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Benzylated 1,2,3-triazoles as anticoccidiostats

Journal of Medicinal Chemistry, 1991
Substituted 5-amino-4-carbamoyl-1,2,3-triazoles 3a-w were prepared by two synthetic schemes and evaluated in vivo for anticoccidial activity. Both schemes proceeded by brominating appropriately substituted toluenes 4a-s,v to 5a-s,v. In Scheme I, the brominated benzyl analogues 5 were converted to the corresponding benzyl azides 6, which were treated ...
R J, Bochis   +9 more
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1,2,3-Triazoles: Gas Phase Properties

The Journal of Organic Chemistry, 2013
1,2,3-Triazoles have come to the forefront as compounds of import in a vast number of applications. The fundamental properties of these species, however, remain largely unknown. Herein, the gas phase properties of 4-phenyl-1,2,3-triazole, benzotriazole, and a series of 1-phenylbenzotriazoles are described.
Kai, Wang   +4 more
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Mesoionic 1,2,3-Triazoles and 1,2,3-Triazole Carbenes

2014
Routine access to 1,2,3-triazoles through the copper-catalyzed azide-alkyne “click” cycloaddition reaction has promoted the rapid development of 1,2,3-triazolylidenes as ligands for transition metals. The organometallic complexes containing this kind of N-heterocyclic carbene ligands (NHCs) have shown to possess unique structural characteristics ...
Jesus M. Aizpurua   +2 more
openaire   +1 more source

1,2,3‐Triazoles

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

1,2,3-Triazoles

1974
Publisher Summary This chapter focuses on the chemistry of monocyclic1,2,3-triazoles as much of the chemistry of benzotriazoles and other fused systems has little in common with monocyclic triazole chemistry and provides a broad survey of methods of synthesis and reactions of triazoles. There has been considerable interest in 1,2,3-triazoles as light
T.L. Gilchrist, G.E. Gymer
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1,2,3-Triazoles. Part II. 4-Amino-5-aminomethyl-1,2,3-triazoles

Journal of the Chemical Society, Perkin Transactions 1, 1973
4-Amino-1-(and 2-)methyl-1,2,3-triazole-5-carbonitrile were made by acidic hydrolysis of 4-dimethylaminomethyleneamino-1-(and 2-)methyl-1,2,3-triazole-5-carbonitrile. These amino-nitriles, and also their known 3-methyl- and 3-benzyl-analogues, were hydrogenated to 4-amino-5-aminomethyl-1-methyl-1,2,3-triazole (1a) and its 2- and 3-methyl- and 3-benzyl ...
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Azolyl-substituted 1,2,3-triazoles

Russian Journal of Organic Chemistry, 2016
Huisgen reaction of (E)-1,5-diarylpent-2-en-4-yn-1-ones and (E)-1,5-diarylpent-1-en-4-yn-3-ones afforded 1-aryl-3-(5-aryl-1H-1,2,3-triazol-4-yl)prop-2-en-1-ones and 3-aryl-1-(5-aryl-1H-1,2,3-triazol-4-yl)-prop-2-en-1-ones, respectively. (E)-1-Aryl-3-(5-phenyl-1H-1,2,3-triazol-4-yl)prop-2-en-1-ones reacted with hydrazine hydrate and phenylhydrazine to ...
A. A. Golovanov   +7 more
openaire   +1 more source

Fluorinated 1,2,3‐Triazoles: Terra Incognita in 1,2,3‐Triazoles Chemistry

ChemistrySelect
Abstract This review is devoted to the synthesis and application of fluoro‐substituted 1,2,3‐triazoles. The analysis of the available studies of fluorinated triazoles indicates exceptional value properties especially for biomedical research, despite the significant limitations of synthetic methods of their preparation.
Nazariy Pokhodylo   +2 more
openaire   +1 more source

Aryl trifluoromethyl-1,2,3-triazoles

Journal of Fluorine Chemistry, 1991
Abstract Diaryl-substituted trifluoromethyl-1,2,3-triazoles have been synthesized from aromaticazides and various substituted 1-aryl-3,3,3-trifluoro-1-propynes. The spectroscopic characteristicsof the products and the regioselectivity of the reaction are discussed. Animproved method for the synthesis of 1-aryl-3,3,3-trifluoro-1-propynes from 1-aryl-2-
G. Meazza, G. Zanardi
openaire   +1 more source

Condensed 1,2,3-triazoles (review)

Chemistry of Heterocyclic Compounds, 2008
Methods for the synthesis of condensed 1,2,3-triazoles, including mesoionic compounds, in the literature up to 2007 inclusively are presented. They are classified according to the method by which the molecular skeleton is formed. Mesoionic condensed compounds of the 1,2,3-triazole series are examined separately.
E. A. Shafran   +3 more
openaire   +1 more source

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