Results 121 to 130 of about 40,557 (208)

New 1,2,4-oxadiazole derivatives with positive mGlu₄ receptor modulation activity and antipsychotic-like properties. [PDF]

J Enzyme Inhib Med Chem, 2022
Stankiewicz A, Kaczorowska K, Bugno R, Kozioł A, Paluchowska MH, Burnat G, Chruścicka B, Chorobik P, Brański P, Wierońska JM, Duszyńska B, Pilc A, Bojarski AJ.   +12 more
europepmc   +1 more source

Simple and Efficient Synthesis of Diamino Derivatives of bis-1,2,4-oxadiazole via Tandem Staudinger/aza-Wittig Reaction. [PDF]

Curr Org Synth, 2023
Xie H, Hu QQ, Zhang YL, Qin XT, Li L.
europepmc   +1 more source

Boosting the Energetic Performance of Trinitromethyl-1,2,4-oxadiazole Moiety by Increasing Nitrogen-Oxygen in the Bridge. [PDF]

Int J Mol Sci, 2022
Chen P, Dou H, He C, Pang S.
europepmc   +1 more source

Synthesis and Bioactivity Evaluation of a Novel 1,2,4-Oxadiazole Derivative in vitro and in 3×Tg Mice. [PDF]

Drug Des Devel Ther, 2022
Luo Z, Wang Y, Pang S, Gao S, Liu N, Gao X, Zhang L, Qi X, Yang Y, Zhang L.   +9 more
europepmc   +1 more source

Synthesis of Some 3-Aryl-1,2,4-oxadiazoles Carrying a Protected L-Alanine Side Chain

Journal of the Brazilian Chemical Society, 1998
The synthesis of some 1,2,4-oxadiazole derivatives (4a-d) starting from arylamidoximes 1a-d and N-t-butoxycarbonyl-O-benzyl-L-aspartic acid is described. The structures of these new products have been determined by spectroscopic methods.
Melo Sebastião J. de, Sobral Antônio D., Lopes Heron de Lima, Srivastava R.M.   +3 more
doaj  

Discovery of 3-phenyl-1,2,4-oxadiazole derivatives as a new class of SARS-CoV-2 main protease inhibitors. [PDF]

Bioorg Med Chem Lett, 2023
Guo N, Huang C, Qiao J, Li Y, Wang Y, Xia A, Zhang G, Fang Z, You J, Li L.   +9 more
europepmc   +1 more source

Evaluation of the in vitro activity of synthetic derivatives of N-cyclohexyl-3-(3-methylphenyl)-1,2,4-oxadiazole-5-amine on the strain y of Trypanosoma cruzi and an in vivo toxicity study. [PDF]

Mem Inst Oswaldo Cruz
Rocha YM, Ribeiro LR, de Moura GA, Chaves MM, Rodrigues JPV, Magalhães EP, Barbosa SICG, Frota LS, de Morais SM, da Silva WMB, de Oliveira VNEM, de Oliveira RN, Martins AMC, Nicolete R.   +13 more
europepmc   +1 more source

Design, Synthesis and Antifungal/Nematicidal Activity of Novel 1,2,4-Oxadiazole Derivatives Containing Amide Fragments. [PDF]

Int J Mol Sci, 2022
Liu D, Luo L, Wang Z, Ma X, Gan X.
europepmc   +1 more source

Design and Synthesis of 1,2,4-Oxadiazole Derivatives as Non-Steroidal 5 Alpha-Reductase Inhibitors

, 2009
The purpose of this study was to synthesize compounds in which the 1,2,4- oxadiazole moiety replaced the amide bond of ONO3805 and to evaluate its 5 alpha-reductase inhibitory activity as a potential benign prostatic hyperplasia therapeutic target.
CHERN, JI-WANG, 陳基旺
core  

Synthesis and Antifungal Activity of 1,2,4-Oxadiazole Derivatives. [PDF]

Molecules
Yu L, Yang K, Yao L, Wang N, Kang H, Yao G, Li X, Qin B.   +7 more
europepmc   +1 more source