Results 81 to 90 of about 893,542 (154)

Slc12a8 is a nicotinamide mononucleotide transporter

, 2019
Nicotinamide mononucleotide (NMN) is a biosynthetic precursor of NAD+ known to promote cellular NAD+ production and counteract age-associated pathologies associated with a decline in tissue NAD+ levels.
Mills, Kathryn F, Sasaki, Yo, Lei, Hanyue Cecilia, Yoshino, Jun, Tokizane, Kyohei, Imai, Shin-Ichiro, Sociali, Giovanna, Grozio, Alessia, Bruzzone, Santina, Migaud, Marie E, Cunningham, Richard   +10 more
core   +1 more source

Therapeutic effects of combined administration of β-nicotinamide mononucleotide and taurine on experimental silicosis in rats

Zhiye weisheng yu yingji jiuyuan
Objective To investigate the therapeutic effects of β-nicotinamide mononucleotide(β-NMN) and taurine, administered in combination, on experimental silicosis in rats.
GAN Yongjin
doaj   +1 more source

Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH

, 2017
Stimulation of the cytosolic NAD+ dependent deacetylase SIRT1 is cardioprotective against ischemia-reperfusion (IR) injury. NAD+ precursors including nicotinamide mononucleotide (NMN) are thought to induce cardioprotection via SIRT1.
Yves T. Wang, Paul S. Brookes, Sergiy M. Nadtochiy, Joshua Munger, Keith Nehrke   +4 more
core   +1 more source

Grup D β-laktamazlar [PDF]

Class D β-lactamases, according to the Ambler molecular classification, are serine hydrolases like class A and C enzymes. Although evolutionarily related, they share less than 20% homology with classes A and C. Most class D β-lactamases are not inhibited
Hasdemir Gökboğa, Münevver Ufuk
core   +1 more source

NAVIER–STOKES EQUATIONS ON THE β-PLANE [PDF]

, 2012
Mathematical analysis has been undertaken for the vorticity formulation of the two dimensional Navier–Stokes equation on the β-plane with periodic boundary conditions. This equation describes the flow of fluid near the equator of the Earth. The long time
Al-Jaboori, Mustafa Ali Hussain, AL-JABOORI, MUSTAFA,ALI,HUSSAIN   +1 more
core  

Small extracellular vesicles derived from mesenchymal stromal cells loaded with β-nicotinamide mononucleotide activate NAD+/SIRT3 signaling pathway-mediated mitochondrial autophagy to delay skin aging

Stem Cell Research & Therapy
Background Recently, the beneficial effects of human umbilical cord mesenchymal stromal cell (hucMSC)-derived small extracellular vesicles (sEVs) in mitigating skin aging through multiple mechanisms have been widely reported.
Zixuan Sun, Jiali Li, Yuzhou Zheng, Jiaxin Zhang, Wenhuan Bai, Xinyi Deng, Zhijing Wu, XueZhong Xu, Wei Ding, Hui Qian, Yulin Tan   +10 more
doaj   +1 more source

Nicotinamide Mononucleotide: Research Process in Cardiovascular Diseases

Nicotinamide adenine dinucleotide (NAD+) is an essential metabolite that plays a crucial role in diverse biological processes, including energy metabolism, gene expression, DNA repair, and mitochondrial function.
Guang Yang, Ningning Wang, Yu Ma, Haoyuan Deng, Cong Zhang, Hao Zhang, Ding Ding   +6 more
core   +1 more source

Spatial regulation of NMN supplementation on brain lipid metabolism upon subacute and sub-chronic PM exposure in C57BL/6 mice

Particle and Fibre Toxicology
Background Atmospheric particulate matter (PM) exposure-induced neuroinflammation is critical in mediating nervous system impairment. However, effective intervention is yet to be developed.
Yue Jiang, Fang Li, Lizhu Ye, Rui Zhang, Shen Chen, Hui Peng, Haiyan Zhang, Daochuan Li, Liping Chen, Xiaowen Zeng, Guanghui Dong, Wei Xu, Chunyang Liao, Rong Zhang, Qian Luo, Wen Chen   +15 more
doaj   +1 more source

Bioactive Peptide C248 of PRDX4 Ameliorates the Function of Testicular Leydig Cells via Mitochondrial Protection

Antioxidants
Background: The senescence of testicular Leydig cells (LCs) is a key cause of age-related testosterone deficiency, in which oxidative stress (OS) and mitochondrial dysfunction are critical driving mechanisms. We explore whether the bioactive peptide C248
Nini Wei, Shuning Yuan, Li Gao, Bei Zhang, Zhengjie Yan, Chao Gao, Yan Meng, Yugui Cui   +7 more
doaj   +1 more source

β-Nicotinamide mononucleotide alleviates Alcohol-Induced liver injury in a mouse model through activation of NAD+/SIRT1 signaling pathways

Hereditas
Background Alcoholism is a significant contributor to the development of alcoholic liver disease, for which no universally accepted and effective treatment currently exists.
Xinxin Yang, Endian Zheng, Yuxian Lin, Haoyue Sun, Ji Zhang, Yingcong Yu   +5 more
doaj   +1 more source