Results 51 to 60 of about 23,273 (217)

Synthesis of Heterocylic Compounds of Biological Interest from Carbohydrate Derivatives

Molecules, 2000
The synthesis of some isoxazolic compounds from carbohydrate derivatives is described. These products are obtained by 1,3-dipolar cycloaddition reaction and their functionalization leads to derivatives with potential biological activities.
M. F. Martinez Esperón, M. L. Fascio, N. B. D’Accorso   +2 more
doaj   +1 more source

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

Advanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch, Peter Goettig, Michael A. Nash, Juri Rappsilber, Nediljko Budisa   +4 more
wiley   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

Advanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen, Wei Zeng, Zherui Zhao, JiYu Zhao, Ziyan Huang, Zhuo Chen, Kui Zhou, Guanglong Ding, Su‐Ting Han, Ye Zhou   +9 more
wiley   +1 more source

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, EarlyView.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

Chemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis, Kyriakos D. Nikopoulos, Ioannis N. Lykakis   +2 more
wiley   +1 more source

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, EarlyView.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

A Convenient, Safe, and Atom‐Economical Route to a Large Portfolio of Grubbs‐Type Catalysts for Olefin Metathesis via Four‐Coordinate Ruthenium Alkylidynes

Angewandte Chemie, Volume 138, Issue 16, 13 April 2026.
It may seem counterintuitive to first target a ruthenium alkylidyne when Grubbs‐type ruthenium carbene complexes are the actual goal. In the end, however, this tactic pays valuable dividends in terms of practicality, atom economy, flexibility as well as safety: the new route provides ready access to a large assortment of catalysts for alkene metathesis
Mingxu Cui, Alois Fürstner
wiley   +2 more sources

1,2‐Diazetidines − Structure, Synthesis, and Functionalization

European Journal of Organic Chemistry, EarlyView.
1,2‐Diazetidines are saturated four‐membered heterocycles featuring two adjacent nitrogen atoms. Despite recent advances in their synthesis and promising potential in medicinal chemistry, the chemistry of these cyclic hydrazines remains underexplored.
Stefan Roesner
wiley   +1 more source

Phase‐Transfer‐Catalyzed Interrupted Barton–Zard Reaction Between Electron‐Deficient Indoles and Benzophenone‐Derived Isocyanides

European Journal of Organic Chemistry, EarlyView.
A cascade reaction under phase‐transfer conditions between 3‐nitro indoles and isocyanomethylene dibenzenes affords the construction of pyrrolo[3,4‐b]indole cores. Control experiments provide insight into moderate product yields and clarify why the reaction is not amenable to asymmetric induction. A cascade reaction enabling the construction of pyrrolo[
Ana Mikleušević, Ines Bašić, Mateja Matišić, Josip Rešetar, Matija Gredičak   +4 more
wiley   +1 more source