Results 31 to 40 of about 43,455 (160)

Regarding antihypertensive tablets standardization

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
Hypertension is one of the most important problems of medicine related to its prevalence, late diagnosis and inefficient treatment. Antihypertensive treatment is the most effective way to prevent cardiovascular complications and reduce mortality.
N. V. Parnyuk
doaj   +1 more source

Synthesis and properties of S-alkyl 4-amino-5-(5-(3-fluorophenyl)-pyrazol-3-yl)-1,2,4-triazole-3-thiol derivatives

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2023
An important direction of modern pharmaceutical science is the creation of promising biologically active compounds, which in the hands of scientists can be transformed into effective medicinal products. Heterocyclic compounds are the undisputed leader in
S. O. Fedotov, A. S. Hotsulia
doaj   +1 more source

Regioselectivity in the Thermal Rearrangement of Unsymmetrical 4-Methyl-4H-1,2,4-triazoles to 1-Methyl-1H-1,2,4-triazoles

open access: yesMolecules, 2001
The rearrangement of 4-methyl-3,5-diaryl-4H-1,2,4-triazoles to the corresponding 1-methyl-3,5-diaryl-1H-1,2,4-triazoles showed regioselectivity comparable to that observed for the alkylation of 3,5-diaryl-1H-1,2,4-triazoles.
Per H.J. Carlsen, Odd R. Gautun
doaj   +1 more source

Study of acute toxicity of new thiophene-containing derivatives of 1,2,4-triazole

open access: yesZaporožskij Medicinskij Žurnal, 2023
Acute toxicity studies are an integral part of preclinical studies of any new biologically active compound. It should be noted that it is this stage of research that is crucial regarding the possibility of further use of a pharmacologically active ...
A. V. Khilkovets, I. M. Bilai
doaj   +1 more source

Anticonvulsant activity 2-((5-(3-(4-fluorophenyl)-4-R2-1,2,4-triazole-3-yl)-thio)-1-arylethanone

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
The aim of work is to study of the anticonvulsant activity of 2-((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazole-3-yl)thio)-1-aryletanones, the establishment of some laws between the structure of compounds and their activity. Materials and methods.
O. A. Bihdan
doaj   +1 more source

1-(3-Bromopropyl)-4-(2-pyridyl)-1H-1,2,3-triazole

open access: yesActa Crystallographica Section E, 2009
In the structure of the title compound, C10H11BrN4, the plane of the substituted 1,2,3-triazole ring is tilted by 14.84 (10)° with respect to the mean plane of the pyridine ring.
Lyall R. Hanton   +2 more
doaj   +1 more source

Synthesis and structure of salts of 2-(((3-mercapto-5-methyl-4H-1,2,4-triazole-4-yl)imino)methyl)benzoic acid

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
Modern pharmacy and medicine can offer a substantial number of highly effective synthetic medicines. A great portion of these medicines falls into the group of 1,2,4-triazole derivatives.
T. V. Hlazunova
doaj   +1 more source

Experimental and DFT Investigation on the Corrosion Inhibition of Mild Steel by 1, 2, 3- triazole Regioisomers in 1M hydrochloric Acid Solution

open access: yesInternational Journal of Electrochemical Science, 2019
The inhibition effect of new isomers of the triazole derivative family, namely 1-[(4-ethyl-2-phenyl-4, 5- dihydro-1, 3-oxazol-4-yl)methyl]-4-phenyl-1H-1, 2, 3-triazole (Ph4) and 1-[(4-ethyl-2-phenyl-4, 5- dihydro-1, 3-oxazol-4-yl)methyl]-5-phenyl-1H-1, 2,
H. Rahmani   +9 more
doaj   +1 more source

Synthesis of Some Heterocyclic Compounds derived from 2-mercapto pyrimidine

open access: yesمجلة بغداد للعلوم, 2010
In this work 2-hydrazino pyrimidine (1) was prepared from 2-mercapto pyrimidine with hydrazine hydrate. Treatment of (1) with active methylene compounds gave 2-(3,5-dimethyl -1 H – Pyrazole-1-yl) pyrimidine , whereas the reaction of (1) with ...
Baghdad Science Journal
doaj   +1 more source

Physical-chemical properties of 2-((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazol-3-il)tio)-1-arylethanons and their reduced systems

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
The aim of work is the investigation of properties of 2-((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazol-3-yl)thio)-1-arylethanones and 2((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazol-3-yl)thio)-1-arylethanols using modern physical-chemical methods.Materials and ...
O. A. Bihdan
doaj   +1 more source

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