Results 51 to 60 of about 101,287 (245)

Cu(OH)x-clay catalyst promoted synthesis of 4,5-dihydro-1,2,4-oxadiazole at room temperature

Green Processing and Synthesis, 2018
An easy and efficient scheme is described and designed for the preparation of 4,5-dihydro-1,2,4-oxadiazole using recyclable Cu(OH)x-clay heterogeneous catalyst at room temperature.
Dar Bashir Ahmad, Zaheer Zahed, Fatema Samreen, Farooqui Mazahar   +3 more
doaj   +1 more source

A novel synthesis of 1,2,4-oxadiazoles and isoxazoles

Tetrahedron, 2014
A novel synthesis of 1,2,4-oxadiazoles and isoxazoles is described by utilizing the reactions between amidoximes and α,β-alkynic aldehydes and/or ketones. Conjugate addition products, obtained from amidoximes and α,β-alkynic aldehydes and/or ketones, afford 1,2,4-oxadiazoles and isoxazoles when treated with bases and acids, respectively.
Kivrak, Arif, Zora, Metin
openaire   +3 more sources

Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II

European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley   +1 more source

Síntese de materiais orgânicos funcionais derivados do heterociclo 1,2,4-oxadiazol [PDF]

, 2008
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.Este trabalho tem como objetivo geral a síntese de moléculas simétricas curvadas contendo o heterociclo 1,2,4 oxadiazol, bem como o ...
FERREIRA, Marli
core  

Bis-Oxadiazole Assemblies as NO-Releasing Anticancer Agents

Pharmaceutics
Background: Malignant pleural mesothelioma (MPM) is an aggressive, asbestos-associated cancer characterized by dysregulated nitric oxide (NO) signaling and increased NO levels that facilitate tumor progression. Paradoxically, this aberrant NO environment
Egor M. Matnurov, Irina A. Stebletsova, Alexander A. Larin, Jemma Arakelyan, Ivan V. Ananyev, Artem L. Gushchin, Leonid L. Fershtat, Maria V. Babak   +7 more
doaj   +1 more source

Síntese de cristais líquidos isônicos e/ou discóticos contendo os heterociclos 1,2,4- E 1,3,4- oxadiazol [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2013.A presente dissertacao traz o estudo realizado com moleculas derivadas dos heterociclos 1,
Silva, Danilo Henrique da
core  

Mass Spectra of 1,2,4-Oxadiazole-5-thiones and 1,2,4-Thiadiazole-5-ones

, 1992
The mass spectra of 3,4-disubstituted-1,2,4-oxadiazole -5(4H)-thione and 3,4-disubstituted-1,2,4-thiadiazole-5(4H) -ones have been studied. The rearrangement of molecular ion of 1,2,4-oxadiazole-5-thiones to 1,2,4-thiadiazole-5-ones was proposed.
Ağırbaş, Hüseyin
core   +1 more source

RuPhos Pd G4: A catalyst for Suzuki-Miyaura coupling reactions involving 1,2,4-oxadiazoles

Results in Chemistry
The 1,2,4-oxadiazole motif is highly significant in biological studies. An efficient Suzuki-Miyaura coupling methodology has been developed, catalyzed by RuPhos Pd G4, for 1,2,4-oxadiazole substrates This method achieves high yields and clean reactions ...
Deepak Kumar, Soumya Singh, Ganesh Jaysing Shinde, Suryakanta Dalai, Abhineet Vermaa, Girish Chandra Sharma, Mukesh Jangir   +6 more
doaj   +1 more source

π–π Noncovalent Interaction Involving 1,2,4- and 1,3,4-Oxadiazole Systems: The Combined Experimental, Theoretical, and Database Study

Molecules, 2021
A series of N-pyridyl ureas bearing 1,2,4- (1a, 2a, and 3a) and 1,3,4-oxadiazole moiety (1b, 2b, 3b) was prepared and characterized by HRMS, 1H and 13C NMR spectroscopy, as well as X-ray diffraction.
Sergey V. Baykov, Alexander S. Mikherdov, Alexander S. Novikov, Kirill K. Geyl, Marina V. Tarasenko, Maxim A. Gureev, Vadim P. Boyarskiy   +6 more
doaj   +1 more source

Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment.

European journal of medicinal chemistry, 2019
An expanded set of diversely substituted 1,2,4-oxadiazole-containing primary aromatic sulfonamides was synthesized and tested for inhibition of human carbonic anhydrase I, II, IX and XII isoforms.
M. Krasavin, A. Shetnev, T. Sharonova, S. Baykov, S. Kalinin, A. Nocentini, V. Sharoyko, G. Poli, T. Tuccinardi, S. Presnukhina, T. Tennikova, C. Supuran   +11 more
semanticscholar   +1 more source