Results 31 to 40 of about 16,682 (222)

A Suitable Functionalization of Nitroindazoles with Triazolyl and Pyrazolyl Moieties via Cycloaddition Reactions

Molecules, 2019
The alkylation of a series of nitroindazole derivatives with 1,2-dibromoethane afforded the corresponding N-(2-bromoethyl)- and N-vinyl-nitro-1H-indazoles.
Mohammed Eddahmi, Nuno M. M. Moura, Latifa Bouissane, Ouafa Amiri, M. Amparo F. Faustino, José A. S. Cavaleiro, Ricardo F. Mendes, Filipe A. A. Paz, Maria G. P. M. S. Neves, El Mostapha Rakib   +9 more
doaj   +1 more source

Novel valdecoxib derivatives by ruthenium(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes – synthesis and COX-2 inhibition activity [PDF]

, 2018
By Ru(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes 3,4-diaryl-substituted isoxazoles are formed in one step, showing high inhibition potency for COX-2.
Roscales García, Silvia, Pietzsch, Jens, Kniess, Torsten, Holger Weiss, Daniel, Torsten Kniess, Köckerling, Martin, Martin Köckerling, Bechmann, Nicole, Daniel Holger Weiss, Nicole Bechmann, Silvia Roscales, Jens Pietzsch   +11 more
core   +1 more source

Iridium-Catalyzed 1,3-Dipolar Cycloadditions [PDF]

, 2010
1,3-Dipolar cycloaddition reactions (DCR) are atom-economic processes that permit the construction of heterocycles. Their enantioselective versions allow for the creation of up to four adjacent chiral centers in a concerted fashion. In particular, well-defined half-sandwich iridium (III) catalysts have been applied to the DCR between enals or ...
Daniel Carmona, Luis A. Oro
openaire   +1 more source

PHOSPHONATED ISOXAZOLIDINYL NUCLEOSIDES, A NEW CLASS OF MODIFIED NUCLEOSIDES [PDF]

Euromediterranean Biomedical Journal, 2014
This review offers an overview of the synthesis of phosphonated isoxazolidinyl nucleosides, a new class of interesting and potentially antiviral/antitumor agents.
Salvatore Giofrè
doaj   +1 more source

Synthesis of bis-spirocyclic derivatives of 3-azabicyclo[3.1.0]hexane via cyclopropene cycloadditions to the stable azomethine ylide derived from Ruhemann's purple

Beilstein Journal of Organic Chemistry, 2022
A reliable method for the synthesis of bis-spirocyclic derivatives of 3-azabicyclo[3.1.0]hexanes through the 1,3-dipolar cycloaddition (1,3-DC) reactions of cyclopropenes to the stable azomethine ylide – protonated form of Ruhemann's purple (PRP) has ...
Alexander S. Filatov, Olesya V. Khoroshilova, Anna G. Larina, Vitali M. Boitsov, Alexander V. Stepakov   +4 more
doaj   +1 more source

1,3-Dipolar Cycloaddition Reactions of trans-2-Methylene-1,3-dithiolane 1,3-Dioxide with Nitrones [PDF]

, 2016
1,3-Dipolar Cycloaddition Reactions of trans-2-Methylene-1,3-dithiolane 1,3-Dioxide with ...
Peter L. Spargo (3042906), Varinder K. Aggarwal (1363332), Richard S. Grainger (1335045), Harry Adams (1327698)   +3 more
core   +1 more source

Synthesis of Heterocylic Compounds of Biological Interest from Carbohydrate Derivatives

Molecules, 2000
The synthesis of some isoxazolic compounds from carbohydrate derivatives is described. These products are obtained by 1,3-dipolar cycloaddition reaction and their functionalization leads to derivatives with potential biological activities.
M. F. Martinez Esperón, M. L. Fascio, N. B. D’Accorso   +2 more
doaj   +1 more source

Synthesis of Novel Spiro-Isoxazolidine Derivatives of 9α-Hydroxyparthenolide

Molbank
The 1,3-dipolar cycloaddition reaction was applied to 9α-hydroxyparthenolide, an important sesquiterpene component of Anvillea radiata that was extracted directly from plant material collected in Morocco.
Mohamed Zaki, Mohammed Loubidi, Sabine Berteina-Raboin   +2 more
doaj   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

Advanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi, Felix Geng, Jan‐Noël Frenzke, Gregor Fuhrmann   +3 more
wiley   +1 more source

Antibody-Catalysis of a Bimolecular Asymmetric 1,3-Dipolar Cycloaddition Reaction [PDF]

, 2016
Antibody-Catalysis of a Bimolecular Asymmetric 1,3-Dipolar Cycloaddition ...
Yunfeng Hu (2255629), Paul Wentworth, (2668996), Jonathan D. Toker (2668999), K. N. Houk (1247004), Kim D. Janda (163029)   +4 more
core   +1 more source