Results 21 to 30 of about 23,273 (217)

Ultrasound-assisted one-pot three-component synthesis of new isoxazolines bearing sulfonamides and their evaluation against hematological malignancies

open access: yesUltrasonics Sonochemistry, 2021
In the present study, following a one-pot two-step protocol, we have synthesized novel sulfonamides-isoxazolines hybrids (3a-r) via a highly regioselective 1,3-dipolar cycloaddition. The present methodology capitalized on trichloroisocyanuric acid (TCCA)
Aicha Talha   +9 more
doaj   +1 more source

MODIFICATION OF NOVEL ISOXAZOLINES OF FULVENE DERIVATIVES WITH 1,3-DIPOLAR CYCLOADDITION REACTION

open access: yesJournal of the Turkish Chemical Society, Section A: Chemistry, 2018
In this work, 1,3-Dipolar cycloaddition reactions were studied to synthesize fulvene derivatives containing isoxazoline groups in good yields. 1,3-Dipolar cycloaddition reactions are among the most useful strategies for the preparation of organic ...
Omer Gunkara
doaj   +1 more source

Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition [PDF]

open access: yes, 2011
A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the ...
Engels, Joachim W.   +2 more
core   +2 more sources

Highly Efficient Construction of Sugar-Fused Spirochromanono Pyrrolidines/Pyrrolizidines/Thiolizidines via 1,3-Dipolar Cycloaddition of Azomethine Ylides

open access: yesSynOpen, 2017
A variety of sugar-fused chromanono pyrrolidines/pyrrolizidines/thiolizidines have been synthesized by intermolecular 1,3-dipolar cycloaddition reaction of azomethine ylides (generated from glucose aldehyde and different secondary amino acids) with ...
Sirisha Nallamala   +2 more
doaj   +1 more source

Discovery of new mutually orthogonal bioorthogonal cycloaddition pairs through computational screening. [PDF]

open access: yes, 2015
Density functional theory (DFT) calculations and experiments in tandem led to discoveries of new reactivities and selectivities involving bioorthogonal sydnone cycloadditions.
Houk, KN   +3 more
core   +1 more source

Theoretical analysis of the mechanism and regioselectivity of the 1, 3-dipolar cycloaddition of E-3-(dimethylamino)-1-(10H-phenothiazin-2-yl)prop-2-en-1-one with some nitrilimines using DFT and the distortion/interaction model

open access: yesActa Chimica Slovenica, 2015
The regiochemistry of 1,3-dipolar cycloaddition reactions of E-3-(dimethylamino)-1-(10H-phenothiazin-2-yl) prop-2-en-1-one with some nitrilimines were investigated using density functional theory (DFT) -based reactivity indexes, activation energy ...
Farid Moeinpour, Amir Khojastehnezhad
doaj   +1 more source

Dynamic Catalytic Highly Enantioselective 1,3‐Dipolar Cycloadditions [PDF]

open access: yesAngewandte Chemie International Edition, 2021
AbstractIn dynamic covalent chemistry, reactions follow a thermodynamically controlled pathway through equilibria. Reversible covalent‐bond formation and breaking in a dynamic process enables the interconversion of products formed under kinetic control to thermodynamically more stable isomers.
Yildirim, O   +5 more
openaire   +7 more sources

Intramolecular Azide to Alkene Cycloadditions for the Construction of Pyrrolobenzodiazepines and Azetidino-Benzodiazepines [PDF]

open access: yes, 2014
The coupling of proline- and azetidinone-substituted alkenes to 2-azidobenzoic and 2-azidobenzenesulfonic acid gives precursors that undergo intramolecular azide to alkene 1,3-dipolar cycloadditions to give imine-, triazoline- or aziridine-containing ...
Antonow   +9 more
core   +2 more sources

Nitrile Oxide, Alkenes, Dipolar Cycloaddition, Isomerization and Metathesis Involved in the Syntheses of 2-Isoxazolines

open access: yesMolecules, 2023
The involvement of 1,3-dipolar cycloaddition (1,3-DP), double bond migration, metathesis, and nitrile oxide (including in situ-generated nitrile oxide) as dipoles, together with the C=C bond containing dipolarophiles, in the syntheses of 2-isoxazolines ...
Stanisław Krompiec   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy