Results 21 to 30 of about 23,273 (217)
The Huisgen Reaction: Milestones of the 1,3-Dipolar Cycloaddition. [PDF]
Breugst M, Reissig HU.
europepmc +2 more sources
In the present study, following a one-pot two-step protocol, we have synthesized novel sulfonamides-isoxazolines hybrids (3a-r) via a highly regioselective 1,3-dipolar cycloaddition. The present methodology capitalized on trichloroisocyanuric acid (TCCA)
Aicha Talha +9 more
doaj +1 more source
MODIFICATION OF NOVEL ISOXAZOLINES OF FULVENE DERIVATIVES WITH 1,3-DIPOLAR CYCLOADDITION REACTION
In this work, 1,3-Dipolar cycloaddition reactions were studied to synthesize fulvene derivatives containing isoxazoline groups in good yields. 1,3-Dipolar cycloaddition reactions are among the most useful strategies for the preparation of organic ...
Omer Gunkara
doaj +1 more source
Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition [PDF]
A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the ...
Engels, Joachim W. +2 more
core +2 more sources
A variety of sugar-fused chromanono pyrrolidines/pyrrolizidines/thiolizidines have been synthesized by intermolecular 1,3-dipolar cycloaddition reaction of azomethine ylides (generated from glucose aldehyde and different secondary amino acids) with ...
Sirisha Nallamala +2 more
doaj +1 more source
Discovery of new mutually orthogonal bioorthogonal cycloaddition pairs through computational screening. [PDF]
Density functional theory (DFT) calculations and experiments in tandem led to discoveries of new reactivities and selectivities involving bioorthogonal sydnone cycloadditions.
Houk, KN +3 more
core +1 more source
The regiochemistry of 1,3-dipolar cycloaddition reactions of E-3-(dimethylamino)-1-(10H-phenothiazin-2-yl) prop-2-en-1-one with some nitrilimines were investigated using density functional theory (DFT) -based reactivity indexes, activation energy ...
Farid Moeinpour, Amir Khojastehnezhad
doaj +1 more source
Dynamic Catalytic Highly Enantioselective 1,3‐Dipolar Cycloadditions [PDF]
AbstractIn dynamic covalent chemistry, reactions follow a thermodynamically controlled pathway through equilibria. Reversible covalent‐bond formation and breaking in a dynamic process enables the interconversion of products formed under kinetic control to thermodynamically more stable isomers.
Yildirim, O +5 more
openaire +7 more sources
Intramolecular Azide to Alkene Cycloadditions for the Construction of Pyrrolobenzodiazepines and Azetidino-Benzodiazepines [PDF]
The coupling of proline- and azetidinone-substituted alkenes to 2-azidobenzoic and 2-azidobenzenesulfonic acid gives precursors that undergo intramolecular azide to alkene 1,3-dipolar cycloadditions to give imine-, triazoline- or aziridine-containing ...
Antonow +9 more
core +2 more sources
The involvement of 1,3-dipolar cycloaddition (1,3-DP), double bond migration, metathesis, and nitrile oxide (including in situ-generated nitrile oxide) as dipoles, together with the C=C bond containing dipolarophiles, in the syntheses of 2-isoxazolines ...
Stanisław Krompiec +7 more
doaj +1 more source

