Results 31 to 40 of about 4,208 (163)
Research on the Antidepressive Mechanism of Chaiyuwendan Decoction Based on the Endogenous Cannabinoids system [PDF]
, 2016 目的： 1.观察柴郁温胆汤抗抑郁大鼠模型的药理效应； 2.从内源性大麻素系统探讨柴郁温胆汤抗抑郁的作用机制。 方法： 实验分两部分进行。 1.柴郁温胆汤抗抑郁大鼠模型的药效学实验：实验采用慢性轻度不可预见性应激21天复制大鼠抑郁模型。实验动物分为正常组、模型组、柴郁温胆汤组及氟西汀组，给药21天。观察大鼠体重变化，根据旷场实验和糖水消耗实验观察抑郁模型大鼠的行为学变化；采用Elisa法检测大鼠血清中5-HT、DA、ACTH、CORT的含量；采用酶法检测血清中TG、T-CHO、HDL-C、LDL ...
王宏国
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Wildlife Letters, Volume 3, Issue 2, Page 73-83, June 2025.Blue sheep in Dhorpatan Hunting Reserve prefer alpine grasslands at 3800–4200 m on south‐facing slopes near water resources, favoring areas with low tree cover and dense ground cover, particularly rhododendrons, junipers, and Cyperaceae grasses. Their habitat significantly overlaps with livestock.
Amit Adhikari +4 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2009 目的探讨运动环境干预对低水平铅暴露小鼠海马神经细胞结构影响的特点。方法将离乳后的40只ICR雄性小鼠,随机分为:对照组非运动环境、对照组运动环境和实验组非运动环境、实验组运动环境四组,每组10只各放入76 cm×61 cm×46 cm的笼子内饲养8周。实验组均饮用铅浓度为0.2%的水染毒建模;运动环境是在设有跑车等运动装置下运动。利用原子吸收法进行血铅和脑海马铅的测定;采用H.E染色法对海马神经结构变化情况进行病理学解析。结果血铅和海马铅水平,实验组明显高于对照组 ...
高喆, 刘慧佳, 刘忠民, 陈桂秋
doaj
Studies on the antidepressant-like effect and prokinetic-like effects and the underlying mechanisms of Fructus aurantii and meranzin hydrate [PDF]
, 2016 目的：测定代表中药枳壳汤剂抗抑郁促动力(A&P)的吸收成分，初步阐明其A&P特别是抗抑郁的作用机理。 方法：1.含量测定。运用HPLC/MS/MS测定枳壳汤剂在空肠，海马和前额叶皮层吸收成分；2.急性抗抑郁疗效测试。该实验包括枳壳汤剂及其吸收成分水合橙皮内酯的急性抗抑郁疗效测试。该测试包括强迫游泳实验、旷场实验、习得性无助实验和新奇抑制实验；3.水合橙皮内酯的慢性抗抑郁疗效测试。包括强迫游泳实验和旷场实验；4.离体和在体胃肠动力实验；5.抗抑郁机制研究和抗抑郁促动力的共性机制研究 ...
柳进
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Conservation Biology, Volume 39, Issue 3, June 2025.Abstract Successful long‐term conservation relies on strategic planning for pragmatic actions to mitigate threats. Prioritizing actions and areas to support conservation goals in the most cost‐effective scenario becomes crucial in resource‐limited environments. However, planning and management can be challenging in data‐limited contexts.
Anna Karolina Martins Borges +3 more
wiley +1 more source
China's Eco‐Civilisation, Climate Leviathan, and Hobbesian Energy Transition
Antipode, Volume 57, Issue 3, Page 830-861, May 2025.Abstract Scholars have hitherto tended to theorise China's ecological civilisation project either as a form of environmental authoritarianism or as a vision of eco‐socialism. This paper contributes to the conversation by conducting a textual analysis of Chinese scholarly discussions on eco‐civilisation.
David Chen
wiley +1 more source
The Role of BIN1 in Alzheimer’s Disease [PDF]
, 2015 阿尔茨海默症（Alzheimer’sdisease,AD）是与年龄相关的神经退行性疾病，其主要的病理学特征为由β-淀粉样蛋白(-amyloid,Aβ)聚集产生的老年斑（senileplaues,SP）以及由异常磷酸化的tau蛋白组成的神经纤维缠结（neurofibrillarytangles,NFTs）。Aβ是由淀粉样前体蛋白（-amyloidprecursorprotein,APP）经过β-分泌酶和γ-分泌酶的依次顺序剪切而产生 ...
牛萌萌
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Uncovering Xi Jinping's Policy Agenda: Text As Data Approach
The Developing Economies, Volume 63, Issue 1, Page 9-46, March 2025.How many agendas has Xi Jinping put forth and promoted since taking office in 2012, and what are the types of agendas? How much of political attention has each agenda received, and how has the allocation of attention changed over time? We utilize a dataset of presidential statements, speeches, and reports from 2012 to 2022 and employed automated text ...
Jaehwan Lim, Asei Ito, Hongyong Zhang
wiley +1 more source
The neuronal cell cycle regulation mechanism and related animal model in Alzheimer’s disease [PDF]
, 2015 阿尔茨海默病（Alzheimer’sDisease，AD）是一种与年龄相关的神经退行性疾病，它的主要临床表现是记忆和认知功能的逐渐衰退。AD是一种严重影响人类健康的神经退行性疾病，至今仍未找到有效的治疗方法。因此从预防和早期治疗角度考虑，对于AD早期病理变化的研究就十分重要。成熟神经元处于细胞周期静止期，而在AD中，大量神经元的细胞周期被重新激活，但这些神经元不会再分裂而是最终走向了凋亡，这是目前在AD小鼠模型中已知最早的细胞功能紊乱。但对细胞周期重新激活导致神经元凋亡的机制目前还不清楚 ...
李小萍
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A practical approach to meeting national obligations for sustainable trade under CITES
Conservation Biology, Volume 38, Issue 5, October 2024.Abstract Reconciling conservation goals with sustainable resource use requires adaptive management strategies. The Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) regulates global trade for species listed on Appendix II, partly by requiring member countries (parties) to ensure exports do not damage wild ...
Tanvi Vaidyanathan +3 more
wiley +1 more source