Moranoline (1-Deoxynojirimycin) Fermentation and Its Improvement
Agricultural and Biological Chemistry, 1985 Moranoline (1-deoxynojirimycin) is a strong α-glucosidase inhibitor. A rapid screening method for isolation of moranoline-producing Streptomyces (oblate agar plate method) was developed. A glucoamylase inhibitor was isolated from the culture filtrate of Streptomyces lavendulae GC-148, a mutant strain obtained from Streptomyces lavendulae MB-733, a soil
Yohji EZURE +3 more
openaire +2 more sources
Mulberry extract to modULate Blood glucosE Responses in noRmoglYcaemic adults (MULBERRY): study protocol for a randomized controlled trial [PDF]
, 2015 Background: worldwide sugar consumption has tripled during the last fifty years. High sugar intake is associated with weight gain and increased incidence of diabetes and has been linked with increased cardiovascular mortality.
Byrne, C. +7 more
core +1 more source
Native proteins in organic chemistry. Recent achievements in the use of non hydrolytic enzymes for the synthesis of pharmaceuticals [PDF]
, 2016 Financial support by the Spanish Ministerio de Economia y Competitividad (MINECO) through the CTQ-2013-44153-P project is grateful acknowledged. M.L.-I.
Gotor Fernández, Vicente +2 more
core +2 more sources
1-Deoxynojirimycin Derivatives from the Marine Sponge Lendenfeldia chondrodes [PDF]
The Journal of Antibiotics, 2006 Two 1-deoxynojirimycin derivatives, 1-deoxynojirimycin-6-phosphate (1) and N-methyl-1-deoxynojirimycin-6-phosphate (2) were isolated from an aqueous extract of Micronesian marine sponge Lendenfeldia chondrodes for the first time as natural products. Structures of these compounds were assigned on the basis of their spectral data and chemical degradation.
Ryuichi, Sakai, Hisao, Kamiya
openaire +2 more sources
Iminosugar inhibitors of carbohydrate-active enzymes that underpin cereal grain germination and endosperm metabolism [PDF]
, 2016 Starch is a major energy store in plants. It provides most of the calories in the human diet and, as a bulk commodity, it is used across broad industry sectors.
Alison M. Smith +57 more
core +2 more sources
Acta Chimica Slovenica, 2020 A series of N-alkylated deoxynojirimycin (DNJ) derivatives connected to a terminal tertiary amine at the alkyl chains of various lengths were prepared.
Lin Wang, Zhijie Fang
doaj +1 more source
Nutrition & Metabolism, 2021 Background There are many benefits of maintaining healthy blood glucose levels, and studies have shown that lifestyle changes such as changes to diet can successfully restore normoglycaemia in participants with dysglycaemia.
Pariyarath Sangeetha Thondre +3 more
doaj +1 more source
Effect of a novel nutraceutical combination on serum lipoprotein functional profile and circulating PCSK9 [PDF]
, 2017 BACKGROUND: A beneficial effect on cardiovascular risk may be obtained by improving lipid-related serum lipoprotein functions such as high-density lipoproteins (HDLs) cholesterol efflux capacity (CEC) and serum cholesterol loading capacity (CLC) and by ...
Adorni, Maria Pia +7 more
core +3 more sources
Quantitative determination of 1-deoxynojirimycin in 146 varieties of mulberry fruit
International Journal of Food Properties, 2021 1-deoxynojirimycin (DNJ) has attracted much attention due to its high biological activity, which have favorable anti-diabetic, anti-tumor, and anti-virus effects.
Zhenjiang Wang +5 more
doaj +1 more source
Reassessment of Acarbose as a Transition State Analogue Inhibitor of Cyclodextrin Glycosyltransferase [PDF]
, 1998 The binding of several different active site mutants of Bacillus circulans cyclodextrin glycosyltransferase to the inhibitor acarbose has been investigated through measurement of Ki values.
Dijkstra, Bauke W., +5 more
core +2 more sources