Results 21 to 30 of about 101,287 (245)

Synthesis and Antifungal Activity of 1,2,4-Oxadiazole Derivatives. [PDF]

Molecules
1,2,4-Oxadiazole derivatives containing anisic acid or cinnamic acid were designed and synthesized, which were expected to be an effective Succinate dehydrogenase (SDH) inhibitor, and their structures were characterized by 1H NMR, 13C NMR, and ESI-MS. The antifungal activity of the compounds against plant pathogenic fungi was screened by the mycelial ...
Yu L, Yang K, Yao L, Wang N, Kang H, Yao G, Li X, Qin B.   +7 more
europepmc   +4 more sources

A Family of Energetic Materials Based on 1,2,4-Oxadiazole and 1,2,5-Oxadiazole Backbones With Low Insensitivity and Good Detonation Performance

Frontiers in Chemistry, 2020
Design and synthesis of new compounds with both high detonation performances and good safety properties have always been a formidable task in the field of energetic materials.
Qi Xue, Fu-qiang Bi, Jun-lin Zhang, Zi-jun Wang, Zi-jun Wang, Lian-jie Zhai, Lian-jie Zhai, Huan Huo, Bo-zhou Wang, Sheng-yong Zhang, Sheng-yong Zhang   +10 more
doaj   +2 more sources

Cu(OH)x: Clay Catalyst Promoted Synthesis of 4,5-dihydro-1,2,4-oxadiazole at Room Temperature

Orbital: The Electronic Journal of Chemistry, 2017
An easy and efficient scheme is described designed for the preparation of 4,5-dihydro-1,2,4-oxadiazole using recyclable Cu(OH)x-Clay heterogeneous catalyst at room temperature.
Bashir Ahmad Dar, Zahed Zaheer, Samreen Fatema, Mazahar Farooqui   +3 more
doaj   +5 more sources

Syntheses and Promising Properties of Dense Energetic 5,5′‐Dinitramino‐3,3′‐azo‐1,2,4‐oxadiazole and Its Salts

Angewandte Chemie - International Edition, 2016
A planar energetic molecule with high density, 5,5′-dinitramino-3,3′-azo-1,2,4-oxadiazole (4), was obtained by the nitration of 5,5′-diamino-3,3′-azo-1,2,4-oxadiazole using 100% nitric acid. In addition, selected nitrogen-rich salts were prepared.
Yongxing Tang, Haixiang Gao, Lauren A Mitchell   +2 more
exaly   +2 more sources

Dysregulation of Mycobacterium marinum ESX-5 Secretion by Novel 1,2,4-oxadiazoles

Biomolecules, 2023
The ESX-5 secretion system is essential for the viability and virulence of slow-growing pathogenic mycobacterial species. In this study, we identified a 1,2,4-oxadiazole derivative as a putative effector of the ESX-5 secretion system.
Vien Q. T. Ho, Mark K. Rong, Eva Habjan, Samantha D. Bommer, Thang V. Pham, Sander R. Piersma, Wilbert Bitter, Eelco Ruijter, Alexander Speer   +8 more
doaj   +1 more source

Synthesis of Various 3-Substituted 1,2,4-Oxadiazole-Containing Chiral β³- and α-Amino Acids from Fmoc-Protected Aspartic Acid

, 2016
Various 3-substituted chiral 1,2,4-oxadiazole-containing Fmoc-β3- and -α-amino acids were synthesized from Fmoc-(l or d)-Asp(OtBu)-OH and Fmoc-l-Asp-OtBu, respectively, in three steps (i.e., condensation of an aspartyl derivative with differentially ...
Jean Martinez (150107), Pierre Fulcrand (2498626), Jean-François Hernandez (2701363), Abdallah Hamzé, (2701360)   +3 more
core   +3 more sources

An Exploration of the Inhibitory Mechanism of Rationally Screened Benzofuran-1,3,4-Oxadiazoles and-1,2,4-Triazoles as Inhibitors of NS5B RdRp Hepatitis C Virus through Pharmacoinformatic Approaches

Biomedicines, 2023
Benzofuran, 1,3,4-oxadiazole, and 1,2,4-triazole are privileged heterocyclic moieties that display the most promising and wide spectrum of biological activities against a wide variety of diseases. In the current study, benzofuran-1,3,4-oxadiazole BF1–BF7
Ali Irfan, Shah Faisal, Sajjad Ahmad, Muhammad Jawwad Saif, Ameer Fawad Zahoor, Samreen Gul Khan, Jamila Javid, Sami A. Al-Hussain, Muhammed Tilahun Muhammed, Magdi E. A. Zaki   +9 more
doaj   +1 more source

Room Temperature Synthesis of Bioactive 1,2,4-Oxadiazoles

International Journal of Molecular Sciences, 2023
1,2,4-Oxadiazole is an essential motif in drug discovery represented in many experimental, investigational, and marketed drugs. This review covers synthetic methods that allow the conversion of different types of organic compounds into 1,2,4-oxadiazole at ambient temperature and the practical application of the latter approaches for the preparation of ...
Sergey V. Baykov, Anton A. Shetnev, Artem V. Semenov, Svetlana O. Baykova, Vadim P. Boyarskiy   +4 more
openaire   +2 more sources

Therapeutic potential of oxadiazole or furadiazole containing compounds

BMC Chemistry, 2020
As we know that, Oxadiazole or furadi azole ring containing derivatives are an important class of heterocyclic compounds. A heterocyclic five-membered ring that possesses two carbons, one oxygen atom, two nitrogen atoms, and two double bonds is known as ...
Ankit Siwach, Prabhakar Kumar Verma
doaj   +1 more source

Synthesis and Study of Some 4-Chlorophenoxy Methyl Substituted amido1,3,4-Oxadiazoles, 1,3,4-Thiadiazoles and 1,2,4-Triazoles from 4-Chloro phenoxy acetic acid [PDF]

مجلة التربية والعلم, 2013
: In this paper the synthesis of some substituted 1,3,4-oxadiazole, 1,3,4-thiadiazoles and 1,2,4-triazoles is reported. 4-Chlorophenol was treated with chloroacetic acid to give 4-chlorophenoxy acetic acid (C1) which was reacted with thionyl chloride ...
Mudhar A. Othman, Khalid M. Daoud
doaj   +1 more source