Results 101 to 110 of about 40,557 (208)

Synthesis of Some New Heterocyclic Fused Rings Compounds Based on 5-Aryl-1,3,4-Oxadiazole

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
The work includes synthesis and characterization of some new heterocyclic compounds, as flow: The compound (3) (5-(4-chlorophenyl) -2-hydrazinyl-1,3,4-oxadiazole was synthesized by using two methods; the first method includes the direct reaction between
Zahra Mohammed Abbas, Dhuha Faruq Hussain, Raied Mustafa Shakir   +2 more
doaj  

Synthesis, characterisation and mesomorphic behaviours of non-symmetrically substituted 1,2,4- and 1,3,4-oxadiazole derivatives

, 2017
Two series of non-symmetrically substituted bent-core mesogens derived from the central 3,5 and 2,5 cores of the 1,2,4- and 1,3,4-oxadiazole derivatives, respectively, containing ether and ester linkage have been synthesised by several straightforward ...
Ali Hussein R. Al-Daraji (3135585), Mazin M. Abdul Razzaq Al-Obaidy (3135582), Ivan Hameed R. Tomi (3135588)   +2 more
core   +1 more source

Molecular docking and molecular dynamics simulation studies of inhibitor candidates against Anopheles gambiae 3-hydroxykynurenine transaminase and implications on vector control

Heliyon
Isoxazole and oxadiazole derivatives inhibiting 3-hydroxykynurenine transaminase (3HKT) are potential larvicidal candidates. This study aims to identify more suited potential inhibitors of Anopheles gambiae 3HKT (Ag3HKT) through molecular docking and ...
Eunice O. Adedeji, Olubanke O. Ogunlana, Gbolahan O. Oduselu, Rainer Koenig, Ezekiel Adebiyi, Opeyemi S. Soremekun, Segun Fatumo   +6 more
doaj   +1 more source

Synthesis and Antibacterial Activity of 1,3,4-Oxadiazole and 1,2,4-Triazole Derivatives of Salicylic Acid and its Synthetic Intermediates [PDF]

, 2015
Eight compounds 2–9 have been synthesized starting from salicylic acid, two of them (7 and 9) are novel. The four final products namely: 5-(2-hydroxy phenyl)-1,3,4-oxadiazole-2-thione 4, 3-(2-hydroxy phenyl)-1H-1,2,4-triazole-5-thiol 6, 3-(2-hydroxy ...
Khiati, Z, Guessas, B, Othman, AA
core  

Focused microwave irradiation-assisted synthesis of N-cyclohexyl-1,2,4-oxadiazole derivatives with antitumor activity

, 2019
A facile synthesis of 3,5-disubstituted 1,2,4-oxadiazole derivatives under focused microwave irradiation (FMWI) is reported. Arylamidoximes 1a–i and dicyclohexylcarbodiimide (DCC) were carried out in DMF under FMWI to obtain 1,2,4-oxadiazoles 2a–i in 61 ...
Roberto Nicolete (90567), Vanessa Pinheiro Gonçalves Ferreira (5829473), Ronaldo Nascimento de Oliveira (5829482), Cláudia do Ó Pessoa (5829479), Héverton Mendes Araújo (5829476), Franciane Gonçalves dos Santos (5829470), Valentina Nascimento Melo de Oliveira (5829467)   +6 more
core   +1 more source

Asymmetric Design of Bipolar Host Materials with Novel 1,2,4-Oxadiazole Unit in Blue Phosphorescent Device

, 2016
The intrinsic asymmetry of 1,2,4-oxadiazole was utilized to synthesize three isomers, DCzmOXD-1, DCzmOXD-2, and mCzmOXD, and high triplet energies over 2.80 eV made them good candidates for host materials in blue OLEDs. The best efficiencies of 23.0 cd A–
Liang-Sheng Liao (1586392), Lin-Song Cui (1594984), Zuo-Quan Jiang (1594987), Cheng Zhong (573294), Qian Li (114642)   +4 more
core   +1 more source

The study on 3- phenoxy-1,2,4-oxadiazole derivatives as novel inhibitors for the STAT3 pathways.

, 2012
학위논문 (석사)-- 서울대학교 대학원 : 의과학과, 2012. 2. 예상규.STAT3 often found constitutively activated in various human cancer. It is well established that persistently activated STAT3 promotes its downstream genes involved in cell proliferation, survival and growth ...
최지원
core  

Molecular Periphery Design Allows Control of the New Nitrofurans Antimicrobial Selectivity

Molecules
A series of 13 new 3-substituted 5-(5-nitro-2-furyl)-1,2,4-oxadiazoles was synthesized from different aminonitriles. All compounds were screened in the disc diffusion test at a 100 μg/mL concentration to determine the bacterial growth inhibition zone ...
Lyubov Vinogradova, Alexey Lukin, Kristina Komarova, Maxim Zhuravlev, Artem Fadeev, Mikhail Chudinov, Elizaveta Rogacheva, Lyudmila Kraeva, Maxim Gureev, Yuri Porozov, Marine Dogonadze, Tatiana Vinogradova   +11 more
doaj   +1 more source

Discovery of 1,2,4-Oxadiazole Derivatives Containing Haloalkyl as Potential Acetylcholine Receptor Nematicides. [PDF]

Int J Mol Sci, 2023
Luo L, Ou Y, Zhang Q, Gan X.
europepmc   +1 more source

Design, synthesis, and biological evaluation of a novel series of 1,2,4-oxadiazole inhibitors of SLACK potassium channels: Identification of in vitro tool VU0935685. [PDF]

Bioorg Med Chem, 2023
Qunies AM, Spitznagel BD, Du Y, David Weaver C, Emmitte KA.   +4 more
europepmc   +1 more source