Results 111 to 120 of about 31,516 (214)

Molecular Periphery Design Allows Control of the New Nitrofurans Antimicrobial Selectivity

Molecules
A series of 13 new 3-substituted 5-(5-nitro-2-furyl)-1,2,4-oxadiazoles was synthesized from different aminonitriles. All compounds were screened in the disc diffusion test at a 100 μg/mL concentration to determine the bacterial growth inhibition zone ...
Lyubov Vinogradova, Alexey Lukin, Kristina Komarova, Maxim Zhuravlev, Artem Fadeev, Mikhail Chudinov, Elizaveta Rogacheva, Lyudmila Kraeva, Maxim Gureev, Yuri Porozov, Marine Dogonadze, Tatiana Vinogradova   +11 more
doaj   +1 more source

A Novel 3-meta-Pyridine-1,2,4-oxadiazole Derivative of Glycyrrhetinic Acid as a Safe and Promising Candidate for Overcoming P-Glycoprotein-Mediated Multidrug Resistance in Tumor Cells. [PDF]

ACS Omega, 2023
Moralev AD, Salomatina OV, Chernikov IV, Salakhutdinov NF, Zenkova MA, Markov AV.   +5 more
europepmc   +1 more source

Preparation of crosslinked 1,2,4-oxadiazole polymer [PDF]

, 1981
New crosslinked 1,2,4-oxadiazole elastomers were prepared by thermally condensing a monomer having the formula H2N(HON)C-R-Q, wherein Q is a triazine ring-forming group such as nitrile or amidine or a mixture of such group with amidoxime, or a mixture of
Shalhoub, I. M., Kwong, H., Rosser, R. W.   +2 more
core   +1 more source

Synthesis, enzyme inhibition and molecular docking studies of novel 1,2,4-oxadiazole thioether derivatives [PDF]

A new series of thioethers containing a 1,2,4-oxadiazole ring were synthesized by the modified Riemschneider reaction. The corresponding thiocyanate derivatives of 1,2,4-oxadiazoles were obtained in good yields by the reaction of 3-aryl-5-chloromethyl-1 ...
Noma, Samir Abbas Ali, Ölmez, Nevin Arıkan, Kaya, Yunus, Osman, Bilgen   +3 more
core   +1 more source

Simple and Efficient Synthesis of Diamino Derivatives of bis-1,2,4-oxadiazole via Tandem Staudinger/aza-Wittig Reaction. [PDF]

Curr Org Synth, 2023
Xie H, Hu QQ, Zhang YL, Qin XT, Li L.
europepmc   +1 more source

The study on 3- phenoxy-1,2,4-oxadiazole derivatives as novel inhibitors for the STAT3 pathways. [PDF]

, 2012
학위논문 (석사)-- 서울대학교 대학원 : 의과학과, 2012. 2. 예상규.STAT3 often found constitutively activated in various human cancer. It is well established that persistently activated STAT3 promotes its downstream genes involved in cell proliferation, survival and growth ...
최지원
core  

3-(3-Azabicyclo[2, 2, 1]heptan-2-yl)-1,2,4-oxadiazoles as Novel Potent DPP-4 Inhibitors to Treat T2DM

Pharmaceuticals
Background: Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disease with global implications, necessitating effective management strategies.
Tatiana V. Zinevich, Ivan O. Maslov, Olga G. Kirichenko, Sergey V. Shorshnev, Maxim A. Gureev, Fedor M. Dolgushin, Yuri B. Porozov, Vladimir M. Trukhan   +7 more
doaj   +1 more source

New 1,2,4-oxadiazole derivatives with positive mGlu₄ receptor modulation activity and antipsychotic-like properties. [PDF]

J Enzyme Inhib Med Chem, 2022
Stankiewicz A, Kaczorowska K, Bugno R, Kozioł A, Paluchowska MH, Burnat G, Chruścicka B, Chorobik P, Brański P, Wierońska JM, Duszyńska B, Pilc A, Bojarski AJ.   +12 more
europepmc   +1 more source

Boosting the Energetic Performance of Trinitromethyl-1,2,4-oxadiazole Moiety by Increasing Nitrogen-Oxygen in the Bridge. [PDF]

Int J Mol Sci, 2022
Chen P, Dou H, He C, Pang S.
europepmc   +1 more source

New Marine-Inspired Oxadiazole Derivatives for Use Against Pancreatic Ductal Adenocarcinoma

Marine Drugs
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest malignancies, with limited effective therapeutic options due to late diagnosis, aggressive progression, and rapid development of drug resistance.
Camilla Pecoraro, Daniela Carbone, Fares Hezam Mohammed Al Ostoot, Mahrou Vahabi, Giulia Lencioni, Patrizia Diana, Elisa Giovannetti, Barbara Parrino   +7 more
doaj   +1 more source