Syntheses of 1, 2, 4 Triazole Derivatives and their Biological Activity [PDF]
E-Journal of Chemistry, 2008 Cyclisation of [4-(4-oxo-2-phenyl-4H-quinazolin-3-yl)-phenoxy]-acetic acid-N'-(substituted phenyl)-thiosemicarbazides with sodium metal in 99.0 % ethanol gave 3-[4-(4-substituted phenyl-5-thioxo-4,5-dihydro-1H-1,2,4 triazol-3-ylmethoxy)- phenyl]-2-phenyl-
Freddy H. Havaldar, Abhay R. Patil
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Effects of 1, 2, 4-Triazole Additive on PEM Fuel Cell Conditioning [PDF]
Membranes, 2020 Melt processing is one of the essential technologies for the mass production of polymer electrolyte membranes (PEM) at low cost. Azoles have been widely used in PEM to improve their conductivity at a relatively low humidity and recently as bifunctional additives in a melt blowing processing for PEM mass production.
Zhao, Nana +4 more
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The Synthesis, Antimicrobial Activity, and Molecular Docking of New 1, 2, 4-Triazole, 1, 2, 4-Triazepine, Quinoline, and Pyrimidine Scaffolds Condensed to Naturally Occurring Furochromones [PDF]
Pharmaceuticals, 2022 This study aims to synthesize a new series of furochromone derivatives, evaluate their antimicrobial properties, and improve the permeability of potent compounds to inhibit different types of bacteria and fungi.
Ameen Ali Abu-Hashem, Sami A. Al-Hussain
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Syntheses, Characterization and Biological Activity of Some 1, 2, 4-Triazole Derivatives [PDF]
Journal of Chemistry, 2009 Syntheses of a series of 3‐alkyl‐4‐ amino‐5‐ cyanomethyl‐4H‐1, 2, 4‐triazoles with active methylene groups are described. The newly synthesized compounds were characterized by spectral and elemental analyses. Some compounds were screened for their antibacterial activity against S. aureus, E. coli, B. subtilis and P. aeruginosa.
R. J. Singh, Dharmendra Kumar Singh
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Comparative Study of Goitrogenic Actions of 3-Substituted 1, 2, 4-Triazoles in Rats.
Journal of Veterinary Medical Science, 1994 Antithyroid actions of 3-amino-1, 2, 4-triazole (ATZ), 3-mercapto-1, 2, 4-triazole (MTZ) and 3-nitro-1, 2, 4-triazole (NTZ), which are substituents on the 3-position of 1, 2, 4-triazole (TZ), and those of the parental compound, were compared in rats. After administration of either ATZ, MTZ, or NTZ, the thyroids of rats were enlarged with decreasing of ...
Masaya Takaoka +6 more
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Analgesic activity of the salts of 2-(5-(adamantane-1-yl)-4-R-1,2,4-triazole-3-ylthio)acetic acid
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016 Despite the varied approaches to the pain syndrome therapy with the changes and improvements of evolutionary medicine’s development and the drugs which are used to treat pain there are still considerable difficulties in solving this problem. Aim.
V. M. Odintsova
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Synthesis, docking study, and structure activity relationship of novel anti-tumor 1, 2, 4 triazole derivatives incorporating 2-(2, 3- dimethyl aminobenzoic acid) moiety [PDF]
Pharmacia, 2022 A series of 1,2,4 triazole derivatives (H7-12) have been synthesized by reacting an excess of hydrazine hydrate with carbothioamide derivatives (H1-6).
Hiba Alsaad +3 more
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Design, synthesis and evaluation of 1, 2, 4-triazole derivatives as antifungal. [PDF]
Journal of Current Pharma Research, 2012 Prafulla B. Choudhari +4 more
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Novel 1, 2, 4‐Triazoles as Antifungal Agents
BioMed Research International, 2022 The development of innovative antifungal agents is essential. Some fungicidal agents are no longer effective due to resistance development, various side effects, and high toxicity. Therefore, the synthesis and development of some new antifungal agents are necessary. 1,2,4‐Triazole is one of the most essential pharmacophore systems between five‐membered
Zahra Kazeminejad +5 more
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An in silico investigation of 1,2,4-triazole derivatives as potential antioxidant agents using molecular docking, MD simulations, MM-PBSA free energy calculations and ADME predictions [PDF]
Pharmacia, 2023 In this study, we’ve performed computable studies of previously synthesized 1,2,4-triazole derivatives by virtual screening due to antioxidant activity. Six enzymes responsible for regulating oxidative stress were selected as key targets. One hundred and
Yevhen Karpun +9 more
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