Results 31 to 40 of about 1,134 (75)

5,5′-Thiobis(3-methoxy-4H-1,2,6-thiadiazin-4-one)

, 2019
The reaction of 3-chloro-5-methoxy-4H-1,2,6-thiadiazin-4-one (9) with Na2S·9H2O (0.5 equiv) in tetrahydrofuran (THF) at ca. 20 °C for 20 h gives 5,5′-thiobis(3-methoxy-4H-1,2,6-thiadiazin-4-one) (10) in a 44% yield as yellow needles. The
Panayiotis A. Koutentis, Andreas S. Kalogirou   +1 more
core   +1 more source

Inositol-1,2,6-trisphosphate in the treatment of burns

, 1998
Burns are often associated with severe pain, complicated wound healing and disfiguring and functionally limiting scar formation. The vast inflammatory response of the burn wound may produce local and systemic complications resulting in fluid imbalance ...
Tarnow, Peter 1963-
core   +1 more source

Synthesis of (R) and (S)-3-Chloro-5-(3-methylmorpholino)-4H-1,2,6-thiadiazin-4-ones

, 2020
Reaction of 3,5-dichloro-4H-1,2,6-thiadiazin-4-one with (R) and (S)-3-methylmorpholines (2 equiv), in THF, at ca. 20 °C gave (R) and (S)-3-chloro-5-(3-methylmorpholino)-4H-1,2,6-thiadiazin-4-ones in 95 and 97% yields, respectively.
Christopher R. M. Asquith, Panayiotis A. Koutentis, Andreas S. Kalogirou   +2 more
core   +1 more source

3,5-Bis[5-(thiazol-2-yl)thien-2-yl]-4H-1,2,6-thiadiazin-4-one

, 2019
Stille coupling of 3,5-bis(5-bromothien-2-yl)-4H-1,2,6-thiadiazin-4-one (10) with 2-(tri-n-butylstannyl)thiazole and Pd(Ph3P)2Cl2 in PhMe, at ca. 110 °C, for 2 h, gave 3,5-bis[5-(thiazol-2-yl)thien-2-yl]-4H-1,2,6-thiadiazin-4-one (9) in 81% yield.
Panayiotis A. Koutentis, Andreas S. Kalogirou   +1 more
core   +1 more source

Isothermal enthalpy relaxation of glassy 1,2,6-hexanetriol

, 1987
The isothermal enthalpy relaxation of glassy 1,2,6-hexanetriol has been measured at six temperatures. The relaxation time and the distribution parameters extracted from fits of the Williams-Watts relaxation function are compared with parameters obtained ...
Fransson, Åke,, Bäckström, Gunnar,
core   +1 more source

Synthesis and Selective Functionalization of Thiadiazine 1,1-Dioxides with Efficacy in a Model of Huntington's Disease. [PDF]

ACS Med Chem Lett, 2020
Terrab L, Rosenker CJ, Johnstone L, Ngo LK, Zhang L, Ware NF, Miller B, Topacio AZ, Sannino S, Brodsky JL, Wipf P.   +10 more
europepmc   +1 more source

A Novel Selective 11β-HSD1 Inhibitor, (E)-4-(2-(6-(2,6-Dichloro-4-(Trifluoromethyl)Phenyl)-4-Methyl-1,1-Dioxido-1,2,6-Thiadiazinan-2-yl)Acetamido)Adamantan-1-Carboxamide (KR-67607), Prevents BAC-Induced Dry Eye Syndrome. [PDF]

Int J Mol Sci, 2020
Na YJ, Choi KJ, Jung WH, Park SB, Kang S, Ahn JH, Kim KY.   +6 more
europepmc   +1 more source

Novel and selective inactivators of Triosephosphate isomerase with anti-trematode activity. [PDF]

Sci Rep, 2020
Ferraro F, Corvo I, Bergalli L, Ilarraz A, Cabrera M, Gil J, Susuki BM, Caffrey CR, Timson DJ, Robert X, Guillon C, Freire T, Álvarez G.   +12 more
europepmc   +1 more source

Palladium Catalyzed C–C Coupling Reactions of 3,5-Dichloro-4H-1,2,6-thiadiazin-4-one

, 2016
Palladium catalyzed Suzuki–Miyaura, Stille, and Sonogashira coupling reactions are reported for the electron-deficient heterocyclic scaffold 3,5-dichloro-4H-1,2,6-thiadiazin-4-one (1).
Heraklidia A. Ioannidou (1332144), Christos Kizas (2151226), Panayiotis A. Koutentis (1278807)   +2 more
core   +1 more source

Synthesis of 1,2,6-Thiadiazin 1,1-Dioxide Derivatives as Trypanocidal Agents

, 2000
It describes the synthesis of new 1,2,6-Thiadiazin 1,1-dioxide derivatives using condensation of the Knoevenagel type.
H. Cerecetto, C. Ochoa, R. Di Maio, S. Muelas, G. Seoane, A. Gómez-Barrio, A. Gómez-Barrio   +6 more
core   +1 more source