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Fluorinated 1,2,3‐Triazoles: Terra Incognita in 1,2,3‐Triazoles Chemistry

ChemistrySelect
Abstract This review is devoted to the synthesis and application of fluoro‐substituted 1,2,3‐triazoles. The analysis of the available studies of fluorinated triazoles indicates exceptional value properties especially for biomedical research, despite the significant limitations of synthetic methods of their preparation.
Nazariy Pokhodylo   +2 more
openaire   +1 more source

Aryl trifluoromethyl-1,2,3-triazoles

Journal of Fluorine Chemistry, 1991
Abstract Diaryl-substituted trifluoromethyl-1,2,3-triazoles have been synthesized from aromaticazides and various substituted 1-aryl-3,3,3-trifluoro-1-propynes. The spectroscopic characteristicsof the products and the regioselectivity of the reaction are discussed. Animproved method for the synthesis of 1-aryl-3,3,3-trifluoro-1-propynes from 1-aryl-2-
G. Meazza, G. Zanardi
openaire   +1 more source

Condensed 1,2,3-triazoles (review)

Chemistry of Heterocyclic Compounds, 2008
Methods for the synthesis of condensed 1,2,3-triazoles, including mesoionic compounds, in the literature up to 2007 inclusively are presented. They are classified according to the method by which the molecular skeleton is formed. Mesoionic condensed compounds of the 1,2,3-triazole series are examined separately.
E. A. Shafran   +3 more
openaire   +1 more source

ChemInform Abstract: 1,2,3‐TRIAZOLES

Chemischer Informationsdienst, 1974
AbstractIn einer Zusammenfassung wird die Synthese der verschiedenen 1,2,3‐Triazole aus Aziden mit Acetylenen oder aktivierten Methylenverbindungen und ausgehend von α‐Diketonen oder α‐Diketonderivaten er1äutert,und die Struktur, die physikalischen Eigenschaften sowie die chemischen Reaktionsweisen der Triazole bei Substitutionsreaktionen, Umwandlung ...
T. L. GILCHRIST, G. E. GYMER
openaire   +1 more source

Synthesis of glucosylated 1,2,3-triazole derivatives

Carbohydrate Research, 1999
A series of potential bioactive compounds, 1-glucosyl-4-heterocyclyl-5-(p-substituted-phenyl)-1,2,3-triazoles , were synthesized. Highly stereoselective products were obtained in good yield. Primary activity screening showed that this type of N-glucosylic compound possessed antitumour and antiviral activities.
X M, Chen, Z J, Li, Z X, Ren, Z T, Huang
openaire   +2 more sources

Organocatalytic routes toward substituted 1,2,3-triazoles

Chemical Communications, 2015
The present feature article describes the different organocatalytic routes for the synthesis of substituted 1,2,3-triazoles.
Jubi, John, Joice, Thomas, Wim, Dehaen
openaire   +2 more sources

Synthesis of substituted septanosyl-1,2,3-triazoles

Carbohydrate Research, 2007
A carbohydrate-based oxepine, derived from 2-deoxy-D-arabino-hexopyranose, was used to prepare a family of septanosyl-1,2,3-triazoles in four steps. DMDO mediated epoxidation of the oxepine followed by trapping of the intermediate 1,2-anhydroseptanose by sodium azide gave the beta-substituted glycosyl azide. The septanosyl azide was then reacted with a
Steve, Castro   +3 more
openaire   +2 more sources

Glycidyl 4‐Functionalized‐1,2,3‐Triazole Polymers

Macromolecular Chemistry and Physics, 2012
AbstractA series of novel polymers, glycidyl 4‐functionalized 1,2,3‐triazole polymers (functionalized GTP) were synthesized by click functionalization of glycidyl azide polymer (GAP). Quantitative functionalization of the glycidyl polymer side groups was achieved due to the high reactivity of the azide–alkyne Huisgen cycloaddition under mild conditions.
Liu, D.   +5 more
openaire   +2 more sources

Structural basis of the impact sensitivities of 1-picryl-1,2,3-triazole, 2-picryl-1,2,3-triazole, 4-nitro-1-picryl-1,2,3-triazole, and 4-nitro-2-picryl-1,2,3-triazole

The Journal of Physical Chemistry, 1989
The isomeric pairs 1-picryl-1,2,3-triazole, 2-picryl-1,2,3-triazole and 4-nitro-1-picryl-1,2,3-triazole, 4-nitro-1-picryl-1,2,3-triazole differ dramatically in their impact sensitivity. Since these pairs of compounds have identical oxygen balance this strongly suggests that there is a difference in the decomposition mechanism.
C. B. Storm   +4 more
openaire   +1 more source

From 1-Sulfonyl-4-aryl-1,2,3-triazoles to 1-Allenyl-5-aryl-1,2,3-triazoles

The Journal of Organic Chemistry, 2017
An efficient and highly regioselective synthesis of 1-allenyl-5-aryl-1,2,3-triazoles from 1-sulfonyl-4-aryl-1,2,3-triazoles is disclosed. 1-Sulfonyl-4-aryl-1,2,3-triazoles reacted with propargylic alcohols in the presence of trifluoroboron etherate to furnish 1-allenyl-5-aryl-1,2,3-triazoles.
Kai Huang   +3 more
openaire   +2 more sources

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