Results 61 to 70 of about 16,682 (222)

Peptide Macrocyclization via Cu-catalyzed 1,3-Dipolar Cycloaddition of Azomethine Ylides [PDF]

Cyclic peptides are highly valued synthetic targets in organic and medicinal chemistry. The development of new synthetic methodologies for peptide macrocyclization, different from classical lactamization, is essential for the progress of the field ...
Francisco Javier, Adrio, Juan Carlos, Carretero, Inés, Alonso, Enrique, Gallent, Nuria, Rodriguez   +4 more
core   +1 more source

Intramolecular 1,3-dipolar cycloaddition of cyclo-1,3-diene-tethered nitrile oxides [PDF]

, 2020
-Intramolecular 1,3-dipolar cycloaddition of cyclo-1,3-diene-and -1,3,5-triene-tethered nitrile oxides gave tricyclic isoxazolines as a single stereoisomer in most cases.
Kumar Reddy, Chi-Fen Jou, N Ravi, Ming-Chang P Yeh, Wei-Tzou Yeh, Da-Yu Chiu   +5 more
core  

An Efficient Synthesis of Novel Dispirooxindole Derivatives via One-Pot Three-Component 1,3-Dipolar Cycloaddition Reactions

Molecules, 2012
A series of novel dispirooxindoles have been synthesized through three-component 1,3-dipolar cycloaddition of azomethine ylides generated in situ by the decarboxylative condensation of isatin and an α-amino acid with the dipolarophile 5-benzylidene-1,3 ...
Yucheng Wang, Juxian Wang, Hongtao Liu, Huiyuan Wang, Wei Lin, Lexing Xu, Zhibin Huang, Gang Chen, Qian Zhao, Daqing Shi   +9 more
doaj   +1 more source

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, Volume 65, Issue 31, 27 July 2026.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

(S)-(-)-Limonene Derivatives Containing (1H-1,2,3-Triazol-4-yl)methyl 4-Bromobenzoate

Molbank, 2011
The synthesis of (S)-(-)-limonene derivatives containing (1H-1,2,3-triazol-4-yl)methyl 4-bromobenzoate were obtained by epoxidation, azidolysis and Huisgen’s 1,3-dipolar cycloaddition.
Guillermo Valdomir, Danilo Davyt
doaj   +1 more source

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

Cristais líquidos termotrópicos calamíticos contendo o heterociclo [1,2,3]-triazol 1,4-dissubstituído [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em QuímicaA síntese e as propriedades térmicas de cinco séries homólogas de compostos calamíticos lineares e não lineares,
Santos, Deise Maria Pereira de Oliveira
core  

Microwave-Assisted Synthesis of Fluorescent Pyrido[2,3-b]indolizines from Alkylpyridinium Salts and Enaminones

Molecules, 2020
Pyridinium ylides are well recognized as dipoles for cycloaddition reactions. In its turn, the microwave-assisted interaction of N-(cyanomethyl)-2-alkylpyridinium salts with enaminones unexpectedly proceeds as a domino sequence of cycloisomerization and ...
Ekaterina A. Sokolova, Alexey A. Festa, Karthikeyan Subramani, Victor B. Rybakov, Alexey V. Varlamov, Leonid G. Voskressensky, Erik V. Van der Eycken   +6 more
doaj   +1 more source

Nuclear Quantum Effects on the Organic Bifurcation Reaction in Microsolvated Water Clusters: Ring‐Polymer Molecular Dynamics Calculations Using an Explicit Solvation Model

Journal of Computational Chemistry, Volume 47, Issue 19, 15 July 2026.
Ring‐polymer molecular dynamics in explicit water clusters shows that nuclear quantum effects steer an organic bifurcation reaction—enhancing the minor (4 + 2) channel and accelerating water‐mediated proton transfer—proving that accurate aqueous reaction dynamics require both explicit solvation and nuclear quantum effects. ABSTRACT Solvent environments
Shoto Nakagawa, Hayato Matsubuchi, Haruki Ota, Toshiyuki Takayanagi, Tatsuhiro Murakami   +4 more
wiley   +1 more source

CUCURBITURIL-INDUCED 1,3-DIPOLAR CYCLOADDITION. [PDF]

, 1986
CUCURBITURIL-INDUCED 1,3-DIPOLAR ...
MITA. ADHYA (7978196)
core