Results 61 to 70 of about 11,474 (185)

Design and Synthesis of New 5-aryl-4-Arylethynyl-1H-1,2,3-triazoles with Valuable Photophysical and Biological Properties

Molecules, 2021
Cu-catalyzed 1,3-dipolar cycloaddition of methyl 2-azidoacetate to iodobuta-1,3-diynes and subsequent Suzuki-Miyaura cross-coupling were used to synthesize new triazoles derivatives: 5-aryl-4-arylethynyl-1H-1,2,3-triazoles. Investigation of their optical
Mariia M. Efremova, Anastasia I. Govdi, Valeria V. Frolova, Andrey M. Rumyantsev, Irina A. Balova   +4 more
doaj   +1 more source

ZrCl4-catalyzed C-O bond to C-N bond formation: synthesis of 1,2,3-triazoles and their biological evaluation [PDF]

, 2014
A simple and efficient protocol was developed for the synthesis of aryl azides directly from aryl carbinols using ZrCl4as a Lewis acid catalyst. The azides were converted to novel triazoles under click reaction conditions, which were evaluated for their ...
Buddana, S, Hugel, H, Kandikonda, S, Prakasham, R, Reddy, S, Sharma, G   +5 more
core   +1 more source

Synthesis of Carvone-Derived 1,2,3-Triazoles Study of Their Antioxidant Properties and Interaction with Bovine Serum Albumin

Molecules, 2018
Natural L-carvone was utilized as a starting material for an efficient synthesis of some terpenyl-derived 1,2,3-triazoles. Chlorination of carvone, followed by nucleophilic substitution with sodium azide resulted in the preparation of 10-azidocarvone ...
Armen S. Galstyan, Armen I. Martiryan, Karine R. Grigoryan, Armine G. Ghazaryan, Melanya A. Samvelyan, Tariel V. Ghochikyan, Valentine G. Nenajdenko   +6 more
doaj   +1 more source

Synthesis of a Novel Series of Cu(I) Complexes Bearing Alkylated 1,3,5-Triaza-7-phosphaadamantane as Homogeneous and Carbon-Supported Catalysts for the Synthesis of 1- and 2-Substituted-1,2,3-triazoles

Nanomaterials, 2021
The N-alkylation of 1,3,5-triaza-7-phosphaadamantane (PTA) with ortho-, meta- and para-substituted nitrobenzyl bromide under mild conditions afforded three hydrophilic PTA ammonium salts, which were used to obtain a new set of seven water-soluble copper ...
Ivy L. Librando, Abdallah G. Mahmoud, Sónia A. C. Carabineiro, M. Fátima C. Guedes da Silva, Carlos F. G. C. Geraldes, Armando J. L. Pombeiro   +5 more
doaj   +1 more source

Regioselective synthesis, characterization and antimicrobial evaluation of amide-ether linked 1,4-disubstituted 1,2,3-triazoles [PDF]

Journal of the Serbian Chemical Society, 2017
Regioselective synthesis of some amide–ether-linked 1,4-disubstituted 1,2,3-triazoles was realized via the copper(I)-catalyzed click reaction of 1-(prop-2-ynyloxy)naphthalene, 2-(prop-2-ynyloxy)naphthalene and 1,4-bis-(prop-2-ynyloxy)benzene with 2-azido-
Kaushik Chander Prakash, Kumar Krishan, Kumar Devinder, Mor Satbir, Kumar Ashwani, Kumar Jindal Deepak   +5 more
doaj   +1 more source

Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents [PDF]

, 2017
Two series of N-(aryl)-1-(hydroxyalkyl)pyrrolidine-2-carboxamides (2a-2g and 3a-3g) and 1,4-disubstituted 1,2,3-triazoles (5a-5h and 8a-8h) were synthesized.
Bianco, Roberto, Caliendo, Giuseppe, Ciciola, Paola, Cirino, Giuseppe, Corvino, Angela, Fiorino, Ferdinando, Frecentese, Francesco, Incisivo, Giuseppina Maria, Magli, Elisa, Perissutti, Elisa, Riemma, Maria Antonietta, Rosa, Roberta, Roviezzo, Fiorentina, Saccone, Irene, Santagada, Vincenzo, Severino, Beatrice, Temussi, Piero A   +16 more
core   +2 more sources

Design, synthesis, in silico and in vitro antimicrobial screenings of novel 1,2,4-triazoles carrying 1,2,3-triazole scaffold with lipophilic side chain tether

Chemistry Central Journal, 2017
Background 1,2,4-Triazoles and 1,2,3-triazoles have gained significant importance in medicinal chemistry. Results This study describes a green, efficient and quick solvent free click synthesis of new 1,2,3-triazole-4,5-diesters carrying a lipophilic side
Mohamed Reda Aouad, Mariem Mohammed Mayaba, Arshi Naqvi, Sanaa K. Bardaweel, Fawzia Faleh Al-blewi, Mouslim Messali, Nadjet Rezki   +6 more
doaj   +1 more source

Novel allyl-hydrazones including 2,4-dinitrophenyl and 1,2,3-triazole moieties as optical sensor for ammonia and chromium ions in water

BMC Chemistry, 2022
It is critical to take safety action if carcinogenic heavy metals and ammonia can be detected quickly, cheaply, and selectively in an environmental sample. As a result, compound 4a [4-(1-(2-(2,4-Dinitrophenyl)hydrazineylidene)-3-(naphthalen-2-yl)allyl)-5-
Hanan A. Mohamed, Bakr F. Abdel-Wahab, Mahmoud N. M. Yousif, Reda M. Abdelhameed   +3 more
doaj   +1 more source

Regioselective Formation of 2,5-Disubstituted Oxazoles Via Copper(I)-Catalyzed Cycloaddition of Acyl Azides and 1-Alkynes [PDF]

, 2011
The reaction of 1-alkynes with acylazides in the presence of [Tpm*,BrCu(NCMe)]BF4 (Tpm*,Br = tris(3,5-dimethyl-4-bromopyrazolyl)methane) as the catalyst provides 2,5-oxazoles in moderate to high yields.
Cano Rico, Israel, Nicasio Jaramillo, María Carmen, Pérez Romero, Pedro José, Álvarez, Eleuterio   +3 more
core   +1 more source

Strategies Towards the Synthesis of N2-Substituted 1,2,3-Triazoles

Anais da Academia Brasileira de Ciências, 2019
The chemistry of 1,2,3-triazoles gained much attention since the discovery of the copper catalyzed Alkyne-azide cycloaddition (CuAAC) reaction which delivers exclusively the 1,4-regioisomer in high yields.
RODRIGO OCTÁVIO M.A. DE SOUZA, LEANDRO S. DE MARIZ E MIRANDA   +1 more
doaj   +1 more source