Results 201 to 210 of about 19,900 (217)
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European Journal of Medicinal Chemistry, 2008
The chemical structures of many synthetic activators of large-conductance calcium-activated potassium channels (BK channels) satisfy a simple pharmacophore model, consisting of two appropriately substituted phenyl rings connected by a linker of a heterogeneous nature.
CALDERONE, VINCENZO +6 more
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The chemical structures of many synthetic activators of large-conductance calcium-activated potassium channels (BK channels) satisfy a simple pharmacophore model, consisting of two appropriately substituted phenyl rings connected by a linker of a heterogeneous nature.
CALDERONE, VINCENZO +6 more
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Journal of Fluorine Chemistry, 2016
Abstract The titration of a series of fluorous bis(1,2,3-triazol-4-ylmethyl) molecules with camphorsulfonic acid has been examined by 1 H NMR spectroscopy to investigate any conformational changes that might occur on protonation; it is envisaged that this information will assist in predicting their potential as ligands.
Dominic V. Francis +2 more
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Abstract The titration of a series of fluorous bis(1,2,3-triazol-4-ylmethyl) molecules with camphorsulfonic acid has been examined by 1 H NMR spectroscopy to investigate any conformational changes that might occur on protonation; it is envisaged that this information will assist in predicting their potential as ligands.
Dominic V. Francis +2 more
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ChemInform Abstract: 1,2,3‐TRIAZOLES PART 2, 4‐AMINO‐5‐AMINOMETHYL‐1,2,3‐TRIAZOLES
Chemischer Informationsdienst, 1973AbstractDurch Hydrolyse des Azomethins (I) wird das Aminocarbonitril (II) dargestellt; das Isomere (III) wird analog gewonnen.
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Journal of the Chemical Society C: Organic, 1968
A number of 1-aryl 1,2,3-triazoles have been synthesised; their u.v. absorption data and the apparent dissociation constants of the derived carboxylic acids are given. 1-Aryl 1,2,3-triazoles are nitrated and brominated in the 4-position of the phenyl ring.
H. El Khadem +2 more
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A number of 1-aryl 1,2,3-triazoles have been synthesised; their u.v. absorption data and the apparent dissociation constants of the derived carboxylic acids are given. 1-Aryl 1,2,3-triazoles are nitrated and brominated in the 4-position of the phenyl ring.
H. El Khadem +2 more
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Organic Preparations and Procedures, 1970
T. E. Eagles, M. A. Khan, B. M. Lynch
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T. E. Eagles, M. A. Khan, B. M. Lynch
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13.13.6 1,2,3-Triazoles (Update 2015)
2016AbstractThis chapter is an update to the earlier Science of Synthesis contribution (Section 13.13) describing methods for the synthesis of 1,2,3-triazoles. Recent interest in this area has mainly been generated by the discovery that copper(I)-catalyzed azide–alkyne cycloaddition (CuAAC) and ruthenium(II)-catalyzed azide–alkyne cycloaddition (RuAAC ...
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