Cu(OH)x: Clay Catalyst Promoted Synthesis of 4,5-dihydro-1,2,4-oxadiazole at Room Temperature [PDF]
Orbital: The Electronic Journal of Chemistry, 2017 An easy and efficient scheme is described designed for the preparation of 4,5-dihydro-1,2,4-oxadiazole using recyclable Cu(OH)x-Clay heterogeneous catalyst at room temperature.
Bashir Ahmad Dar +3 more
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Dysregulation of Mycobacterium marinum ESX-5 Secretion by Novel 1,2,4-oxadiazoles
Biomolecules, 2023 The ESX-5 secretion system is essential for the viability and virulence of slow-growing pathogenic mycobacterial species. In this study, we identified a 1,2,4-oxadiazole derivative as a putative effector of the ESX-5 secretion system.
Vien Q. T. Ho +8 more
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Synthesis of Various 3-Substituted 1,2,4-Oxadiazole-Containing Chiral β3- and α-Amino Acids from Fmoc-Protected Aspartic Acid [PDF]
, 2016 Various 3-substituted chiral 1,2,4-oxadiazole-containing Fmoc-β3- and -α-amino acids were synthesized from Fmoc-(l or d)-Asp(OtBu)-OH and Fmoc-l-Asp-OtBu, respectively, in three steps (i.e., condensation of an aspartyl derivative with differentially ...
Jean Martinez (150107) +3 more
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Recent advances on the nitrogen-rich 1,2,4-oxadiazole-azoles-based energetic materials
Defence Technology, 2022 This review covers recent advances in the synthesis and energetic performance of nitrogen-rich 1,2,4-oxadiazole-azoles-based energetic materials. These materials comprise of 1,2,4-oxadiazole subunit as a key structural motif linked to different nitrogen ...
Wen-Li Cao +4 more
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Synthesis, Biological Activity, and Toxicity to Zebrafish Embryo of Benzamides Substituted with 1,2,4-Oxadiazole-Linked Pyrazole [PDF]
, 2023 To explore novel pesticidal lead compounds with potential activity, a series of new benzamide compounds substituted with 1,2,4-oxadiazole-linked pyrazole were designed and synthesized based on the active substructure splice principle.
Sen Yang (88300) +17 more
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Biomedicines, 2023 Benzofuran, 1,3,4-oxadiazole, and 1,2,4-triazole are privileged heterocyclic moieties that display the most promising and wide spectrum of biological activities against a wide variety of diseases. In the current study, benzofuran-1,3,4-oxadiazole BF1–BF7
Ali Irfan +9 more
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Room Temperature Synthesis of Bioactive 1,2,4-Oxadiazoles
International Journal of Molecular Sciences, 2023 1,2,4-Oxadiazole is an essential motif in drug discovery represented in many experimental, investigational, and marketed drugs. This review covers synthetic methods that allow the conversion of different types of organic compounds into 1,2,4-oxadiazole at ambient temperature and the practical application of the latter approaches for the preparation of ...
Sergey V. Baykov +4 more
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Therapeutic potential of oxadiazole or furadiazole containing compounds
BMC Chemistry, 2020 As we know that, Oxadiazole or furadi azole ring containing derivatives are an important class of heterocyclic compounds. A heterocyclic five-membered ring that possesses two carbons, one oxygen atom, two nitrogen atoms, and two double bonds is known as ...
Ankit Siwach, Prabhakar Kumar Verma
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Synthesis and Study of Some 4-Chlorophenoxy Methyl Substituted amido1,3,4-Oxadiazoles, 1,3,4-Thiadiazoles and 1,2,4-Triazoles from 4-Chloro phenoxy acetic acid [PDF]
مجلة التربية والعلم, 2013 : In this paper the synthesis of some substituted 1,3,4-oxadiazole, 1,3,4-thiadiazoles and 1,2,4-triazoles is reported. 4-Chlorophenol was treated with chloroacetic acid to give 4-chlorophenoxy acetic acid (C1) which was reacted with thionyl chloride ...
Mudhar A. Othman, Khalid M. Daoud
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Mass Spectra of 1,2,4-Oxadiazole-5-thiones and 1,2,4-Thiadiazole-5-ones [PDF]
, 1992 The mass spectra of 3,4-disubstituted-1,2,4-oxadiazole -5(4H)-thione and 3,4-disubstituted-1,2,4-thiadiazole-5(4H) -ones have been studied. The rearrangement of molecular ion of 1,2,4-oxadiazole-5-thiones to 1,2,4-thiadiazole-5-ones was proposed.
Ağırbaş, Hüseyin
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