Selective proliferation of intestinal Barnesiella under fucosyllactose supplementation in mice [PDF]
, 2014 The oligosaccharides 2-fucosyllactose and 3-fucosyllactose are major constituents of human breast milk but are not found in mouse milk. Milk oligosaccharides have a prebiotic action, thus affecting the colonisation of the infant intestine by microbiota ...
Hennet, Thierry +6 more
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Foods, 2023 Using 2′-fucosyllactose (2′-FL) as the sole carbon source can be an efficient way to screen bifidobacteria with superior probiotic capabilities since 2′-FL is a key element in promoting the growth of intestinal bifidobacteria in newborns.
Gongsheng Zhang +8 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2020 Recombinant whole-cell biocatalysts are widely used for biotransformation of valuable products. However, some key enzymes involved in biotransformation processes are unstable and cannot be easily expressed in the functional form.
Yunjeong Park +15 more
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Novel α-L-Fucosidases from a Soil Metagenome for Production of Fucosylated Human Milk Oligosaccharides. [PDF]
PLoS ONE, 2016 This paper describes the discovery of novel α-L-fucosidases and evaluation of their potential to catalyse the transglycosylation reaction leading to production of fucosylated human milk oligosaccharides.
Mateusz Lezyk +5 more
doaj +1 more source
The human milk oligosaccharide 2'-fucosyllactose alleviates liver steatosis, ER stress, and insulin resistance by reducing hepatic diacylglycerols and improving gut permeability in obese Ldlr-/-Leiden mice [PDF]
, 2022 Non-alcoholic fatty liver disease (NAFLD) is a complex multifactorial disorder that is associated with gut dysbiosis, enhanced gut permeability, adiposity and insulin resistance.
Attema, J. +11 more
core +1 more source
Correction: Precision synbiotic intervention with 2'-fucosyllactose and infant-derived Bifidobacterium modulates gut-immune axis and reduces disease risk in toddlers: a randomized controlled trial [PDF]
Frontiers in NutritionKe Chen +17 more
doaj +2 more sources
Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis [PDF]
, 2019 ビフィズス菌におけるヒトへの適応進化を発見 --母乳オリゴ糖トランスポーターの獲得形質がビフィズスフローラ形成を促す--. 京都大学プレスリリース. 2019-09-05.The human gut microbiota established during infancy has persistent effects on health.
Lo Leggio, Leila +19 more
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, 2023 We explored the potential for the prebiotic oligofructose and prebiotic candidate 2'fucosyllactose, alone and in combination (50:50 blend) to induce physiologically relevant increases in neurotransmitter (γ-aminobutyric acid, serotonin, tryptophan, and ...
Robert Adrian Rastall +5 more
core +1 more source
Determination of 2′-Fucosyllactose and Lacto-N-neotetraose in Infant Formula
Molecules, 2018 Human milk oligosaccharides (HMO) are the third most abundant solid component of human milk. It is likely that they are responsible for at least some of the benefits experienced by breast-fed infants.
Sean Austin +4 more
doaj +1 more source
Microorganisms, 2021 Although breast milk is considered the gold standard of nutrition for infant feeding, some circumstances may make breastfeeding difficult. Several commercial milk preparations include synthetic human milk oligosaccharides (HMOs) in their composition ...
Alicja M. Nogacka +10 more
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