Results 21 to 30 of about 22,593 (123)

Dual‐Mode Thio‐MacMillan Organocatalysts: Stereoselective Diels–Alder Reactions or Sacrificial Self‐Cyclization to N‐Bridged Bicyclic Lactams

Chemistry – A European Journal, EarlyView.
The study of the Diels–Alder reaction of cinnamaldehyde and cyclopentadiene, catalyzed by chiral imidazolidine‐4‐thiones, led to the discovery of a highly regio‐ and stereoselective Michael‐addition and consecutive ring closure. Here, the imidazolidine‐4‐thione not only catalytically activates cinnamaldehyde but also participates as the nucleophile to ...
Marian S. R. Ebeling, Luca V. Parziale, Marc Sachsenhauser, Christoph J. B. Seifert, Nathalie J. Kurrle, Oliver Trapp   +5 more
wiley   +1 more source

Switchable Reactivities of Metalated Phosphasilenes Regulated by Reversible 1,2‐Metal Migration

Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.
We develop novel strategies for the facile synthesis of anionic phosphasilenes in the forms of both P‐metalation and Si‐metalation. The P‐metalated phosphasilene displays a pronounced π‐bond‐driven reactivity toward robust inert molecules, whereas the Si‐metalated analogue behaves as a silylene equivalent via a retro‐1,2‐silver migration.
Huaiyuan Zhu, Shicheng Dong, Xufang Liu, Xiyuan Li, Tobias Weng, Jun Zhu, Shigeyoshi Inoue   +6 more
wiley   +2 more sources

Synthesis and Evaluation of the First Generation of Glycosylated Nucleoside Analogues as Potential Inhibitors of the Base J Metabolism in Kinetoplastid Parasites

Chemistry – A European Journal, EarlyView.
Novel analogues of the kinetoplastid‐specific DNA base J unlock a new way to target parasite epigenetic regulation. Some compounds selectively inhibit Leishmania and Trypanosoma species without harming human cells, revealing a promising route toward innovative antiparasitic therapies.
Océane Monfret, Dan Liu, Manon Louis, Sihem Rebei, Dominique Urban, Yann Bourdreux, Elisabeth Mouray, Philippe Grellier, Gilles Doisneau, Dominique Guianvarc'h   +9 more
wiley   +1 more source

Cyclooctyne-based reagents for uncatalyzed click chemistry: A computational survey [PDF]

, 2009
With the goal of identifying alkyne-like reagents for use in click chemistry, but without Cu catalysts, we used B3LYP density function theory (DFT) to investigate the trends in activation barriers for the 1,3-dipolar cycloadditions of azides with various
Chenoweth, David, Chenoweth, Kimberly, Goddard, William A. III   +2 more
core   +1 more source

Influence of activated carbons on the kinetics and mechanisms of aromatic molecules ozonation [PDF]

, 2010
Companies have been looking for new methods for treating toxic or refractory wastewaters; which can mainly be used prior to or after or in connexion with biological treatment processes.This paper compares conventional ozone oxidation with activatedcarbon
Debellefontaine, Hubert, Manero, Marie-Hélène, Mathé, Stéphane, Merle, Tony, Pic, Jean-Stéphane   +4 more
core   +2 more sources

Silent Partners in the Mill: Unveiling the Role of Additives in Mechanochemical Synthesis

Chemistry – A European Journal, EarlyView.
Mechanochemistry offers a sustainable, solvent‐free alternative to traditional synthesis, often enhanced by additives in a process known as additive‐assisted grinding. This review discusses how various additives, including liquids, ionic solids, and advanced materials like ionic liquids and piezoelectric compounds, improve reaction efficiency ...
Johanna Breinsperger, Nika Podlesnik, Francesco Mele, Michael Schnürch   +3 more
wiley   +1 more source

B‐N Fused Anthracene as Functional Linker for π‐Extended Viologens: Near‐IR Emission and Electrochromism

Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.
We introduce π–extended viologens with B‐N fused dipyridylanthracene (BDPA) as conduit for delocalization. Quaternization of pyridyl‐substituted BDPA by methylation or Lewis pair formation with B(C6F5)3 produces strongly colored compounds that are emissive in the near‐IR.
Rajendra Prasad Nandi, Jingyao Zuo, Abhishek Shibu, Frieder Jäkle   +3 more
wiley   +2 more sources

Concerted [4 + 2] and Stepwise (2 + 2) Cycloadditions of Tetrafluoroethylene with Butadiene: DFT and DLPNO-UCCSD(T) Explorations. [PDF]

, 2020
Tetrafluoroethylene and butadiene form the 2 + 2 cycloadduct under kinetic control, but the Diels-Alder cycloadduct is formed under thermodynamic control. Borden and Getty showed that the preference for 2 + 2 cycloaddition is due to the necessity for syn-
Houk, KN, Liu, Peng, Mackey, Joel L, Pemberton, Ryan P, Svatunek, Dennis   +4 more
core  

Synthesis of Chromen[4,3-b]pyrrolidines by Intramolecular 1,3-Dipolar Cycloadditions of Azomethine Ylides: An Experimental and Computational Assessment of the Origin of Stereocontrol [PDF]

, 2015
Azomethine ylides, generated from imine-derived O-cinnamyl or O-crotonyl salicylaldeyde and α-amino acids, undergo intramolecular 1,3-dipolar cycloaddition, leading to chromene[4,3-b]pyrrolidines.
Arrieta, Ana, Barcellos, Julio C.F., Cossío Mora, Fernando Pedro, Cossío, Unai, Costa, Paulo R.R., Cózar Ruano, Abel de, Dias, Ayres G., Nájera, Carmen, Sansano, Jose M.   +8 more
core   +2 more sources

A Tandem Chemical Vapor Deposition Platform for the Solvent‐Free Synthesis of Polypeptide Architectures

Chemistry – A European Journal, EarlyView.
A solvent‐free, two‐step chemical vapor polymerization enables efficient, substrate‐independent synthesis of surface‐attached polypeptide films. Initiator deposition via CVD is followed by NCA ring‐opening polymerization. Characterization confirms film formation and functionalization, allowing precise micropatterning and bioactive surface design for ...
Domenic Kratzer, Martina Plank, Meike Koenig, Tahereh Mohammadi Hafshejani, Joerg Lahann   +4 more
wiley   +1 more source