Results 101 to 110 of about 101,287 (245)

Synthesis, toxicity towards brine shrimp (Artemia salina Leach) and antimicrobial activity evaluation of 3,5-diphenylchlorinated-1,2,4- oxadiazoles = Síntese, toxicidade frente a Artemia salina Leach e avaliação da atividade antimicrobiana de 1,2,4-oxadiazóis-3,5-difenilclorados

open access: yesActa Scientiarum: Technology, 2005
The known oxadiazoles 3,5-bis-(phenyl)-1,2,4-oxadiazole (3a); the 3-(4-chlorophenyl)-5-phenyl-1,2,4-oxadiazole (3b); and the new 3,5-diphenylchlorinated-1,2,4-oxadiazoles 3c-e were synthesized from the reaction of benzamidoximes with an appropriated acid
Silvio Luiz Machado   +4 more
doaj  

4-[3-(Phenoxymethyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazin-6-yl]-3-(p-tolyl)sydnone

open access: yesActa Crystallographica Section E, 2010
In the title triazolothiadiazine derivative, C20H16N6O3S {systematic name: 3-(4-methylphenyl)-4-[3-(phenoxymethyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazin-6-yl]-1,2,3-oxadiazol-3-ium-5-olate}, an S(6) ring motif is generated by an intramolecular C&#
Jia Hao Goh   +3 more
doaj   +1 more source

Expanding Synthesizable Space of Disubstituted 1,2,4-Oxadiazoles

open access: yesACS Combinatorial Science, 2016
One-pot synthesis of 3,5-disubstituted 1,2,4-oxadiazoles from carboxylic acids and nitriles was optimized to parallel chemistry. The method was validated on a 141 member library; the desired products were recovered with a high success rate and in moderate yields.
Andrey, Tolmachev   +10 more
openaire   +2 more sources

(S)-tert-Butyl 3-(3-phenyl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxylate

open access: yesActa Crystallographica Section E, 2010
The title compound, C18H23N3O3, crystallized with two independent molecules (A and B) in the asymmetric unit. The phenyl ring and the 1,2,4-oxadiazole ring are inclined to one another by 19.9 (3)° in molecule A and 7.3 (3 ...
Lin Liu   +4 more
doaj   +1 more source

Estudo computacional de complexos mononucleares de cobre (II) e zinco (II) com ligantes triazólicos [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2013.Neste trabalho foram estudados complexos mononucleares de cobre(II) ou zinco(II ...
Fonseca, David Edson Pedrosa
core  

(3+2) Annulation of amidinothioureas with binucleophile: Synthesis and antimicrobial of 3-phenylamino-5-aryl/alkyl-1,2,4-oxadiazole derivatives

open access: yes, 2014
Herein, we report an efficient method for preparation of 3‐phenylamino‐5‐aryl/alkyl‐1,2,4‐oxadiazole by (3+2) annulation of amidinothioureas with binucleophilic hydroxylamine hydrochloride in the presence of mercury (II) chloride. Desired 3‐phenylamino‐5‐
Wang, Kan   +5 more
core   +1 more source

Synthesis of Some New Heterocyclic Fused Rings Compounds Based on 5-Aryl-1,3,4-Oxadiazole

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
The work includes synthesis and characterization of some new heterocyclic compounds, as flow: The compound (3) (5-(4-chlorophenyl) -2-hydrazinyl-1,3,4-oxadiazole was synthesized by using two methods; the first method includes the direct reaction between
Zahra Mohammed Abbas   +2 more
doaj  

An interesting ring cleavage of a 1,2,4-oxadiazole ring

open access: yes, 2017
Ring-opening reaction: owing to the instability of the 1,2,4-oxadiazole ring under acidic conditions, unexpected compounds 2 and 3 were obtained. Compound 2 exhibits an oxygen balance of zero, density of 1.89 g cm−1 and detonation velocity of 9307 m s−1 ...
Hongwei Yang   +4 more
core   +1 more source

UNUSUAL WAY OF REACTION OF 3-AMINO-4-(5-CHLOROMETHYL-1,2,4-OXADIAZOLE-3-YL)-FURAZAN WITH HYDRAZINE

open access: yes, 2017
The results of our study of the pathways of selective reactivity of 3-amino-4-(5-chloromethyl-1,2,4-oxadiazole-3-yl)furazan versus 5-unsubstituted or 5-methyl and 5-trifluoromethyl substituted 4-(5R-1,2,4-oxadiazole-3-yl)furazans (R = H, Me, CF3) towards
Elena V. Stepanova, Andrei I. Stepanov
core   +1 more source

Molecular docking and molecular dynamics simulation studies of inhibitor candidates against Anopheles gambiae 3-hydroxykynurenine transaminase and implications on vector control

open access: yesHeliyon
Isoxazole and oxadiazole derivatives inhibiting 3-hydroxykynurenine transaminase (3HKT) are potential larvicidal candidates. This study aims to identify more suited potential inhibitors of Anopheles gambiae 3HKT (Ag3HKT) through molecular docking and ...
Eunice O. Adedeji   +6 more
doaj   +1 more source

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