Results 71 to 80 of about 12,017 (229)
The synthesis of 1,2,3-triazoles with immobilized Cu(I) in thiosemicarbazide-functionalized β-cyclodextrin (Cu@TSC-β‐CD) as a supramolecular catalyst was discussed.
Mahdieh Tajbakhsh +1 more
doaj +1 more source
A administração de antimicrobianos nos casos de doenças infecciosas é inevitável, porém seu uso excessivo e indiscriminado vem influenciando na resistência bacteriana. Este cenário de saúde constitui uma extensa ameaça à população enferma e necessitada de tratamento terapêutico, o que torna necessário o empenho da comunidade científica na pesquisa e ...
Guilheane Gonçalves Barbosa +1 more
openaire +1 more source
Engineering Bisubstrates to Target m6Am RNA Methyltransferases: Synthesis and Computational Studies
Use of the convertible nucleoside approach to synthesize m6Am RNA methyltransferase bisubstrates. This methodology allows for the introduction of modifications on the SAM analog moiety and the RNA substrate part, including the introduction of a cap analog by click chemistry.
Yoann Colas +3 more
wiley +1 more source
One-Pot Synthesis of Tetrazole–Triazole Bis-Heterocycles via Ugi–Azide Reaction
Bioisosteres of amide bonds such as 4,5-disubstituted-1,2,3-triazoles (4,5-DS-1,2,3-Ts) and 1,5-disubstituted tetrazoles (1,5-DST) are present in compounds with important biological activities like those that are antineoplastic, antibacterial, antifungal,
Fidel Rodriguez-Lopez +3 more
doaj +1 more source
Recent advances in the synthesis of triazole derivatives [PDF]
Triazole ring system has attracted a continuously growing interest of synthetic organic chemists and those dealing with the medicinal compounds due to its versatile potential to interact with biological systems.
Ahmad, Matloob +6 more
core
Ir pincer complexes bearing a triazole architecture in the pincer backbone and O‐ancillary chelating ligands are presented. These were employed in the catalytic transfer dehydrogenation of alkanes as well as of saturated heterocycles. Reactivity of these complexes with silver salts and Lewis acids produced various cationic iridium complexes.
Jesvita Cardozo +5 more
wiley +1 more source
The 1,2-naphthoquinone compound was previously considered active against solid tumors. Moreover, glycosidase inhibitors such as 1,2,3-1H triazoles has been pointed out as efficient compounds in anticancer activity studies.
INGRID C. CHIPOLINE +5 more
doaj +1 more source
Copper(II)-benzotriazole coordination compounds in click chemistry: a diagnostic reactivity study [PDF]
This diagnostic study aims to shed light on the catalytic activity of a library of Cu(II) based coordination compounds with benzotriazole-based ligands.
Abdul-Sada, Alaa +8 more
core +1 more source
A Low‐Symmetry FeII Tetrahedron From a Flexible Tritopic Ligand
A highly symmetric and flexible tris‐bidentate tritopic ligand forms an S4 meso homoleptic face‐capped FeII tetrahedron near‐quantitatively in acetonitrile. The addition of nitromethane solvent causes partial isomerization of this meso cage to the racemic homochiral tetrahedron, with the complexity of the system being moderated through solvophobic ...
Rosemary J. Goodwin +5 more
wiley +1 more source
International audienceDFT calculations at the PBE0/LANL2DZ level have been performed on model compounds to investigate the reaction mechanism of two recently reported metal-catalyzed alkyne azide cycloaddition (MAAC).
Astruc, Didier +5 more
core +3 more sources

