Results 61 to 70 of about 14,532 (113)

[Research on Bacteriophage Resistance: Coevolutionary Arms Race Between Bacteria and Phages Drives Novel Antibacterial Therapies]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Li R, Wan F, Wei J, Wen Y, Jia P, Lin P, Liu L, Wu M.   +7 more
europepmc   +1 more source

IRAK-4基因沉默对人成骨样细胞凋亡的影响

Zhongshan Daxue xuebao. Yixue kexue ban, 2013
【目的】研究siRNA沉默白细胞介素-1受体相关激酶-4(IRAK-4)基因对人成骨样细胞株MG63凋亡及凋亡相关基因Bcl-2、Bax表达的影响。【方法】 以Lipofectamine 2000为载体将IRAK-4-siRNA转染入MG63细胞(CON组:不加入任何转染试剂;SC组:以scrambled siRNA序列进行转染;KD组:以特异性IRAK-4-siRNA序列进行转染),应用流式细胞术及TUNEL法检测细胞凋亡水平,western blotting检测Bcl-2、Bax基因的表达。【结果】
doaj  

[Clinical characteristics of DUX4-IGH fusion B-cell acute lymphoblastic leukemia in children]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Luo YX, Jiang H, Wang JY, Hao WG, Zhang WN.   +4 more
europepmc   +1 more source

PTEN基因对子宫内膜癌细胞PI3K/AKT通路的影响

Zhongshan Daxue xuebao. Yixue kexue ban, 2011
【目的】探讨PTEN基因在子宫内膜癌PI3K/AKT通路中的作用，评估PTEN基因在抗肿瘤治疗中的意义。【方法】利用慢病毒载体系统, 构建人PTEN基因RNA干扰慢病毒载体和PTEN基因过表达慢病毒载体,分别转染PTEN野生型的HEC-1A细胞和PTEN突变型的Ishikawa细胞, 建立PTEN 基因敲减及过表达的细胞模型，Western Blot方法检测PTEN基因敲减或过表达前后PTEN蛋白的表达和AKT通路的活化情况, MTT法检测慢病毒转染前后细胞增殖的变化 ...
doaj  

[EVA1A overexpression improves non-alcoholic fatty liver disease in mice by regulating lipid metabolism and promoting lipophagy]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Xu J, Yang D, Zang K, Chu M, Zhao Q, Li Q, Lu S, Chen X, Li N.   +8 more
europepmc   +1 more source

[A case of toxic shock syndrome secondary to severe bone marrow suppression induced by azathioprine in a patient with autoimmune hepatitis]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Ren Y, Kong M, Huang CY, Bian XQ, Liu HX, Mou DL, Chen Y.   +6 more
europepmc   +1 more source

[Cajanonic acid A derivative XJ-60 improves liver fibrosis in mice with non-alcoholic fatty liver disease by inhibiting the SP1/TGF-β/Smad3 signaling axis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Geng Z, Hu L, Dai Y, Luo R, Xu T, Liao X, Yuan Z, Wang J, Xiao Y.   +8 more
europepmc   +1 more source

[CAR-T cell therapy bridging to allogeneic hematopoietic stem cell transplantation for diffuse large B-cell Richter syndrome: a case report and literature review]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Wang Y, Gao N, Liu ZY, Dong YY, Qin XM, Liu X.   +5 more
europepmc   +1 more source

外源性SHIP基因表达抑制生长因子介导的 K562细胞增殖及Akt磷酸化

Zhongshan Daxue xuebao. Yixue kexue ban, 2009
【目的】 探讨SHIP基因对IL-3诱导K562细胞系增殖的抑制作用,阐明SHIP对K562细胞作用的机制65377;【方法】 将慢病毒质粒pReceiver-Lv31-FIV和pReceiver-Lv31-SHIP转染K562细胞;转染细胞与IL-3共培养,Western blot法检测K562细胞Akt磷酸化;观察转染野生型SHIP基因对K562细胞增殖的影响;末端脱氧核苷酸转移酶介导的dUTP缺失末端标记(TUNEL)法检测细胞凋亡65377;【结果】 重组慢病毒载体pReceiver-Lv31 ...
doaj  

[Quercetin inhibits proliferation and migration and promotes apoptosis of gastric cancer cells by promoting phosphorylation-mediated YAP inactivation]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wang Y, Wang W, Cheng S, Feng Y, Zhang Z, Shi Q, Li Y, Hu Q, Wu M.   +8 more
europepmc   +1 more source