Results 111 to 120 of about 4,245 (200)

Identification of a 1,2,4-Oxadiazole with Potent and Specific Activity against Clostridioides difficile, the Causative Bacterium of C. difficile Infection, an Urgent Public Health Threat. [PDF]

J Med Chem, 2023
Barbachyn MR.
europepmc   +1 more source

Progress toward phidianidine analogues containing a 1,2,3-triazole ring [PDF]

, 2017
Phidianidines are a class of compound that has been extracted from the sea mollusk Phidianis militaris. These compounds have been shown to exhibit a variety of useful properties such as antihistamine effects, anti-cancer activity, agonism of the µ-opioid
King, Dillon, Laws, David, III, Wakefield, Bryan H   +2 more
core   +1 more source

New Marine-Inspired Oxadiazole Derivatives for Use Against Pancreatic Ductal Adenocarcinoma

Marine Drugs
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest malignancies, with limited effective therapeutic options due to late diagnosis, aggressive progression, and rapid development of drug resistance.
Camilla Pecoraro, Daniela Carbone, Fares Hezam Mohammed Al Ostoot, Mahrou Vahabi, Giulia Lencioni, Patrizia Diana, Elisa Giovannetti, Barbara Parrino   +7 more
doaj   +1 more source

A Novel 3-meta-Pyridine-1,2,4-oxadiazole Derivative of Glycyrrhetinic Acid as a Safe and Promising Candidate for Overcoming P-Glycoprotein-Mediated Multidrug Resistance in Tumor Cells. [PDF]

ACS Omega, 2023
Moralev AD, Salomatina OV, Chernikov IV, Salakhutdinov NF, Zenkova MA, Markov AV.   +5 more
europepmc   +1 more source

Simple and Efficient Synthesis of Diamino Derivatives of bis-1,2,4-oxadiazole via Tandem Staudinger/aza-Wittig Reaction. [PDF]

Curr Org Synth, 2023
Xie H, Hu QQ, Zhang YL, Qin XT, Li L.
europepmc   +1 more source

Synthesis of 1,2,4-Oxadiazoles Based on Diffractaic Acid

Molbank
Diffractic acid 1 is a secondary metabolite of depside lichens with antibacterial and insecticidal properties, and anticancer, hepatoprotective and antiviral activities.
Aleksandr Filimonov, Anastasia Diveikina, Yuri Gatilov, Olga Luzina, Nariman Salakhutdinov   +4 more
doaj   +1 more source

New 1,2,4-oxadiazole derivatives with positive mGlu₄ receptor modulation activity and antipsychotic-like properties. [PDF]

J Enzyme Inhib Med Chem, 2022
Stankiewicz A, Kaczorowska K, Bugno R, Kozioł A, Paluchowska MH, Burnat G, Chruścicka B, Chorobik P, Brański P, Wierońska JM, Duszyńska B, Pilc A, Bojarski AJ.   +12 more
europepmc   +1 more source

Novel Ag(I)-based 1,2,4-oxadiazole complexes: Synthesis, X-ray crystal structure, and biological evaluation as anticancer candidates [PDF]

Funding: This work was supported by the Deanship of Scientific Research, Vice Presidency for Graduate Studies and Scientific Research, King Faisal University, Saudi Arabia (Project No.
Abd Al Moaty, Mohamed N., Abdel-Hamid, Hamida, Alashhab, Rabia E., Ayoup, Mohammed Salah, Cordes, David Bradford, Ghareeb, Doaa A., Kassab, Asmaa E., Masoud, Aliaa, McKay, Aidan, Soliman, Saied M.   +9 more
core   +1 more source

N-Acetonitrile functionalized 3-nitrotriazole: Precursor to nitrogen rich stable and insensitive energetic materials

Energetic Materials Frontiers
In the field of energetic materials, prime attention has been given to the synthesis of environmentally compatible energetic materials having an adequate balance between energy and stability.
Prachi Bhatia, Peddapothula Sahithi Priya, Priyanka Das, Dheeraj Kumar   +3 more
doaj   +1 more source

Boosting the Energetic Performance of Trinitromethyl-1,2,4-oxadiazole Moiety by Increasing Nitrogen-Oxygen in the Bridge. [PDF]

Int J Mol Sci, 2022
Chen P, Dou H, He C, Pang S.
europepmc   +1 more source