Results 41 to 50 of about 43,455 (160)

Synthesis, physic and chemical properties of 2-(4-R-5-(thiophene-2-ylmethyl)-4h-1,2,4-triazole-3-ylthio)acetate acids and their salts

Фармацевтичний журнал, 2018
Derivatives of 1,2,4-triazole are inherent in various types of biological activity. They can be used as pesticide and medicinal drugs (anticonvulsants, analgetics, antitumor and antibacterial).
O. A. Suhak, О. I. Panasenko, Ye. G. Knysh   +2 more
doaj   +1 more source

QSAR prediction of toxicity for a new 1,2,4-triazole derivatives with 2-bromo-5-methoxyphenyl fragment

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
New derivatives of 1,2,4-triazole are promising research targets due to their unique biological properties, including antimicrobial, antifungal, antitumor, and antioxidant activities.
M. P. Skoryi, R. O. Shcherbyna
doaj   +1 more source

Study acute toxicity of 4-(R-amino)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol in vivo

Фармацевтичний журнал, 2018
Typically, the system is already known are used as the core for a new substance, which have already proved themselves as potential drugs. So one of these is 1,2,4-triazole ring.
A. A. Safonov
doaj   +1 more source

Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives

Molecules, 2009
New imidazole ring derivatives comprising 1,3-oxazoline, Schiff's bases, thiadiazole, oxadiazole and 1,2,4-triazole moieties are reported. 3-Aminobiimidazol-4-one compounds 7a-c were synthesized by the reaction of compounds 6a-c with hydrazine hydrate ...
Abdul Jabar Kh. Atia
doaj   +1 more source

Antimicrobial and antifungal activity of new 4-(5-((5-(alkylthio)-4-R-4H-1,2,4-triazole-3-yl)thio)-1H-1,2,4-triazole-3-yl)pyridines

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
The resistance of such strains as Staphylococcus aureus, Escherichia coli extends to many antimicrobial drugs. This problem can be solved by searching for new drugs with high bactericidal and antifungal action.
Ye. O. Karpun, N. M. Polishchuk
doaj   +1 more source

Current research trends of 1,2,4-triazole derivatives biological activity (literature review)

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
derivatives 1,2,4-triazole, biological activity,
I. M. Bilai , V. I. Dariy, A. V. Khilkovets, A. I. Bilai   +3 more
doaj   +1 more source

3D QSAR study on substituted 1, 2, 4 triazole derivatives as anticancer agents by kNN MFA approach. [PDF]

Saudi Pharm J, 2023
Desai SP, Mohite SK, Alobid S, Saralaya MG, Patil AS, Das K, Almadani ME, Arif Hussain S, Hussain Alamer B, Abdulrahman Jibreel E, Ibrahim Almoteer A, Mohammed Basheeruddin Asdaq S.   +11 more
europepmc   +1 more source

Synthesis of 3,5-di-(4-pyridyl)-1H-1,2,4-triazole

Molbank, 2008
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Guang Yang, Li-Li Liu
doaj   +1 more source

The synthesis and highly effective antibacterial properties of Cu-3, 5-dimethy l-1, 2, 4-triazole metal organic frameworks. [PDF]

Front Chem, 2023
Xu X, Ding M, Liu K, Lv F, Miao Y, Liu Y, Gong Y, Huo Y, Li H.   +8 more
europepmc   +1 more source

An in vivo evaluation of anti-inflammatory, analgesic and anti-pyretic activities of newly synthesized 1, 2, 4 Triazole derivatives. [PDF]

BMC Complement Med Ther, 2021
Azim T, Wasim M, Akhtar MS, Akram I.
europepmc   +1 more source