Results 51 to 60 of about 40,557 (208)

SET activation of nitroarenes by 2-azaallyl anions as a straightforward access to 2,5-dihydro-1,2,4-oxadiazoles

open access: yesNature Communications, 2021
Oxadiazoles are five-membered ring heterocycles comprising an oxygen and two nitrogens, and those with the 1,2,4-oxadiazole skeleton are of interest due to their prevalence in biologically active compounds.
Dong Zou   +6 more
doaj   +1 more source

A novel synthesis of 1,2,4-oxadiazoles and isoxazoles

open access: yesTetrahedron, 2014
A novel synthesis of 1,2,4-oxadiazoles and isoxazoles is described by utilizing the reactions between amidoximes and α,β-alkynic aldehydes and/or ketones. Conjugate addition products, obtained from amidoximes and α,β-alkynic aldehydes and/or ketones, afford 1,2,4-oxadiazoles and isoxazoles when treated with bases and acids, respectively.
Kivrak, Arif, Zora, Metin
openaire   +4 more sources

Harnessing benzamides as plant stress inhibitors, growth promoters and in management of crop resilience—A review

open access: yesPlant Biology, EarlyView.
Benzamides boost crop resilience by inhibiting poly(ADP‐ribose) polymerase (PARP) to enhance stress tolerance and, through their antimicrobial, herbicidal, and insecticidal derivatives, they offer broad protection for sustainable crop improvement. Abstract Benzamides have emerged as potent stress inhibitors and growth promoters in plant biotechnology ...
M. J. Koetle, T. E. Motaung, S. O. Amoo
wiley   +1 more source

Synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles from 2-(2,3-dimethylphenyl amino) benzoic acid [PDF]

open access: yesمجلة التربية والعلم, 2009
In this paper the synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles was achieved. 2-(2,3-dimethyl phenyl amino) benzoic acid was esterified to its ethyl ester by its reaction with absolute ethanol in presence of ...
Khalid Daoud   +2 more
doaj   +1 more source

Thiophene-Substituted 1,2,4-Oxadiazoles and Oxadiazines

open access: yesPhosphorus, Sulfur, and Silicon and the Related Elements, 2007
Twenty one new thiophene-substituted 1,2,4-oxadiazol-5(4H)-ones, 1,2,4-oxadiazol-5(4H)-thiones, and 1,2,4-oxadiazin-5(6H)-ones were synthesized by the reaction of thiophene-ring substituted amidoximes with ethyl chloroformate, thiophosgene, and chloroacetylchloride, respectively.
Dürüst, Yaşar   +2 more
openaire   +1 more source

Síntese de cristais líquidos isônicos e/ou discóticos contendo os heterociclos 1,2,4- E 1,3,4- oxadiazol [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2013.A presente dissertacao traz o estudo realizado com moleculas derivadas dos heterociclos 1,
Silva, Danilo Henrique da
core  

Energetic materials based on isocyanuric acid and 1,2,4-oxadiazole derivatives [PDF]

open access: yes, 2013
The synthesis and properties of explosive urea and triazine derivatives is investigated on behalf of the explosive parameters and the full characterization of the molecules.
Mayr, Norbert
core   +1 more source

Bis-Oxadiazole Assemblies as NO-Releasing Anticancer Agents

open access: yesPharmaceutics
Background: Malignant pleural mesothelioma (MPM) is an aggressive, asbestos-associated cancer characterized by dysregulated nitric oxide (NO) signaling and increased NO levels that facilitate tumor progression. Paradoxically, this aberrant NO environment
Egor M. Matnurov   +7 more
doaj   +1 more source

Cu(OH)x-clay catalyst promoted synthesis of 4,5-dihydro-1,2,4-oxadiazole at room temperature

open access: yesGreen Processing and Synthesis, 2018
An easy and efficient scheme is described and designed for the preparation of 4,5-dihydro-1,2,4-oxadiazole using recyclable Cu(OH)x-clay heterogeneous catalyst at room temperature.
Dar Bashir Ahmad   +3 more
doaj   +1 more source

Development of Benzothiophene–Bearing Bis–oxadiazole Derivatives for Potential Anticancer Targets: Evaluation of DFT, ADME–Tox, and In Silico Docking

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Innovative synthesis of a novel benzothiophene–based bis–oxadiazole derivatives. The structural characterization was performed using experimental and theoretical methods. Significant anticancer activity against selected cancer cell lines. Three derivatives showed good activity 7b, 7g and 7i with IC50 values 7.5 ± 1.04 and 9.5 ± 1.01 µg/mL.
Nagaraju Madala   +2 more
wiley   +1 more source

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