Results 201 to 210 of about 20,375 (237)

1,2,3‐Triazoles in Peptidomimetic Chemistry

European Journal of Organic Chemistry, 2011
AbstractThe ability to synthesise small peptidomimetics that mimic the secondary structure of proteins is an ever expanding area of research directed at sourcing new medicinal agents and biological probes. A significant current challenge is to mimic protein epitopes under physiological conditions using small peptidomimetics that are easy to prepare ...
Pedersen, D., Abell, A.
openaire   +2 more sources

Azolyl-substituted 1,2,3-triazoles

Russian Journal of Organic Chemistry, 2016
Huisgen reaction of (E)-1,5-diarylpent-2-en-4-yn-1-ones and (E)-1,5-diarylpent-1-en-4-yn-3-ones afforded 1-aryl-3-(5-aryl-1H-1,2,3-triazol-4-yl)prop-2-en-1-ones and 3-aryl-1-(5-aryl-1H-1,2,3-triazol-4-yl)-prop-2-en-1-ones, respectively. (E)-1-Aryl-3-(5-phenyl-1H-1,2,3-triazol-4-yl)prop-2-en-1-ones reacted with hydrazine hydrate and phenylhydrazine to ...
A. A. Golovanov, I. S. Odin, V. V. Bekin, A. V. Vologzhanina, I. S. Bushmarinov, S. S. Zlotskii, Yu. L. Gerasimov, P. P. Purygin   +7 more
openaire   +1 more source

ChemInform Abstract: 1,2,3‐TRIAZOLES

Chemischer Informationsdienst, 1974
AbstractIn einer Zusammenfassung wird die Synthese der verschiedenen 1,2,3‐Triazole aus Aziden mit Acetylenen oder aktivierten Methylenverbindungen und ausgehend von α‐Diketonen oder α‐Diketonderivaten er1äutert,und die Struktur, die physikalischen Eigenschaften sowie die chemischen Reaktionsweisen der Triazole bei Substitutionsreaktionen, Umwandlung ...
T. L. GILCHRIST, G. E. GYMER
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1,2,3-Triazoles

2022
Nuno M.M. Moura, Augusto C. Tomé
openaire   +1 more source

Synthesis of 2H-1,2,3-Triazoles

2014
This chapter gives an overview of methods for the synthesis of NH- and N(2)-substituted 1,2,3-triazoles, their advantages, lacks, scope, and limitations. Moreover, it will give some insights on the reaction mechanisms and will explain how different conditions and structure substrates can influence the direction for reactions.
Nataliya Belskaya, Julia Subbotina, Svetlana Lesogorova   +2 more
openaire   +1 more source

Pharmacological Significance of 1,2,3-Triazoles

Click chemistry is not a single specific reaction, but was meant to mimic nature, which also generates substances by joining small modular units. The 1,3-dipolar azide, alkyne cycloaddition (CuAAC) reaction catalyzed by copper, as nearly quantitative and easy to execute has emerged as the leading example of “click chemistry”.
Mubarak Hanif Shaikh, Amol A. Nagargoje, Dattatraya N. Pansare, Bapurao B. Shingate   +3 more
openaire   +1 more source

1,2,3-Triazoles

1996
Wei-Qiang Fan, Alan R. Katritzky
openaire   +1 more source

Catalysis by 1,2,3-triazole- and related transition-metal complexes

Coordination Chemistry Reviews, 2014
Pengxiang Zhao, Didier ASTRUC
exaly  

Cobalt(II) complexes of pyridazine or triazole containing ligands: spin-state control

Coordination Chemistry Reviews, 2003
Sally Brooker
exaly  

Pharmacological significance of triazole scaffold

Journal of Enzyme Inhibition and Medicinal Chemistry, 2011
Rajeev Kharb, M Shahar Yar
exaly