Results 31 to 40 of about 4,245 (200)
Nature Communications, 2021 Oxadiazoles are five-membered ring heterocycles comprising an oxygen and two nitrogens, and those with the 1,2,4-oxadiazole skeleton are of interest due to their prevalence in biologically active compounds.
Dong Zou +6 more
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Synthesis and characterization of 5-aryl-1,3,4-oxadiazole-2(3h)thione derivatives
Journal of Applied Pharmaceutical Research, 2020 1,3,4-oxadiazoles represent a class of heterocyclic five membered compounds it contain two nitrogen and one oxygen of great importance in Pharmaceutical chemistry. This nucleus show four isomeric forms 1,2,4-oxadiazole,1,3,4-oxadiazole, 1,2,5-oxadiazole,
Shailesh Pathak +3 more
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A Fragment-Based Approach for the Development of G-Quadruplex Ligands: Role of the Amidoxime Moiety [PDF]
, 2018 G-quadruplex (G4) nucleic acid structures have been reported to be involved in several human pathologies, including cancer, neurodegenerative disorders and infectious diseases; however, G4 targeting compounds still need implementation in terms of drug ...
Butovskaya, Elena +7 more
core +2 more sources
Molecules, 2021 A series of N-pyridyl ureas bearing 1,2,4- (1a, 2a, and 3a) and 1,3,4-oxadiazole moiety (1b, 2b, 3b) was prepared and characterized by HRMS, 1H and 13C NMR spectroscopy, as well as X-ray diffraction.
Sergey V. Baykov +6 more
doaj +1 more source
Synthese von 1,2,4-Oxadiazolen, Cyclooctinen und Studien zur Synthese nicht-symmetrischer partiell-fluorierter DNTT [PDF]
, 2019 Der erste Teil dieser Arbeit beschreibt einen neuartigen Zugang zu 1,2,4-Oxadiazolen. Die zugrundeliegende Cycloaddition ermöglicht, unter Silbertriflat-Katalyse, die Umsetzung unterschiedlicher Silylnitronate und Nitrile.
Nikodemiak, Paul
core +1 more source
Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) [PDF]
, 2019 This review focuses on the use of oxadiazoles as translational readthrough-inducing drugs (TRIDs) to rescue the functional full-length protein expression in mendelian genetic diseases caused by nonsense mutations.
Campofelice A. +6 more
core +1 more source
Acta Crystallographica Section E, 2012 The title ionic compound, C16H36N+·C10H20B10N3O3−, consists of a tetrabutylammonium cation and a closo-decaborate cluster anion, which is bound to the substituted 2,3-dihydro-1,2,4-oxadiazole ring through a B—N bond [1.540 ...
Aleksey L. Mindich +4 more
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Halogen bond directionality translates tecton geometry into self-assembled architecture geometry [PDF]
, 2013 The structures of halogen-bonded infinite chains involving two diiodoperfluoroalkanes and a bent bis(pyrid-4′-yl)oxadiazole show that the geometry of the pyridyl pendant rings is translated into the angle between the formed halogen bonds.
Andrea Pace +7 more
core +1 more source
Cu(OH)x-clay catalyst promoted synthesis of 4,5-dihydro-1,2,4-oxadiazole at room temperature
Green Processing and Synthesis, 2018 An easy and efficient scheme is described and designed for the preparation of 4,5-dihydro-1,2,4-oxadiazole using recyclable Cu(OH)x-clay heterogeneous catalyst at room temperature.
Dar Bashir Ahmad +3 more
doaj +1 more source
Preparation of crosslinked 1,2,4-oxadiazole polymer [PDF]
, 1981 New crosslinked 1,2,4-oxadiazole elastomers were prepared by thermally condensing a monomer having the formula H2N(HON)C-R-Q, wherein Q is a triazine ring-forming group such as nitrile or amidine or a mixture of such group with amidoxime, or a mixture of
Kwong, H. +2 more
core +1 more source