The Synthesis, Antimicrobial Activity, and Molecular Docking of New 1, 2, 4-Triazole, 1, 2, 4-Triazepine, Quinoline, and Pyrimidine Scaffolds Condensed to Naturally Occurring Furochromones [PDF]
Pharmaceuticals, 2022 This study aims to synthesize a new series of furochromone derivatives, evaluate their antimicrobial properties, and improve the permeability of potent compounds to inhibit different types of bacteria and fungi.
Ameen Ali Abu-Hashem, Sami A. Al-Hussain
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Effects of 1, 2, 4-Triazole Additive on PEM Fuel Cell Conditioning. [PDF]
Membranes (Basel), 2020 Melt processing is one of the essential technologies for the mass production of polymer electrolyte membranes (PEM) at low cost. Azoles have been widely used in PEM to improve their conductivity at a relatively low humidity and recently as bifunctional additives in a melt blowing processing for PEM mass production.
Zhao N +4 more
europepmc +6 more sources
Synthesis and cytotoxic activity evaluation of some new 1, 3, 4-oxadiazole, 1, 3, 4-thiadiazole and 1, 2, 4- triazole derivatives attached to phthalimide [PDF]
Research in Pharmaceutical Sciences, 2021 Background and purpose: In the last few decades, nitrogen-rich heterocyclic compounds such as 1, 3, 4-thiadiazoles, 1, 2, 4-triazoles and 1, 3, 4-oxadiazoles have received considerable attention because of their notable biological properties, especially ...
Farshid Hassanzadeh +3 more
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Syntheses of 1, 2, 4 Triazole Derivatives and their Biological Activity [PDF]
E-Journal of Chemistry, 2008 Cyclisation of [4-(4-oxo-2-phenyl-4H-quinazolin-3-yl)-phenoxy]-acetic acid-N'-(substituted phenyl)-thiosemicarbazides with sodium metal in 99.0 % ethanol gave 3-[4-(4-substituted phenyl-5-thioxo-4,5-dihydro-1H-1,2,4 triazol-3-ylmethoxy)- phenyl]-2-phenyl-
Freddy H. Havaldar, Abhay R. Patil
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Synthesis of 1, 2, 4- Triazole Derivatives And Their Biological Activity Study
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017 This study includes the synthesis of new derivatives of 1, 2, 4- Triazole which are contain Schiff bases derived from 1, 4, 5, 6- tetrahydropyrimidine.
E. M. Hussain
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Synthesis, docking study, and structure activity relationship of novel anti-tumor 1, 2, 4 triazole derivatives incorporating 2-(2, 3- dimethyl aminobenzoic acid) moiety [PDF]
Pharmacia, 2022 A series of 1,2,4 triazole derivatives (H7-12) have been synthesized by reacting an excess of hydrazine hydrate with carbothioamide derivatives (H1-6).
Hiba Alsaad +3 more
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Novel 1, 2, 4‐Triazoles as Antifungal Agents
BioMed Research International, 2022 The development of innovative antifungal agents is essential. Some fungicidal agents are no longer effective due to resistance development, various side effects, and high toxicity. Therefore, the synthesis and development of some new antifungal agents are necessary. 1,2,4‐Triazole is one of the most essential pharmacophore systems between five‐membered
Zahra Kazeminejad +5 more
openaire +3 more sources
An in silico investigation of 1,2,4-triazole derivatives as potential antioxidant agents using molecular docking, MD simulations, MM-PBSA free energy calculations and ADME predictions [PDF]
Pharmacia, 2023 In this study, we’ve performed computable studies of previously synthesized 1,2,4-triazole derivatives by virtual screening due to antioxidant activity. Six enzymes responsible for regulating oxidative stress were selected as key targets. One hundred and
Yevhen Karpun +9 more
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Synthesis of 2-(3-chloro-4-nitro-1-benzothien-2-yl)-1,3,4-oxadiazole-1,3,4-thiadiazole and 5-(3-chloro-4-nitro-1-benzothien-2-yl)-4H-1,2,4-triazole-3-thiol [PDF]
مجلة التربية والعلم, 2010 In this paper the synthesis of some substituted 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole is reported. 3-chloro-4-nitro-2-chloro carbonyl benzo [b] thiophene(1) was synthesized from 2-nitrocinnamic acid by its reaction with thionyl chloride ...
Khalid M. Daoud +2 more
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Analysis of biological properties of 1,2,4-triazole-containing compounds (literature review)
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2022 In the latest conditions of development and formation of the pharmaceutical industry, the introduction of new synthetic medicines requires continuous monitoring of the quality and safety of their use.
A. V. Khilkovets, V. V. Parchenko
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