Enhancing 10-HDA production of Escherichia coli by heterologous expression of MexHID transporter proteins [PDF]
10-Hydroxy-2-decenoic acid (10-HDA) is a medium-chain α,β-unsaturated carboxylic acid that exists in royal jelly with terminal hydroxylation. It has a broad market value because of its antibacterial, anti-inflammatory, anti-tumor, anti-radiation, and ...
Ziting Xu +11 more
doaj +3 more sources
Antitumor Effects and the Potential Mechanism of 10-HDA against SU-DHL-2 Cells [PDF]
10-hydroxy-2-decenoic acid (10-HDA), which is a unique bioactive fatty acid of royal jelly synthesized by nurse bees for larvae and adult queen bees, is recognized for its dual utility in medicinal and nutritional applications.
Yuanyuan Tian +4 more
doaj +4 more sources
10-HDA, A Major Fatty Acid of Royal Jelly, Exhibits pH Dependent Growth-Inhibitory Activity Against Different Strains of Paenibacillus larvae [PDF]
Paenibacillus larvae (P. larvae) is a bacterial pathogen causing American foulbrood (AFB), the most serious disease of honeybee larvae. The food of young larvae could play an important role in the resistance of larvae against AFB.
Mária Šedivá +5 more
doaj +5 more sources
Dissecting the Molecular Mechanism of 10-HDA Biosynthesis: Role of Acyl-CoA Delta(11) Desaturase and Transcriptional Regulators in Honeybee Mandibular Glands [PDF]
10-Hydroxy-2-decenoic acid (10-HDA), a major fatty acid (FA) component of royal jelly, is synthesized in the mandibular glands (MGs) of worker honeybees.
Yunchang Li +3 more
doaj +3 more sources
Aplicação da CLAE para determinação do ácido 10-Hidróxi-2-decenóico (10-HDA) em geléia real pura e adicionada a mel brasileiro HPLC aplication for 10-HDA determination in pure royal jelly and honey with royal jelly [PDF]
The aim of this paper was to determine the 10-HDA in pure royal jelly and products containing royal jelly, using HPLC methodology. 10-HDA is the natural indicator of the presence of royal jelly in products and also gives the authenticity of pure royal ...
Shinnosuke Koshio +1 more
doaj +5 more sources
Microencapsulated and Fresh Royal Jelly: Monitoring 10-HDA Content, Antibacterial and Antifungal Activity at Different Storage Periods [PDF]
Royal Jelly (RJ) is a unique functional food having rich nutrient composition. Due to its extremely sensitive and perishable nature, the cold chain is inevitable to maintain the biological properties of RJ.
Neslihan Ulubayram, Aycan Yigit Cinar
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Preparation of Royal Jelly Effervescent Tablets and Determination of 10-HDA Dissolution
Objective: To solve the problem of low dissolution rate of 10-hydroxy-2-decenoic acid (10-HDA) in royal jelly effervescent tablets. Methods: The disintegration time and gas production were used as evaluation indexes.
Wen SHEN +3 more
doaj +2 more sources
10-HDA Induces ROS-Mediated Apoptosis in A549 Human Lung Cancer Cells by Regulating the MAPK, STAT3, NF-κB, and TGF-β1 Signaling Pathways. [PDF]
10‐Hydroxy‐2‐decenoic acid (10‐HDA), also known as royal jelly acid, has a variety of physiological functions, and recent studies have shown that it also has anticancer effects. However, its anticancer mechanisms have not been clearly defined. In this study, we investigated the underlying mechanisms of 10‐HDA in A549 human lung cancer cells.
Lin XM +10 more
europepmc +4 more sources
Morphogenetic markers of honey bees producing royal jelly with a high content of 10-HDA
The article provides the results of 2016-2018 study of morphogenetic markers in honey bees producing royal jelly with different content of 10-hydroxy-2-decenoic acid (10-HDA).
A. Z. Brandorf, M. M. Ivoilova
doaj +3 more sources
BackgroundAcute cadmium (Cd) exposure can cause damage to multiple tissues, with the kidney being the primary target organ. The development of Cd-induced acute kidney injury involves complex mechanisms, in which autophagy and oxidative stress play ...
Linwei LI +5 more
doaj +2 more sources

