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Synthesis and Characterization of Azido-Functionalized 1,2,3-Triazole and Fused 1,2,3-Triazole

The Journal of Organic Chemistry, 2023
Here, we report the nitration of NH on the 1,2,3-triazole ring and the synthesis of several nitrogen-rich energetic compounds based on key intermediate 4-azido-5-(chlorodinitromethyl)-2-nitro-2H-1,2,3-triazole (5). Starting from 4-amino-1H-1,2,3-triazole-5-carbonitrile (1), we successfully constructed compound 5 through four steps.
Yupeng Cao   +4 more
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Synthesis of 1,2,3‐Triazoles.

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Dolly Dolly   +2 more
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Benzylated 1,2,3-triazoles as anticoccidiostats

Journal of Medicinal Chemistry, 1991
Substituted 5-amino-4-carbamoyl-1,2,3-triazoles 3a-w were prepared by two synthetic schemes and evaluated in vivo for anticoccidial activity. Both schemes proceeded by brominating appropriately substituted toluenes 4a-s,v to 5a-s,v. In Scheme I, the brominated benzyl analogues 5 were converted to the corresponding benzyl azides 6, which were treated ...
R J, Bochis   +9 more
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Mesoionic 1,2,3-Triazoles and 1,2,3-Triazole Carbenes

2014
Routine access to 1,2,3-triazoles through the copper-catalyzed azide-alkyne “click” cycloaddition reaction has promoted the rapid development of 1,2,3-triazolylidenes as ligands for transition metals. The organometallic complexes containing this kind of N-heterocyclic carbene ligands (NHCs) have shown to possess unique structural characteristics ...
Jesus M. Aizpurua   +2 more
openaire   +1 more source

1,2,3-Triazoles

1974
Publisher Summary This chapter focuses on the chemistry of monocyclic1,2,3-triazoles as much of the chemistry of benzotriazoles and other fused systems has little in common with monocyclic triazole chemistry and provides a broad survey of methods of synthesis and reactions of triazoles. There has been considerable interest in 1,2,3-triazoles as light
T.L. Gilchrist, G.E. Gymer
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1,2,3‐Triazoles

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Synthesis of 1,2,3‐Triazole Analogues of Lincomycin

Helvetica Chimica Acta, 2008
AbstractIn search for new antibiotics we replaced the amide moiety of lincomycin 1 by a 1,2,3‐triazole ring. The 1,2,3‐triazoles 10a–10k were obtained as single regioisomers by ‘click reaction’ of azide 5 with the alkyne 9k, derived from propyl hygric acid, and the alkyl, aryl, or cycloalkyl alkynes ribosomes 9a–9j.
Collin, M P   +3 more
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1,2,3-Triazoles: Gas Phase Properties

The Journal of Organic Chemistry, 2013
1,2,3-Triazoles have come to the forefront as compounds of import in a vast number of applications. The fundamental properties of these species, however, remain largely unknown. Herein, the gas phase properties of 4-phenyl-1,2,3-triazole, benzotriazole, and a series of 1-phenylbenzotriazoles are described.
Kai, Wang   +4 more
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Synthesis of substituted septanosyl-1,2,3-triazoles

Carbohydrate Research, 2007
A carbohydrate-based oxepine, derived from 2-deoxy-D-arabino-hexopyranose, was used to prepare a family of septanosyl-1,2,3-triazoles in four steps. DMDO mediated epoxidation of the oxepine followed by trapping of the intermediate 1,2-anhydroseptanose by sodium azide gave the beta-substituted glycosyl azide. The septanosyl azide was then reacted with a
Steve, Castro   +3 more
openaire   +2 more sources

Fluorinated 1,2,3‐Triazoles: Terra Incognita in 1,2,3‐Triazoles Chemistry

ChemistrySelect
Abstract This review is devoted to the synthesis and application of fluoro‐substituted 1,2,3‐triazoles. The analysis of the available studies of fluorinated triazoles indicates exceptional value properties especially for biomedical research, despite the significant limitations of synthetic methods of their preparation.
Nazariy Pokhodylo   +2 more
openaire   +1 more source

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