Results 101 to 110 of about 31,516 (214)

Estudo computacional de complexos mononucleares de cobre (II) e zinco (II) com ligantes triazólicos [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2013.Neste trabalho foram estudados complexos mononucleares de cobre(II) ou zinco(II ...
Fonseca, David Edson Pedrosa
core  

Rearrangements of 1,2,4-Oxadiazole: "One Ring to Rule Them All" [PDF]

, 2017
[Figure not available: see fulltext.] 1,2,4-Oxadiazoles are heterocycles characterized by low aromaticity and the presence of a weak OâN bond and are widely studied due to their tendency to rearrange into more stable heterocyclic compounds.
Antonio Palumbo Piccionello, Buscemi, Silvestre, Silvestre Buscemi, Andrea Pace, Piccionello, Antonio Palumbo, Pace, Andrea   +5 more
core   +1 more source

Identification of diaryl 5-amino-1,2,4-oxadiazoles as tubulin inhibitors: The special case of 3-(2-fluorophenyl)-5-(4-methoxyphenyl)amino-1,2,4-oxadiazole [PDF]

, 2013
The combination of experimental (inhibition of colchicine binding) and computational (COMPARE, docking studies) data unequivocally identified diaryl 5-amino-1,2,4-oxadiazoles as potent tubulin inhibitors.
Hamel, Ernest, Nguyen, Tam Luong, A. Gakh, Andrei, V. Sosnov, Andrey, Krasavin, Mikhail   +4 more
core   +1 more source

Design and Synthesis of 1,2,4-Oxadiazole Derivatives as Non-Steroidal 5 Alpha-Reductase Inhibitors [PDF]

, 2009
The purpose of this study was to synthesize compounds in which the 1,2,4- oxadiazole moiety replaced the amide bond of ONO3805 and to evaluate its 5 alpha-reductase inhibitory activity as a potential benign prostatic hyperplasia therapeutic target.
CHERN, JI-WANG, 陳基旺
core  

Synthesis of Some New Heterocyclic Fused Rings Compounds Based on 5-Aryl-1,3,4-Oxadiazole

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
The work includes synthesis and characterization of some new heterocyclic compounds, as flow: The compound (3) (5-(4-chlorophenyl) -2-hydrazinyl-1,3,4-oxadiazole was synthesized by using two methods; the first method includes the direct reaction between
Zahra Mohammed Abbas, Dhuha Faruq Hussain, Raied Mustafa Shakir   +2 more
doaj  

Discovery of 1,2,4-Oxadiazole Derivatives Containing Haloalkyl as Potential Acetylcholine Receptor Nematicides. [PDF]

Int J Mol Sci, 2023
Luo L, Ou Y, Zhang Q, Gan X.
europepmc   +1 more source

Molecular docking and molecular dynamics simulation studies of inhibitor candidates against Anopheles gambiae 3-hydroxykynurenine transaminase and implications on vector control

Heliyon
Isoxazole and oxadiazole derivatives inhibiting 3-hydroxykynurenine transaminase (3HKT) are potential larvicidal candidates. This study aims to identify more suited potential inhibitors of Anopheles gambiae 3HKT (Ag3HKT) through molecular docking and ...
Eunice O. Adedeji, Olubanke O. Ogunlana, Gbolahan O. Oduselu, Rainer Koenig, Ezekiel Adebiyi, Opeyemi S. Soremekun, Segun Fatumo   +6 more
doaj   +1 more source

Design, synthesis, and biological evaluation of a novel series of 1,2,4-oxadiazole inhibitors of SLACK potassium channels: Identification of in vitro tool VU0935685. [PDF]

Bioorg Med Chem, 2023
Qunies AM, Spitznagel BD, Du Y, David Weaver C, Emmitte KA.   +4 more
europepmc   +1 more source

Modes of Action of a Novel c-MYC Inhibiting 1,2,4-Oxadiazole Derivative in Leukemia and Breast Cancer Cells. [PDF]

Molecules, 2023
Zhou M, Boulos JC, Omer EA, Klauck SM, Efferth T.   +4 more
europepmc   +1 more source

Identification of a 1,2,4-Oxadiazole with Potent and Specific Activity against Clostridioides difficile, the Causative Bacterium of C. difficile Infection, an Urgent Public Health Threat. [PDF]

J Med Chem, 2023
Barbachyn MR.
europepmc   +1 more source