Results 41 to 50 of about 101,287 (245)

Synthesis of Fluorinated Bent-Core Mesogens (BCMs) Containing the 1,2,4-Oxadiazole Ring [PDF]

, 2015
New fluorinated bent-core mesogens containing the 1,2,4-oxadiazole or 1,2,4-triazole nucleus have been synthesized taking advantage of the ANRORC (Addition of Nucleophile, Ring-Opening, Ring-Closure) reactivity of 5-perfluoroalkyl-1,2,4-oxadiazoles ...
Ivana Pibiri, PALUMBO PICCIONELLO, Antonio, Calabrese, Alessandro, Antonio Palumbo Piccionello, Alessandro Calabrese, Silvestre Buscemi, PIBIRI, Ivana, Andrea Pace, BUSCEMI, Silvestre, PACE, Andrea, Valentina Giacalone, Giacalone, Valentina   +11 more
core   +1 more source

Strategic integration of 1,2,4-oxadiazole and nitramino-triazole frameworks for high-energy-density materials

Defence Technology
Developing high-energy-density materials (HEDMs) with balanced energy and safety performance remains a significant challenge in energetic materials. This study presents the synthesis and systematic characterization of two novel high-performance energetic
Ziyi Xu, Caijin Lei, Xuezhi Yu, Jie Tang, Wei Hu, Hongwei Yang, Guangbin Cheng   +6 more
doaj   +1 more source

SET activation of nitroarenes by 2-azaallyl anions as a straightforward access to 2,5-dihydro-1,2,4-oxadiazoles

Nature Communications, 2021
Oxadiazoles are five-membered ring heterocycles comprising an oxygen and two nitrogens, and those with the 1,2,4-oxadiazole skeleton are of interest due to their prevalence in biologically active compounds.
Dong Zou, Lishe Gan, Fan Yang, Huan Wang, Youge Pu, Jie Li, Patrick J. Walsh   +6 more
doaj   +1 more source

Tetrabutylammonium 2-[2,5-dimethyl-3-(4-nitrophenyl)-2,3-dihydro-1,2,4-oxadiazolium-4-yl]nonahydro-closo-decaborate

Acta Crystallographica Section E, 2012
The title ionic compound, C16H36N+·C10H20B10N3O3−, consists of a tetrabutylammonium cation and a closo-decaborate cluster anion, which is bound to the substituted 2,3-dihydro-1,2,4-oxadiazole ring through a B—N bond [1.540 ...
Aleksey L. Mindich, Anna V. Pavlishchuk, Nadezhda A. Bokach, Galina L. Starova, Konstantin Yu. Zhizhin   +4 more
doaj   +1 more source

Synthesis and characterization of 5-aryl-1,3,4-oxadiazole-2(3h)thione derivatives

Journal of Applied Pharmaceutical Research, 2020
1,3,4-oxadiazoles represent a class of heterocyclic five membered compounds it contain two nitrogen and one oxygen of great importance in Pharmaceutical chemistry. This nucleus show four isomeric forms 1,2,4-oxadiazole,1,3,4-oxadiazole, 1,2,5-oxadiazole,
Shailesh Pathak, Sharad Sharma, Vinay Pathak, Mahesh Prasad   +3 more
doaj   +1 more source

Thiophene-Substituted 1,2,4-Oxadiazoles and Oxadiazines

Phosphorus, Sulfur, and Silicon and the Related Elements, 2007
Twenty one new thiophene-substituted 1,2,4-oxadiazol-5(4H)-ones, 1,2,4-oxadiazol-5(4H)-thiones, and 1,2,4-oxadiazin-5(6H)-ones were synthesized by the reaction of thiophene-ring substituted amidoximes with ethyl chloroformate, thiophosgene, and chloroacetylchloride, respectively.
Dürüst, Yaşar, Altuğ, Cevher, Kılıç, Ferdi   +2 more
openaire   +1 more source

Synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles from 2-(2,3-dimethylphenyl amino) benzoic acid [PDF]

مجلة التربية والعلم, 2009
In this paper the synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles was achieved. 2-(2,3-dimethyl phenyl amino) benzoic acid was esterified to its ethyl ester by its reaction with absolute ethanol in presence of ...
Khalid Daoud, Shereen Mohamed, Nagham Al-Niami   +2 more
doaj   +1 more source

New 1,2,4-Oxadiazole Nortopsentin Derivatives with Cytotoxic Activity

Marine Drugs, 2019
New analogs of nortopsentin, a natural 2,4-bis(3′-indolyl)imidazole alkaloid, in which the central imidazole ring of the natural lead was replaced by a 1,2,4-oxadiazole moiety, and in which a 7-azaindole portion substituted the original indole moiety ...
S. Cascioferro, A. Attanzio, Veronica Di Sarno, Simona Musella, L. Tesoriere, G. Cirrincione, P. Diana, B. Parrino   +7 more
semanticscholar   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Síntese e caracterização de novos materiais funcionais contendo 1,2,4-oxadiazol, 1,3,4-oxadiazol e 1,2,3-triazol [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2014Neste trabalho de tese de doutorado são apresentadas as sínteses ecaracterizações de três novas ...
Girotto, Edivandro
core