Results 41 to 50 of about 94,532 (279)

Morpholine-mediated defluorinative cycloaddition of gem-difluoroalkenes and organic azides

Beilstein Journal of Organic Chemistry, 2023
Here, we report the first transition-metal-free defluorinative cycloaddition of gem-difluoroalkenes with organic azides in morpholine as a solvent to construct fully decorated morpholine-substituted 1,2,3-triazoles.
Tzu-Yu Huang, Mario Djugovski, Sweta Adhikari, Destinee L. Manning, Sudeshna Roy   +4 more
doaj   +1 more source

Preparation of Quinoline-2,4-dione Functionalized 1,2,3-Triazol-4-ylmethanols, 1,2,3-Triazole-4-carbaldehydes and 1,2,3-Triazole-4-carboxylic Acids

Acta Chimica Slovenica, 2020
(1-(2,4-Dioxo-1,2,3,4-tetrahydroquinolin-3-yl)-1H-1,2,3-triazol-4-yl)methyl acetates substituted on nitrogen atom of quinolinedione moiety with propargyl group or (1-substituted 1H-1,2,3-triazol-4-yl)methyl group, which are available from the appropriate 3-(4-hydroxymethyl-1H-1,2,3-triazol-1-yl)quinoline-2,4(1H,3H)-diones unsubstituted on quinolone ...
Milićević, David, Kimmel, Roman, Urankar, Damijana, Pevec, Andrej, Kosmrlj, Janez, Kafka, Stanislav   +5 more
openaire   +4 more sources

Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition [PDF]

, 2011
A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the ...
Engels, Joachim W., Krim, Jamal, Taourirte, Mohamed   +2 more
core   +2 more sources

Phosphonylated Acyclic Guanosine Analogues with the 1,2,3-Triazole Linker [PDF]

Molecules, 2015
A novel series of {4-[(2-amino-6-chloro-9H-purin-9-yl)methyl]-1H-1,2,3-triazol-1-yl}alkylphosphonates and {4-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methyl]-1H-1,2,3-triazol-1-yl}alkylphosphonates as acyclic analogues of guanosine were synthesized and assessed for antiviral activity against a broad range of DNA and RNA viruses and for their ...
Głowacka, Iwona E., Andrei, Graciela, Schols, Dominique, Snoeck, Robert, Piotrowska, Dorota G.   +4 more
openaire   +6 more sources

Copper Nanoparticles in Click Chemistry [PDF]

, 2015
Conspectus: The challenges of the 21st century demand scientific and technological achievements that must be developed under sustainable and environmentally benign practices.
Alonso, Francisco, Moglie, Yanina, Radivoy, Gabriel   +2 more
core   +2 more sources

1,2,3-Triazoles

, 2008
Rapid progress in the synthetic application of benzotriazole derivatives in the last 20 years has resulted in over 1000 scientific papers on the subject. This fact is reflected in Section 5.01.7, which involves almost a half of the volume of this chapter. The section is arranged according to hybridization of the C-α atom and atomic numbers of the atoms
Rachwal, S., Katritzky, A.R.
openaire   +1 more source

Fullerenyl-1,2,3-Triazoles: Synthesis and Cytotoxic Activity

The 25th International Electronic Conference on Synthetic Organic Chemistry, 2021
Through the reaction of fullerenylazide with terminal acetylenes, previously undescribed 1-butyl-2-triazolylfullerenes, in which the heterocyclic fragment was directly attached to the fullerene backbone, were synthesized for the first time. Water-soluble complexes of the synthesized adducts of fullerene with polyvinylpyrrolidone showed a high cytotoxic
Zarema R. Sadretdinova, Arslan R. Akhmetov, Lilya U. Dzhemileva, Vladimir A. D’yakonov, Airat Tuktarov, Usein Dzhemilev   +5 more
openaire   +2 more sources

The gas phase cyclization of deprotonated N-aryl-2-cyano-2-diazoacetamides [PDF]

, 2005
The document attached has been archived with permission from the publisher.1-Aryl-4-cyano-5-hydroxy-1,2,3-triazoles can be obtained in solution by base-catalysed cyclization of N-aryl-2-cyano-2-diazoacetamides.
Bilusich, D., Blumenthal, T., Bowie, J., Lebedev, A., Lobodin, V., Morzherin, Y., Ovcharenko, V.   +6 more
core   +2 more sources

Coordinatively unsaturated ruthenium complexes as efficient alkyne-azide cycloaddition catalysts [PDF]

, 2012
The performance of 16-electron ruthenium complexes with the general formula Cp*Ru(L)X (in which L = phosphine or N-heterocyclic carbene ligand; X = Cl or OCH2CF3) was explored in azide−alkyne cycloaddition reactions that afford the 1,2,3- triazole ...
Broggi, Julie, Cavallo, Luigi, Fortman, George C., Lamberti, Marina, Nolan, Steven P., Poater, Albert, Slawin, Alexandra M. Z.   +6 more
core   +2 more sources

Microwave assisted metal-free approach to access 1,2,3-triazoles through multicomponent synthesis

Current Research in Green and Sustainable Chemistry, 2020
The work illustrates multicomponent reaction of aldehydes, nitroalkanes and sodium azide for the metal-free synthesis of N-unsubstituted-1,2,3-triazoles using anthranilic acid as an organocatalyst under microwave irradiation. This is the first ever green
Anirban Garg, Diganta Sarma, Abdul Aziz Ali   +2 more
doaj   +1 more source