HNO made-easy from photochemical cycloreversion of novel 3,5-heterocyclic disubstituted 1,2,4-oxadiazole-4-oxides [PDF]
, 2013 A variety of symmetric and asymmetric 3,5-heterocyclic disubstituted 1,2,4-oxadiazole-4-oxides have been prepared through cycloaddition of aromatic and heteroaromatic nitrile oxides to heteroaromatic amidoximes. A library of novel, fully characterized,
DONDI, DANIELE +4 more
core
Total Synthesis of Anhydrolycorinone Utilizing Sequential Intramolecular Diels−Alder Reactions of a 1,3,4-Oxadiazole [PDF]
, 2016 A convergent total synthesis of anhydrolycorinone is detailed, enlisting sequential intramolecular Diels−Alder reactions of a suitably substituted 2-amino-1,3,4-oxadiazole defining a novel oxadiazole → furan → benzene Diels−Alder ...
Dale L. Boger (1306542) +1 more
core +1 more source
Acta Scientiarum: Technology, 2005 The known oxadiazoles 3,5-bis-(phenyl)-1,2,4-oxadiazole (3a); the 3-(4-chlorophenyl)-5-phenyl-1,2,4-oxadiazole (3b); and the new 3,5-diphenylchlorinated-1,2,4-oxadiazoles 3c-e were synthesized from the reaction of benzamidoximes with an appropriated acid
Silvio Luiz Machado +4 more
doaj
C-13 NMR study of substituent effects in 1,2,4-oxadiazole and 1,2,4-thiadiazole derivatives [PDF]
, 2004 C-13 chemical shifts of C=N, C=O and C=S carbons of 3,4-distibstituted-1,2,4-oxadiazole-5-ones(thiones) and 3,4-disubstituted-1,2,4-thiadiazole-5-ones have been determined ill CDCl3 solution.
Kara, YEŞİM SANİYE, Agirbas, H
core +1 more source
Synthesis and chemical characterization of CuII, NiII and ZnII complexes of 3,5-bis(20-pyridyl)-1,2,4-oxadiazole and 3-(20-pyridyl)5-(phenyl)-1,2,4-oxadiazole ligands [PDF]
, 2011 The synthesis and structural characterization of NiII, CuII and ZnII complexes of two chelating 1,2, 4-oxadiazole ligands, namely 3,5-bis(20-pyridyl)-1,2,4-oxadiazole (bipyOXA) and 3-(20-pyridyl)5- (phenyl)-1,2,4-oxadiazole (pyOXA), is here reported ...
Giorgi, G +13 more
core +1 more source
4-[3-(Phenoxymethyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazin-6-yl]-3-(p-tolyl)sydnone
Acta Crystallographica Section E, 2010 In the title triazolothiadiazine derivative, C20H16N6O3S {systematic name: 3-(4-methylphenyl)-4-[3-(phenoxymethyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazin-6-yl]-1,2,3-oxadiazol-3-ium-5-olate}, an S(6) ring motif is generated by an intramolecular C&#
Jia Hao Goh +3 more
doaj +1 more source
Expanding Synthesizable Space of Disubstituted 1,2,4-Oxadiazoles
ACS Combinatorial Science, 2016 One-pot synthesis of 3,5-disubstituted 1,2,4-oxadiazoles from carboxylic acids and nitriles was optimized to parallel chemistry. The method was validated on a 141 member library; the desired products were recovered with a high success rate and in moderate yields.
Andrey, Tolmachev +10 more
openaire +2 more sources
Focused microwave irradiation-assisted synthesis of N-cyclohexyl-1,2,4-oxadiazole derivatives with antitumor activity [PDF]
, 2019 A facile synthesis of 3,5-disubstituted 1,2,4-oxadiazole derivatives under focused microwave irradiation (FMWI) is reported. Arylamidoximes 1a–i and dicyclohexylcarbodiimide (DCC) were carried out in DMF under FMWI to obtain 1,2,4-oxadiazoles 2a–i in 61 ...
Roberto Nicolete (90567) +6 more
core +1 more source
The preparation and rearrangement of 3- pyridyl-4-alkyl (or aryl)-1,2,4- oxadiazole-5 (4h)-thiones [PDF]
, 1991 3-Pyridyl-4-alkyl (or aryl)-1,2,4-oxadiazole-5(4H)-thiones are prepared by the reaction of N-alkyl (or aryl) pyridine carboxamide oximes with thiophosgene.
Ağırbaş, Hikmet, Dürüst, Yaşar
core +1 more source
(S)-tert-Butyl 3-(3-phenyl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxylate
Acta Crystallographica Section E, 2010 The title compound, C18H23N3O3, crystallized with two independent molecules (A and B) in the asymmetric unit. The phenyl ring and the 1,2,4-oxadiazole ring are inclined to one another by 19.9 (3)° in molecule A and 7.3 (3 ...
Lin Liu +4 more
doaj +1 more source