Results 71 to 80 of about 12,036 (214)

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, Volume 183, Issue 9, Page 1747-1778, May 2026.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

Circadian Rhythm of Circulating Levels of the Endocannabinoid 2-Arachidonoylglycerol [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2015
Abstract Context: The endocannabinoid (eCB) system is involved in the regulation of food intake and of peripheral metabolism. Although the cross talk between energy metabolism and the circadian system is well documented, little is known about a potential circadian modulation of human eCB activity.
Hanlon, Erin E.C., Tasali, Esra, Van Cauter, Eve, De Wit, H., Leproult, Rachel, Stuhr, Kara K.L., Doncheck, Elizabeth, Hillard, Cecilia C.J.   +7 more
openaire   +2 more sources

Role of cannabinoids in gastrointestinal mucosal defense and inflammation. [PDF]

, 2016
Modulating the activity of the endocannabinoid system influences various gastrointestinal physiological and pathophysiological processes, and cannabinoid receptors as well as regulatory enzymes responsible for the synthesis or degradation of ...
Gyires Klára, Zádori Zoltán Sándor
core   +2 more sources

Review: “The Disappointment Dilemma: Short‐ and Long‐Term Learning From Negative Outcomes”

European Journal of Neuroscience, Volume 63, Issue 9, May 2026.
The habenula routes negative‐outcome signals to VTA, RMTg, and IPN to shape aversive learning and motivation. The lateral habenula encodes acute negative prediction errors to rapidly adapt behavior to threat, fear, and avoidance. The medial habenula integrates repeated stress, drug, and aversive experiences into long‐term negative mood and expectations.
Ines Ibañez‐Tallon, Susanna Molas, Christophe D. Proulx, Joaquin Piriz, Edgar Soria‐Gómez   +4 more
wiley   +1 more source

Lower circulating endocannabinoid levels in children with autism spectrum disorder

Molecular Autism, 2019
Background The endocannabinoid system (ECS) is a major regulator of synaptic plasticity and neuromodulation. Alterations of the ECS have been demonstrated in several animal models of autism spectrum disorder (ASD). In some of these models, activating the
Adi Aran, Maya Eylon, Moria Harel, Lola Polianski, Alina Nemirovski, Sigal Tepper, Aviad Schnapp, Hanoch Cassuto, Nadia Wattad, Joseph Tam   +9 more
doaj   +1 more source

Cannabinoid signalling in TNF-alpha induced IL-8 release [PDF]

, 2006
Original article can be found at: http://www.sciencedirect.com/science/journal/00142999 Copyright Elsevier B.V.
Baydoun, A. R., Molleman, A., Mormina, M. E., Thakur, S., Whelan, C.J.   +4 more
core   +1 more source

UK Medical Cannabis Registry: A Clinical Outcomes Analysis for Migraine

Brain and Behavior, Volume 16, Issue 4, April 2026.
This case series followed patients receiving medicinal cannabis for migraine headache for up to 2 years. At 24 months, there were significant improvements in measures assessing headache impact, anxiety, sleep quality, and general quality of life. Note that 15.27% of patients reported an adverse event, most of which were mild or moderate in severity ...
Lennon Hooper, Simon Erridge, Evonne Clarke, Katy McLachlan, Ross Coomber, Augustin Iqbal, James J. Rucker, Mark W. Weatherall, Mikael H. Sodergren   +8 more
wiley   +1 more source

Distinct serum endocannabinoid profiles in treatment-naïve Han Chinese children with ADHD: a case–control pilot study

Frontiers in Neurology
ObjectiveAlthough peripheral endocannabinoid system (ECS) signatures have been implicated in ADHD among European and American populations, evidence from Asian pediatric cohorts remains scarce.
Wenjuan Liao, Xiaobin Tan, Jinhai Lin, Yuchen Wu, Qi Guo, Qucheng Huang, Longhe Yang, Yan Peng   +7 more
doaj   +1 more source

The effects of exercise on circulating endocannabinoid levels—a protocol for a systematic review and meta-analysis

Systematic Reviews, 2022
Background Increased circulating endocannabinoids levels are typically associated with aerobic exercise. This phenomenon is associated with a “runner’s high,” a state of euphoria and well-being experienced after a long exercise.
Viviane Bristot, Giorgio Poletto, Débora Maria Russiano Pereira, Melina Hauck, Ione Jayce Ceola Schneider, Aderbal S. Aguiar   +5 more
doaj   +1 more source

Determination of 2-Arachidonoylglycerol by μSPE-LC-MS/MS

, 2016
LC-MS/MS is a powerful analytical technique that provides unequivocal identification and reliable quantification of the analytes, using Selected Reaction Monitoring or Multi Reaction Monitoring acquisition mode.2-Arachidonoylglycerol (2-AG) is the most abundant endocannabinoid, which plays a major role in a wide variety of physiological and ...
BATTISTA, Natalia, SERGI, Manuel
openaire   +4 more sources