Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Minimally Destructive Radiocarbon Dating of Bone. [PDF]
Higham T +19 more
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Chinese Singaporean Children's Expectations About Peer Group Norms in the Context of Wealth and Ethnicity. [PDF]
Paquette A +3 more
europepmc +1 more source
Longitudinal Relations Among Theory of Mind, Advanced Theory of Mind, and Executive Function From Ages Four to Seven. [PDF]
Osterhaus C +3 more
europepmc +1 more source
Exploring how men's physical activity behaviour changes during and after the Australian Fans-In-Training (Aussie-FIT) program: A qualitative study using the theoretical domains framework. [PDF]
Smith BJ +8 more
europepmc +1 more source
Family protective service involvement and reduced infant cortical grey matter volume. [PDF]
Penner F +4 more
europepmc +1 more source
The Development of Temporal Memory for Complex Events. [PDF]
Frisoni M +4 more
europepmc +1 more source
Automated Near Real-Time QC for LC-HRMS. [PDF]
Mohr MJ +6 more
europepmc +1 more source
Women, Conflict and Public Authority in the Congo [PDF]
Bashwira, Marie-Rose, Cuvelier, Jeroen
core +1 more source

