Results 121 to 130 of about 8,460 (141)

Structural basis of γ-secretase inhibition and modulation by small molecule drugs

Cell, 2021
Guanghui Yang, Rui Zhou, Xuefei Guo
exaly  

Untangling Alzheimer's disease with β-secretase inhibitors

Drug Discovery Today, 2000
openaire   +2 more sources

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

Nature, 2020
Ji-Yeun Hur, Eitan Wong, Marilia Barros
exaly  

γ-Secretase: proteasome of the membrane?

Nature Reviews Molecular Cell Biology, 2004
Raphael Kopan, Ma Xenia G Ilagan
exaly  

Alzheimer’s-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions

Cell, 2017
Maria Szaruga, Bogdan Munteanu, Natalie S Ryan   +2 more
exaly  

β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

Science, 1999
Robert Vassar, David B Teplow, Martin Citron   +2 more
exaly  

Recognition of the amyloid precursor protein by human γ-secretase

Science, 2019
Rui Zhou, Guanghui Yang, Xuefei Guo
exaly  

Purification and cloning of amyloid precursor protein β-secretase from human brain

Nature, 1999
Varghese John
exaly  

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity

Nature, 1999
Michael S Wolfe, Weiming Xia, W Taylor Kimberly   +2 more
exaly  

Structural basis of Notch recognition by human γ-secretase

Nature, 2018
Guanghui Yang, Rui Zhou, Qiang Zhou
exaly