Results 41 to 50 of about 16,669 (224)

Synthesis of Novel Spiro-Isoxazolidine Derivatives of 9α-Hydroxyparthenolide

Molbank
The 1,3-dipolar cycloaddition reaction was applied to 9α-hydroxyparthenolide, an important sesquiterpene component of Anvillea radiata that was extracted directly from plant material collected in Morocco.
Mohamed Zaki, Mohammed Loubidi, Sabine Berteina-Raboin   +2 more
doaj   +1 more source

Iridium-Catalyzed 1,3-Dipolar Cycloadditions [PDF]

, 2010
The authors thank financial support from Ministerio de Ciencia e Innovación (MICINN, Spain) and FEDER (Grant CTQ2009/10303BQU) and MULTICAT, Consolider Ingenio- 2010 (CSD2009-00050).
Carmona, Daniel, Oro, Luis A.
openaire   +2 more sources

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

Advanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch, Peter Goettig, Michael A. Nash, Juri Rappsilber, Nediljko Budisa   +4 more
wiley   +1 more source

Dimerization of propargyl and homopropargyl 6-azido-6-deoxy-glycosides upon 1,3-dipolar cycloaddition

Beilstein Journal of Organic Chemistry, 2008
Copper-catalyzed, thermal or microwave promoted 1,3-dipolar cycloaddition (Click Reaction) of 2-propynyl and 3-butynyl 2,3,4-tri-O-acetyl-6-azido-6-deoxy-glycopyranosides in the D-gluco, D-galacto and D-manno series afford the corresponding dimeric ...
Nikolas Pietrzik, Daniel Schmollinger, Thomas Ziegler   +2 more
doaj   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

Advanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen, Wei Zeng, Zherui Zhao, JiYu Zhao, Ziyan Huang, Zhuo Chen, Kui Zhou, Guanglong Ding, Su‐Ting Han, Ye Zhou   +9 more
wiley   +1 more source

Organocatalyzed Enantio- and Diastereoselective Domino [3+2]-Dipolar Cycloaddition: Synthesis of Chiral Pyrrorlo-thiazine-2-carbaldehydes and Dihydropyrrole-3-carbaldehydes

, 2023
1,3-Dipolar cycloaddition of azomethine ylide and dipolarophile is an efficient method to construct N, S heterocycles such as thiazoles, 1,4-thiazines, and their chiral polyhydro derivatives.
Venkata Surya Kumar , Choutipalli, Venkatesan , Subramanian, Govindasamy , Sekar, Solai, Pandidurai   +3 more
core   +1 more source

Synthesis of New bis 1- and 5-Substituted 1H-Tetrazoles via Huisgen-Type 1,3-Dipolar Cycloadditions

Proceedings, 2019
The synthesis and characterization of one symmetrical bis-1-substituted-1H-tetrazole (69%) via a Huisgen-type 1,3-dipolar cycloaddition, as well as, one symmetrical aza-linked bis-5-substituted-1H-tetrazole (57%) via a classic Huisgen 1,3-dipolar ...
Roberto E. Blanco-Carapia, Julio C. Flores-Reyes, Yizrell Medina-Martínez, Perla Islas-Jácome, Diego Pérez-Martínez, Leticia Lomas-Romero, Ilich A. Ibarra, Alejandro Islas-Jácome, Eduardo González-Zamora   +8 more
doaj   +1 more source

1,3-Dipolar cycloadditions of azomethine imines

Organic & Biomolecular Chemistry, 2015
Azomethine imines react with alkenes and alkynes to give pyrazolines, pyrazolidines, pyrazolopyridines, indazoloisoquinolines, pyrazolo[1,5-a]isoquinolines and pyrazolopyrazolones through regio-, stereo- and enantioselective 1,3-dipolar cycloadditions.
Nájera, Carmen, Sansano, Jose M., Yus, Miguel   +2 more
openaire   +4 more sources

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, EarlyView.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

1,3 dipolar cycloaddition of münchnones: Factors behind the regio-selectivity

, 2022
The 1,3 dipolar cycloaddition reactions of münchnones and alkenes provide an expedite synthetic way to substituted pyrroles, an exceedingly important structural motif in the pharmaceutical and material science fields of research.
Juan J., González Armesto, Luis A. , Montero-Cabrera, Marco, Martínez González, Meylin , Bocalandro   +3 more
core   +1 more source