Results 91 to 100 of about 43,142 (242)
, 2016 A copper(I)-catalyzed tandem CuAAC/alkynylation reaction of various alkynes, organic azides, and bromoalkynes to provide rapid access to 5-alkynyl-1,2,3-triazoles has been developed.
Chen-Ho Tung (654283) +4 more
core +1 more source
, 2020 A copper-catalyzed decarboxylative cycloaddition of propiolic acids, azides, and arylboronic acids is described. The present reaction provides an efficient and convenient method for the synthesis of various fully substituted 1,2,3-triazoles from readily ...
Ya-Min Li +13 more
core +1 more source
Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles
European Journal of Organic Chemistry, EarlyView.Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu +2 more
wiley +1 more source
Selective N‐Functionalization of Pyrazoles
European Journal of Organic Chemistry, EarlyView.This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek +2 more
wiley +1 more source
, 2016 A multicomponent multicatalyst reaction (MC)2R for constructing fully substituted 1,2,3-triazoles is reported. An application of chemoselectivity and latent catalysis in a sequence of multicatalytic reactions confers control over a number of undesired ...
Mark Lautens (1391935) +4 more
core +1 more source
Photocatalysis‐Triggered Click Reactions and Applications
European Journal of Organic Chemistry, EarlyView.Photoclick chemistry offers broad applications ranging from materials science to bioconjugation, with precise spatiotemporal control over click reactions. Initially limited to UV activation, recent advances have extended photoclick processes to the visible and NIR regions thanks to the photocatalysis.
Margaux Walter +2 more
wiley +1 more source
Síntese e caracterização de cristais líquidos contendo o heterociclo 1,2,3-triazol 1,4-dissubstituído [PDF]
, 2006 TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.A síntese de compostos que possuem anéis do tipo 1,2,3 triazol têm atraído a atenção de vários estudiosos.
BRYK, Fernando Rebouças
core
, 2019 In search of more potent new antitubercular agents, a library of novel piperazine tethered dimeric 1,2,3-triazoles were designed by assembling 1,2,3-triazoles and piperazine in a single molecular architectural framework.
Jaiprakash N. Sangshetti (4842510) +6 more
core +1 more source
Journal of Heterocyclic Chemistry, EarlyView.One‐pot gold(I)‐catalysts synthesis was developed in order to prepare N‐alkenyl 2‐pyridonyl azides. This method provides a series of N‐alkenyl 2‐pyridonyl azides in moderate to excellent yields (up to 94%). ABSTRACT A novel strategy, involving the preparation of gold‐catalyzed cyclization salts and the rearrangement of these salts in the presence of ...
Ali Osman Karatavuk
wiley +1 more source
Triazoles as promising small molecules anticancer agents [PDF]
Records of Pharmaceutical & Biomedical SciencesThe 1,2,3-triazole scaffold has emerged as a pivotal heterocyclic motif in medicinal chemistry due to its unique physicochemical properties, synthetic accessibility, and broad spectrum of biological activities. These five-membered nitrogen-rich rings are
Mennatallah Shaheen +4 more
doaj +1 more source