Results 141 to 150 of about 9,562 (190)

Neuroprotective κ-Opioid Receptor Agonist BRL 52537 Attenuates Ischemia-Evoked Nitric Oxide Production In Vivo in Rats [PDF]

, 2003
Toru Goyagi, Thomas J. K. Toung, Jeffrey R. Kirsch, Richard J. Traystman, Raymond C. Koehler, Patricia D. Hurn, Anish Bhardwaj   +6 more
openalex   +1 more source

Identification of c[D-Trp-Phe-β-Ala-β-Ala], the First κ-Opioid Receptor-Specific Negative Allosteric Modulator. [PDF]

ACS Pharmacol Transl Sci
Zhao J, Baiula M, Cuna E, Francescato M, Matalińska J, Lipiński PFJ, Bedini A, Gentilucci L.   +7 more
europepmc   +1 more source

Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain. [PDF]

J Med Chem, 2021
Muratspahić E, Tomašević N, Koehbach J, Duerrauer L, Hadžić S, Castro J, Schober G, Sideromenos S, Clark RJ, Brierley SM, Craik DJ, Gruber CW.   +11 more
europepmc   +1 more source

κ‑opioid receptor agonist U50488H attenuates postoperative cognitive dysfunction of cardiopulmonary bypass rats through the PI3K/AKT/Nrf2/HO‑1 pathway. [PDF]

Mol Med Rep, 2021
Fan J, Li L, Qu P, Diao Y, Sun Y.
europepmc   +1 more source

Down-regulation of the tumour suppressor κ-opioid receptor predicts poor prognosis in hepatocellular carcinoma patients

, 2017
Dongtai Chen, Yonghua Chen, Yan Yan, Jiahao Pan, Wei Xing, Qiang Li, Weian Zeng   +6 more
openalex   +1 more source

LY2444296, a κ-opioid receptor antagonist, selectively reduces alcohol drinking in male and female Wistar rats with a history of alcohol dependence. [PDF]

Sci Rep
Flores-Ramirez FJ, Illenberger JM, Pascasio G, Terenius L, Martin-Fardon R.   +4 more
europepmc   +1 more source

κ‑opioid receptor agonist, U50488H, inhibits pyroptosis through NLRP3 via the Ca²⁺/CaMKII/CREB signaling pathway and improves synaptic plasticity in APP/PS1 mice. [PDF]

Mol Med Rep, 2021
Song X, Cui Z, He J, Yang T, Sun X.
europepmc   +1 more source

κ-Opioid Receptor Is Colocalized in GnRH and KNDy Cells in the Female Ovine and Rat Brain [PDF]

, 2016
Peyton W. Weems, Christine F. Witty, M. Amstalden, Lique M. Coolen, Robert L. Goodman, Michael N. Lehman   +5 more
openalex   +1 more source

κ-Opioid receptor activation attenuates osteoarthritis synovitis by regulating macrophage polarization through the NF-κB pathway. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Shi Y, Tao H, Li X, Zhang L, Li C, Sun W, Chu M, Chen K, Zhu P, Wang Q, Gu C, Wang L, Yang X, Hao Y.   +13 more
europepmc   +1 more source

Enantiomerically Pure Quinoline-Based κ-Opioid Receptor Agonists: Chemoenzymatic Synthesis and Pharmacological Evaluation. [PDF]

ChemMedChem, 2020
Martin B, Schepmann D, Bernal FA, Schmidt TJ, Che T, Loser K, Wünsch B.   +6 more
europepmc   +1 more source