and the Declining Antimicrobial Utility in a Resource‐Limited Nation

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
In Belize, a 7‐year nationwide study reveals a sharp rise in antimicrobial resistance in surgical infections. ESBL‐producing bacteria more than doubled to > 45%, with critical treatment gaps and geographic hotspots identified. Sentinel pan‐drug‐resistant cases and a correlation between antibiotic use and resistance underscore the urgent need for ...
Innocent E. Nwachukwu, Cary W. Rivera, Vivian M. Reyes, Diomar Salazar, Lydia Harris‐Thurton, Danladi C. Husaini   +5 more
wiley   +1 more source

Nanoparticle‐Based Strategies to Combat Multidrug‐Resistant Bacteria: Mechanisms, Applications, and Future Perspectives

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Nanobiotics offer a promising strategy to combat antimicrobial resistance (AMR) and multidrug‐resistant (MDR) bacteria. Nanoparticles overcome traditional resistance mechanisms through unique physicochemical properties and multivalent interactions.
Akmal Zubair, Syeda Zaira Batool, Mohamed H. Helal, Naila Afghan   +3 more
wiley   +1 more source

Hospital‐Associated Antimicrobial Resistant Bacteria on 95 Mobile Phones: An International Metagenomic “Phonome” Analysis

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
On average, phones harbored 3.62 of the top 10 killers and 2.49 ESKAPE organisms. In total, 667 VFGs (8621 Hits) and 262 ARGs (2475 Hits) were identified on 95 mobile phones. Mobile phones serve as a platform for horizontal gene transfer and AMR development.
Adrian Goldsworthy, Matthew Olsen, Nchafatso G. Obonyo, Peter Jones, Simon McKirdy, Abiola Senok, Rashed Alghafri, Rose Ghemrawi, Reem Almheiri, Oystein Tronstad, Jacky Y. Suen, John F. Fraser, Lotti Tajouri   +12 more
wiley   +1 more source

Gut Microbiota Alterations Associated With Colonization by Multidrug‐Resistant Organisms in ICU Patients: First Systematic Review and Meta‐Analysis

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Microbiota profiling showed colonized critically ill patients had lower values of dominance/evenness (Simpson's index) and richness (Observed), reaching significantly lower values of information (mean difference in Shannon index = –1.18; 95% CI, –1.84 to –0.52; p < 0.001).
Andra‐Elena Goicea, Daniel‐Corneliu Leucuța, Constantin Bodolea   +2 more
wiley   +1 more source

The Landscape of Salmonella enterica Serovar Gallinarum–Pullorum Antimicrobial Resistance in Bangladesh's Poultry Industry: A Combined Phenotypic and Molecular Study

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Salmonella enterica serovar Gallinarum–Pullorum isolated from chickens reveals a critical 89.13% prevalence of multidrug resistance. High phenotypic resistance to amoxicillin and tetracycline is genetically underpinned by a robust presence of resistance‐conferring genes (notably tetA, sul1, and blaCMY), highlighting a significant zoonotic threat to ...
Md. Masuk Rahman Kingshuk, Shanzida Binte Alam, Md. Shajedur Rahman, Md. Nurnoby Islam   +3 more
wiley   +1 more source

Antibiotic Resistance and Biofilm Gene Distribution in Colistin‐Resistant Acinetobacter baumannii

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Multicenter analysis of 144 clinical Acinetobacter baumannii isolates in Iran revealed high MDR/XDR rates and widespread biofilm formation (90.9%). Colistin resistance was linked to pmrAB overexpression, while blaPER‐1 was independently associated with strong biofilm production, highlighting chromosomal resistance mechanisms and biofilm as key drivers ...
Zainab Amer Hatem, Fadhela Nafaa Kafe, Farkad Hawas Musa, Sarah F. Al‐Taie, Nabaa Hisham Ateya, Leqaa Majeed Aziz, Erta Rajabi, Raad N. Hasan   +7 more
wiley   +1 more source

A Search for Novel Antimicrobials and Novel β-Lactamase Inhibitors [PDF]

For almost a century, antibiotics have been used as treatment agents in the combat of infections caused by pathogenic microbes.For a short while, antibiotics were heralded as miracle drugs; their discovery and introduction into the clinic ...
Talbot, Nathan
core  

Inhibition of β-lactamase I from Bacillus cereus by ssDNA.

, 2011
Inhibitors of β-lactamases are important to the treatment of infectious diseases when used in conjunction with a β-lactam antibiotic. Current inhibitors of β-lactamase such as clavulanic acid, sulbactam, and tazobactam perform efficiently overall but due
Foster, Taylor Ann.
core   +1 more source

Prevalence, Antimicrobial Resistance, and Resistance Gene Profiles of Extended‐Spectrum β‐Lactamase‐Producing Escherichia coli and Klebsiella pneumoniae Isolated From Quails in Sylhet, Bangladesh

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
This study investigated the molecular epidemiology and antimicrobial resistance of Escherichia coli and Klebsiella pneumoniae isolated from quails in Bangladesh. High prevalence of E. coli, including Shiga toxin‐producing strains, and widespread multidrug resistance were observed.
Md. Al Mamun, Hemayet Hossain, Md. Shahidur Rahman Chowdhury, Shahida Begum Nargis, Munni Rani Das, Rakibul Hasan, Nasrin Akter Liza, Shuvojit Mitra, Md Bashir Uddin, Md. Mukter Hossain, Md. Mahfujur Rahman   +10 more
wiley   +1 more source

The Role of Neonatal Ward Environment as a Reservoir for the Dissemination of Multidrug‐Resistant Klebsiella pneumoniae in Algeria

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Whole‐genome sequencing of multidrug‐resistant Klebsiella pneumoniae from a neonatal ward environment in Chlef revealed persistent resistance genes and the clonal spread of high‐risk ST13. These findings highlight the hospital environment as a potential reservoir for transmission of resistant K. pneumoniae.
Meriem Derkaoui, Martin Alexander Fischer, Mohammed Sebaihia, Rachida Namoune, Fatiha Bouheudjeur, Meryem Beloukarif, Bakhta Madaoui, Bruno Silvester Lopes   +7 more
wiley   +1 more source